Participants
A
Midhat Abdulreda, PhD
Role: Investigator
Email: MAbdulreda@med.miami.edu
Center: University of Miami
Kristin Abraham, PhD
Role: NIDDK Program Staff
Email: abrahamk@niddk.nih.gov
Center: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Domenico Accili, MD
Role: Investigator
Email: da230@columbia.edu
Center: Columbia University
Amanda Ackermann, MD, PhD
Role: Research Staff
Email: ackermanna@email.chop.edu
Center: University of Pennsylvania
Lab: Klaus Kaestner
Joana Almaca, PhD
Role: Investigator
Email: JAlmaca@med.miami.edu
Center: University of Miami
Mark S. Anderson, MD, PhD
Role: Investigator
Email: Mark.Anderson@ucsf.edu
Center: University of California, San Francisco
Charles Ansong, PhD
Role: Investigator
Email: Charles.Ansong@pnnl.gov
Center: Pacific Northwest National Laboratory
Efsun Arda, PhD
Role: Postdoc
Email: ardah@stanford.edu
Center: Stanford University
Job Title: Postdoctoral Fellow
Lab: Seung Kim
Radhika Armandla
Role: Research Staff
Email: aramandla.radhika@vumc.org
Center: Vanderbilt University
Lab: Al Powers
Lucas Armitage
Role: Research Staff
Email: lucasarmitage@ufl.edu
Center: University of Florida
Job Title: Graduate Research Assistant
Lab: Mark Wallet
Role on Project: Studying the role PTPN22 plays in dendritic cells and how it affects its interactions with β cells and cytotoxic CD8+ lymphocytes in type 1 diabetes.
Guillermo Arreaza-Rubin, MD
Role: NIDDK Program Staff
Email: arreaza-rubing@niddk.nih.gov
Center: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Mark Atkinson, PhD
Role: Investigator
Email: atkinson@pathology.ufl.edu
Center: University of Florida
- Defining Islet Heterogeneity Using Single Islet Transcriptomics, Co-Investigator
- HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), Investigator
- HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
- Antibodies for Beta-Cell Subtype Identification by Immunohistochemistry, Investigator
- Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Investigator
Dana Avrahami-Tzfati, PhD
Role: Investigator
Email: danaav@mail.med.upenn.edu
Center: Hadassah-Hebrew University
B
Lauren Becnel, PhD
Role: ESP
Email: lauren.becnel@pfizer.com
Center: Pfizer
Hugh Bender, PhD
Role: Postdoc
Email: rhbender@uci.edu
Center: University of California at Irvine
Job Title: Post-Doctoral Research Fellow
Lab: Chris Hughes
Role on Project: Integrating human pancreatic islets within a vascularized, micro-organ platform.
Nelly Berger
Role: HIREC Staff
Email: nberger@coh.org
Center: City of Hope
Michael Betts, PhD
Role: Investigator
Email: betts@mail.med.upenn.edu
Center: University of Pennsylvania
Sangeeta Bhatia, MD, PhD
Role: Investigator
Email: sbhatia@MIT.EDU
Center: Massachusetts Institute of Technology
Anil Bhushan, PhD
Role: ESP
Email: Anil.Bhushan@ucsf.edu
Center: University of California, San Francisco
Olivier Blondel, PhD
Role: NIDDK Program Staff
Email: blondelol@niddk.nih.gov
Center: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Jeffrey Bluestone, PhD
Role: Investigator
Email: Jeff.Bluestone@ucsf.edu
Center: University of California, San Francisco
Bernd Bodenmiller, PhD
Role: Investigator
Email: bernd.bodenmiller@imls.uzh.ch
Center: University of Zurich
Chiara Borsotti, PhD
Role: Postdoc
Email: cb2943@columbia.edu
Center: Columbia University
Job Title: Postdoctoral Research Scientist
Lab: Megan Sykes
Role on Project: Development of autoimmune insulitis in the personalized immune (PI) humanized mouse model.
Rita Bortell, PhD
Role: Investigator
Email: rita.bortell@umassmed.edu
Center: University of Massachusetts Medical School
Rita Bottino, PhD
Role: Investigator
Email: RBottino@wpahs.org
Center: Allegheny Health Network
Annie Bowles, PhD
Role: Postdoc
Email: acb233@miami.edu
Center: University of Miami
Michael Brehm, PhD
Role: Investigator
Email: michael.brehm@umassmed.edu
Center: University of Massachusetts Medical School
Linford Briant, PhD
Role: Collaborator
Email: linford.briant@ocdem.ox.ac.uk
Center: University of Oxford
Marcela Brissova, PhD
Role: Investigator
Email: marcela.brissova@vanderbilt.edu
Center: Vanderbilt University
- In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas, Investigator
- High-Resolution Analysis of Juvenile Human Pancreas Maturation, Co-Investigator
- HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), co-Invetigator
- HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
- Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Co-Investigator
Todd Brusko, PhD
Role: Investigator
Email: tbrusko@ufl.edu
Center: University of Florida
- Genetic Regulation of Human Beta Cell Destruction, Co-Investigator
- Islet-reactive TCR clones in humanized mice generated with type 1 diabetes patient vs. healthy control hematopoietic stem cells, Investigator
- Characterization of in silico Reconstruction of TCRs for Modeling Autoreactive T cells in T1D, Investigator
- Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator
Peter Buchwald, PhD
Role: Investigator
Email: pbuchwald@med.miami.edu
Center: University of Miami
Kristin Burnum-Johnson, PhD
Role: Investigator
Email: kristin.burnum-johnson@pnnl.gov
Center: Pacific Northwest National Laboratory
C
Alejandro Caicedo, PhD
Role: Investigator
Email: ACaicedo@med.miami.edu
Center: University of Miami
- In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas, Investigator
- High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Co-Investigator
- Real-time Detection of Insulin Surrogate Markers within Physiomimetic Islet Microsystems, Collaborator
Martha Campbell-Thompson, DVM PhD
Role: Investigator
Email: mct@ufl.edu
Center: University of Florida
Sean Campbell, PhD
Role: Research Staff
Email: src2138@cumc.columbia.edu
Center: Columbia University
Job Title: Research Scientist
Lab: Megan Sykes
Role on Project: Dr. Campbell's role on the project is on Specific Aim 2 of the grant. He is working on the optimization of the in vivo functionality of the iPSC-derived beta-like cells. Also, is performing the in vitro studies to compare the immunogenicity of iPSC-derived beta-like cells from healthy controls and type 1 diabetic patients to natural beta cells.
Joan Camunas, PhD
Role: Postdoc
Email: jcamunas@stanford.edu
Center: Stanford University
Joseph Canzano
Role: Research Staff
Email: jcanzano@ufl.edu
Center: University of Florida
Job Title: Bio Scientist
Role on Project: Lab assays and data analysis.
Richard Caprioli, PhD
Role: Investigator
Email: richard.m.caprioli@vanderbilt.edu
Center: Vanderbilt University
Fabian Cardenas
Role: Research Staff
Email: fcar@sas.upenn.edu
Center: University of Pennsylvania
Job Title: Graduate Student
Lab: Paul Gadue
Role on Project: Generation of functional and mature beta cells using hESCs.
Melanie Cash
Role: Research Staff
Email: mcash@pathology.ufl.edu
Center: University of Florida
Job Title: Biological Scientist
Lab: Mark Wallet
Role on Project: Making cell lines to study the regulatory role of PTPN22 by introducing PTPN22 shRNA using lentivirus. In addition, I am assisting with the deleting of PTPN22 via CRIPSR and collection of human blood monocytes by counter-current centrifugal elutriation
Xiaojuan Chen, MD, PhD
Role: Investigator
Email: xc2248@cumc.columbia.edu
Center: Columbia University
Hao Chen, PhD
Role: Investigator
Email: hchen@uthsc.edu
Center: University Tennessee
Josh Chiou
Role: Research Staff
Email: joshchiou@ucsd.edu
Center: University of California, San Diego
Role on Project: Perform integrative analyses of epigenome, transcriptome and diabetes genetic association data
Amit Choudhary, PhD
Role: Investigator
Email: achoud@broadinstitute.org
Center: Broad Institute
Karen Christman, PhD, FAHA
Role: Investigator
Email: christman@eng.ucsd.edu
Center: University of California at San Diego
Jenny Chuang
Role: HIREC Staff
Email: jchuang@coh.org
Center: City of Hope
Remi Creusot, PhD
Role: Investigator
Email: rjc2150@cumc.columbia.edu
Center: Columbia University
D
Chunhua Dai, MD
Role: Investigator
Email: chunhua.dai@vanderbilt.edu
Center: Vanderbilt University
XiaoQing Dai, PhD
Role: Research Staff
Email: xdai@ualberta.ca
Center: University of Alberta
George Daley, MD, PhD
Role: Investigator
Email: George_Daley@hms.harvard.edu
Center: Harvard Medical School
Nichole Danzl, PhD
Role: Investigator
Email: nmd2101@columbia.edu
Center: Columbia University
Job Title: Associate Research Scientist
Lab: Megan Sykes
Role on Project: Dr. Danzl leads the studies for optimization of the PI mouse model and implements these advances into the basic paired T1D versus Healthy Control comparative experiments. She also leads the in vivo functional testing of ES and iPS derivatives to make human islets and a human thymus from the hematopoietic stem cell donor.
Jeffrey Davis
Role: Research Staff
Email: jeffreydavis@fas.harvard.edu
Center: Harvard University
Job Title: Graduate Student
Lab: Doug Melton
Role on Project: Jeff Davis is a graduate student in the Melton lab. Jeff’s work focuses on stressing stem cell-derived beta cells in vitro and in vivo and analyzing changes in gene expression. Jeff then investigates the candidate genes as potential markers of beta cell stress in multiple diabetes-related stress environments.
Sangeeta Dhawan, PhD
Role: Investigator
Email: sdhawan@coh.org
Center: City of Hope
Teresa DiLorenzo, PhD
Role: ESP
Email: teresa.dilorenzo@einstein.yu.edu
Center: Albert Einstein College of Medicine
Juan Dominguez-Bendala, PhD
Role: Investigator
Email: jdominguez2@med.miami.edu
Center: University of Miami
Yuval Dor, PhD
Role: Investigator
Email: yuvald@ekmd.huji.ac.il
Center: Hebrew University of Jerusalem
- Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, Investigator
- Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Co-Investigator
- Non-invasive Diagnosis of Human Beta Cell Damage and Death, Co-Investigator
- The Proteome of Replicating Cells, Investigator
Rafael Drigo, PhD
Role: Postdoc
Email: rdrigo@salk.edu
Center: Salk Institute
E
Thomas Eggerman, MD, PhD
Role: NIDDK Program Staff
Email: eggermant@mail.nih.gov
Center: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Dieter Egli, PhD
Role: Investigator
Email: de2220@columbia.edu
Center: Columbia University
Decio Eizirik, MD, PhD
Role: Investigator
Email: Decio.Laks.Eizirik@ulb.ac.be
Center: University of Brussels
Abdelfattah El Ouaamari, PhD
Role: Investigator
Email: abdelfattah.elouaamari@rutgers.edu
Center: Rutgers University
Elise Engquist
Role: Research Staff
Email: eliseengquist@fas.harvard.edu
Center: Harvard University
Job Title: Research Assistant
Lab: Doug Melton
Role on Project: Elise is a research assistant in the Melton lab. Elise’s main focus is to optimize the protocols used to derive mature SC-Beta cells from human embryonic stem cells with the goal of making it more robust and efficient as well as enhancing the functionality of terminally differentiated cells. Elise also produces and distributes SC-beta cells to other members of the lab and external collaborators to be used in Beta cell characterization studies and in vivo transplantation experiments.
Carmella Evans-Molina, MD, PhD
Role: Investigator
Email: cevansmo@iupui.edu
Center: Indiana University
F
Michael Feldman, MD, PhD
Role: Investigator
Email: feldmanm@mail.med.upenn.edu
Center: University of Pennsylvania
Jorge Ferrer, MD, PhD
Role: Investigator
Email: j.ferrer@imperial.ac.uk
Center: Imperial College of London
Kenichiro Furuyama, MD, PhD
Role: Investigator
Email: kenichiro.furuyama@unige.ch
Center: University of Geneva
G
Paul Gadue, PhD
Role: Investigator
Email: gaduep@email.chop.edu
Center: Children's Hospital of Philadelphia
- Functional Testing of Candidate HSC-derived Islet Cells, Investigator
- Generation of Functional Endocrine Cell Reporter Pluripotent Cell Lines, Investigator
- Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator
- A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator
Roberto Gaetani
Role: Research Staff
Email: rgaetani@eng.ucsd.edu
Center: University of California at San Diego
Job Title: Research Scientist
Lab: Karen Christman
Role on Project: Biomaterial identification for Islet and hESCs 3D culture.
Feorillo Galivo, PhD
Role: Postdoc
Email: galivo@ohsu.edu
Center: Oregon Health and Science University
Job Title: Postdoc
Lab: Markus Grompe
Alannon Gannon, PhD
Role: Postdoc
Email: agannon@seas.harvard.edu
Center: Harvard University
Job Title: Postdoctoral Fellow
Lab: Kit Parker
Role on Project: Co-lead of the Parker lab effort for the “Islet on a chip” project. I'm developing ECM based hydrogels for on chip housing and investigating the micro-mechanical environment of primary islets.
Yuqian Gao
Role: Research Staff
Email: yuqian.gao@pnnl.gov
Center: Pacific Northwest National Laboratory
Job Title: Scientist
Lab: Tom Metz
Role on Project: She is an analytical chemist working on the development of targeted mass spectrometry assays to validate new biomarker candidates that are initially identified in untargeted mass spectrometry-based omics analyses.
Kerim Gattas-Asfura, PhD
Role: Research Staff
Email: Kerim.GattasAsfura@bme.ufl.edu
Center: University of Florida
Lab: Cherie Stabler
Role on Project: Engineering biomimetic scaffolds to support the long-term health of islets or insulin producing tissues.
Kyle Gaulton, PhD
Role: Investigator
Email: kgaulton@ucsd.edu
Center: University of California, San Diego
Steven George, MD, PhD
Role: Investigator
Email: scgeorge@ucdavis.edu
Center: University of California, Davis
Ivan Gerling, PhD
Role: Investigator
Email: igerling@uthsc.edu
Center: University of Tennessee
Ronald Gill, PhD
Role: Investigator
Email: Ronald.gill@ucdenver.edu
Center: University of Colorado at Denver
Benjamin Glaser, MD
Role: Investigator
Email: ben.glaser@mail.huji.ac.il
Center: Hadassah-Hebrew University
Anna Gloyn, D Phil
Role: Investigator
Email: agloyn@stanford.edu
Center: Stanford University
Robin Goland, MD
Role: Investigator
Email: rsg2@columbia.edu
Center: Columbia University
Maria Golson, PhD
Role: Research Staff
Email: mgolson@mail.med.upenn.edu
Center: University of Pennsylvania
Job Title: Reserach Assistant Professor
Lab: Klaus Kaestner
Role on Project: Focus on beta-cell proliferation and function.
David Gonzalez
Role: Research Staff
Email: david_gonzalez@harvard.edu
Center: Harvard University
Job Title: Research Assistant
Lab: Doug Melton
Role on Project: Working on developing and characterizing methods to differentiate embryonic stem cells into various endocrine cell types on the pancreas with the goal of engineering pancreatic islets of defined composition and structure. David is particularly interested in cell-cell and cell-matrix interactions and their contribution to regulated secretion of hormones. Along with Quinn Peterson, David is involved in a number of collaborations with the Karp and Parker lab to design technologies that will shed light on the biological importance of these interactions and hopes that his work will help improve clinical outcomes of patients with diabetes in the future.
Bryan Gonzalez
Role: Research Staff
Email: bg2450@cumc.columbia.edu
Center: Columbia University
Job Title: Graduate Student
Lab: Dieter Egli
Role on Project: Bryan will work on beta cell generation for molecular comparison of iPS derived beta cells and islet derived beta cells of identical genetic origin.
David Gorkin, PhD
Role: Investigator
Email: dgorkin@ucsd.edu
Center: University of California, San Diego
Peter Gottlieb, MD
Role: Investigator
Email: peter.gottlieb@ucdenver.edu
Center: University of Colorado at Denver
Viviana Gradinaru, PhD
Role: Investigator
Email: viviana@caltech.edu
Center: California Institute of Technology
Rafael Gras, PhD
Role: Postdoc
Email: rg2837@columbia.edu
Center: Columbia University
Job Title: Postdoctoral Fellow
Lab: Hans W. Snoeck
Role on Project: To generate thymic epithelial cells from human pluripotent stem cells for modeling of immune responses in type I diabetes in humanized mice.
Carla Greenbaum, MD
Role: Investigator
Email: cjgreen@benaroyaresearch.org
Center: Benaroya Research Institute
Dale Greiner, PhD
Role: Investigator
Email: Dale.greiner@umassmed.edu
Center: University of Massachusetts Medical School
Jeffrey Grethe, PhD
Role: ESP
Email: jgrethe@ncmir.ucsd.edu
Center: University of California at San Diego
Marina Gritsenko
Role: Research Staff
Email: marina.gritsenko@pnnl.gov
Center: Pacific Northwest National Laboratory
Job Title: Scientist
Lab: Tom Metz
Role on Project: She has more than 20 years of experience in developing and applying methods in particular for proteomics analyses, including protein/peptide extraction/purification, fractionation of proteins/peptides using high performance liquid chromatography, and isobaric chemical labeling of peptides.
Markus Grompe, MD
Role: Investigator
Email: grompem@ohsu.edu
Center: Oregon Health & Science University
H
Kirk Hansen, PhD
Role: Collaborator
Email: kirk.hansen@ucdenver.edu
Center: University of Colorado at Denver
David Harlan, MD
Role: Investigator
Email: David.Harlan@umassmemorial.org
Center: University of Massachusetts Medical School
Chuan He, PhD
Role: Investigator
Email: chuanhe@uchicago.edu
Center: University of Chicago
Matthias Hebrok, PhD
Role: Investigator
Email: Mhebrok@diabetes.ucsf.edu
Center: University of California, San Francisco
Kevan Herold, MD
Role: Investigator
Email: Kevan.herold@yale.edu
Center: Yale University
Pedro Herrera, PhD
Role: Investigator
Email: pedro.herrera@unige.ch
Center: University of Geneva
Martin Hetzer, PhD
Role: Investigator
Email: hetzer@salk.edu
Center: Salk Institute
Dirk Homann, MD
Role: Investigator
Email: dirk.homann@mssm.edu
Center: Mount Sinai Hospital
- HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
- Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, co-Investigator
- Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator
Jennifer Hosford
Role: Research Staff
Email: zorra@ufl.edu
Center: University of Florida
Job Title: Clinical Research Coordinator
Lab: Desmond Schatz
Role on Project: University of Florida Diabetes Research Program Coordinator
Chris Hughes, PhD
Role: Investigator
Email: cchughes@uci.edu
Center: University of California at Irvine
I
Matthew Ishahak
Role: Research Staff
Email: m.ishahak@umiami.edu
Center: University of Miami
Job Title: Graduate Student
Lab: Ashutosh Agarwal
Role on Project: Testing and fabrication of microfluidic microsystem to asses the health and viability of islets.
J
Eddie James, PhD
Role: Investigator
Email: ejames@benaroyaresearch.org
Center: Benaroya Research Institute
Robert Jones
Role: Research Staff
Email: jonesbob@stanford.edu
Center: Stanford University
K
Klaus Kaestner, PhD
Role: Investigator
Email: kaestner@mail.med.upenn.edu
Center: University of Pennsylvania
- Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, Investigator
- Epigenetic Rejuvenation of Human Beta-Cells, Investigator
- HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
- HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
- A New Immunodeficient Mouse Model with Stable Hyperglycemia for the Study of Human Beta-cells, Investigator
- Can Genomic Mosaicism explain the Lobular Nature of Type 1 Diabetes?, Investigator
- Mass Spectrometry-based Proteome Maps for Human Islet Cells, Investigator
John Kappler, PhD
Role: Investigator
Email: kapplerj@njc.org
Center: National Jewish Medical & Research Center
Sally Kent, PhD
Role: Investigator
Email: Sally.Kent@umassmed.edu
Center: University of Massachusetts Medical School
Job Title: Assistant Professor
Seung Kim, MD, PhD
Role: Investigator
Email: seungkim@stanford.edu
Center: Stanford University
- CAR T Cell Targeting of Human Islets, Investigator
- HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
- Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator
- Linking Islet Cell Function and Identity from in vitro to in situ, Co-Investigator
- Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Investigator
- Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator
Yuong-Mo Kim
Role: Research Staff
Email: yuongmo.kim@pnnl.gov
Center: Pacific Northwest National Laboratory
Job Title: Scientist
Lab: Tom Metz
Role on Project: He is an analytical chemist and expert in gas chromatography-mass spectrometry-based metabolomics analysis. He is performing metabolomics analyses of pancreatic islets.
Siddharth Kishore
Role: Research Staff
Email: skishore@mail.med.upenn.edu
Center: University of Pennsylvania
Job Title: Graduate Student
Lab: Paul Gadue
Role on Project: Generation of functional and mature beta cells using hESCs.
Stephan Kissler, PhD
Role: Investigator
Email: Stephan.Kissler@joslin.harvard.edu
Center: Joslin Diabetes Institute
Tatsu Kono, PhD
Role: Research Staff
Email: konot@iu.edu
Center: Indiana University School of Medicine
Job Title: Assistant Research Professor
Lab: Raghu Mirmira
Role on Project: His interest is in islet function and calcium regulation. His work in the HIRN project at Indiana centers on the characterization of ER and ER calcium responses of human β cells to cytokine-mediated stress
Rohit Kulkarni, MD, PhD
Role: Investigator
Email: rohit.kulkarni@joslin.harvard.edu
Center: Joslin Diabetes Center
- Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Investigator
- Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes, Invesigator
- Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Investigator
- One-compound, one-islet: A High-throughput Platform for Small-molecule Discovery, Investigator
Taiyi Diana Kuo, PhD
Role: Research Staff
Email: tk2592@cumc.columbia.edu
Center: Columbia University
Job Title: Associate Research Scientist
Lab: Domenico Accili
Role on Project: Identify effectors of β cell dedifferentiation using the “omics” approach.
Irina Kusmartseva, PhD
Role: Investigator
Email: inkusmartseva@ufl.edu
Center: University of Florida
Jennifer Kyle, PhD
Role: Postdoc
Email: jennifer.kyle@pnnl.gov
Center: Pacific Northwest National Laboratory
Job Title: Postdoctoral Fellow
Lab: Tom Metz
Role on Project: She has been refining liquid chromatography-mass spectrometry-based lipidomics analyses, including the development of novel informatics tools for confident lipid identification. She is performing lipidomics analyses of pancreatic islets.
L
Julia Laskin, PhD
Role: Investigator
Email: julia.laskin@pnnl.gov
Center: Pacific Northwest National Laboratory
Karla Leavens, MD, PhD
Role: Research Staff
Email: LEAVENSK@EMAIL.CHOP.EDU
Center: Children's Hospital of Pennsylvania
Job Title: Endocrinology Fellow
Lab: Paul Gadue
Heiko Lickert, PhD
Role: ESP
Email: heiko.lickert@zimbra.helmholtz-muenchen.de
Center: Institute of Diabetes and Regeneration Research
Dong-Jin Lim, PhD
Role: Postdoc
Email: dan_lim@mit.edu
Center: Harvard Medical School
Job Title: Postdoctoral Fellow
Lab: Jeff Karp
Role on Project: Working on identifying suitable microenvironment for islets and stem cell derived islet-like-clusters . He is also interested in developing assays using mass-spectrometry to gain deeper understanding of the secretomic profile of these cells.
Wendell Lim, PhD
Role: Investigator
Email: Wendell.Lim@ucsf.edu
Center: University of California, San Francisco
Amelia Linnemann, PhD
Role: Investigator
Email: aklinnem@iu.edu
Center: Indiana University School of Medicine
Emma Lundberg, PhD
Role: Investigator
Email: emma.lundberg@scilifelab.se
Center: KTH Royal Institute of Technology
M
Patrick MacDonald, PhD
Role: Investigator
Email: pem@ualberta.ca
Center: University of Alberta
Rene Maehr, PhD
Role: Investigator
Email: rene.maehr@umassmed.edu
Center: University of Massachusetts Medical School
Mohsen Khosravi Maharlooei, PhD
Role: Postdoc
Email: mkm2182@cumc.columbia.edu
Center: Columbia University
Job Title: Postdoctoral Fellow
Lab: Megan Sykes
Role on Project: Generation of personalized immune humanized mice with T1D and HC CD34+ HSCs and HLA-matched fetal thymus in NSG mice transgenic for HLA-A2 and HLA-DQ8 and then vaccinate them with different auto-antigens implicated in T1D induction in order to induce autoimmunity and insulitis in this model.
Dustin Maly, PhD
Role: Investigator
Email: maly@chem.washington.edu
Center: University of Washington
Mark Mamula, PhD
Role: Investigator
Email: mark.mamula@yale.edu
Center: Yale University
Jocelyn Fox, PhD
Role: Research Staff
Email: jm33@ualberta.ca
Center: University of Alberta
Lab: Patrick MacDonald
Anna Martinez Casalas, PhD
Role: Postdoc
Email: annamc@kth.se
Center: KTH Royal Institute of Technology
Clayton Mathews, PhD
Role: Investigator
Email: cxm@ufl.edu
Center: University of Florida
- Defining Islet Heterogeneity Using Single Islet Transcriptomics, Co-Investigator
- Genetic Regulation of Human Beta Cell Destruction, Investigator
- Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator
- Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Investigator
- Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator
Ileana Matta
Role: Research Staff
Email: lmatta@ucsd.edu
Center: University of California, San Diego
Job Title: Research Associate
Lab: Maike Sander
Role on Project: Perform cell enrichment experiments from pancreatic tissue.
Jason McDermott, PhD
Role: Investigator
Email: jason.mcdermott@pnnl.gov
Center: Pacific Northwest National Laboratory
Thomas Metz, PhD
Role: Investigator
Email: thomas.metz@pnnl.gov
Center: Pacific Northwest National Laboratory
Everett Meyer, MD, PhD
Role: Investigator
Email: evmeyer@stanford.edu
Center: Stanford University
Aaron Michels, MD
Role: Investigator
Email: aaron.michels@ucdenver.edu
Center: University of Colorado at Denver
Raghavendra Mirmira, MD, PhD
Role: Investigator
Email: rmirmira@iupui.edu
Center: Indiana University
Jason Moore, PhD
Role: Investigator
Email: jhmoore@mail.med.upenn.edu
Center: University of Pennsylvania
Margaret Morris, PhD
Role: Investigator
Email: MorrisMA@evms.edu
Center: Eastern Virginia Medical School
N
Jerry Nadler, MD
Role: Investigator
Email: nadlerjl@evms.edu
Center: Eastern Virginia Medical School
Ali Naji, MD, PhD
Role: Investigator
Email: Ali.Naji@uphs.upenn.edu
Center: University of Pennsylvania
- Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, co-Investigator
- HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
- HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
- Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Co-Investigator
Hiroyuki Nakai, MD, PhD
Role: Investigator
Email: nakaih@ohsu.edu
Center: Oregon Health & Science University
Maki Nakayama, MD, PhD
Role: Investigator
Email: maki.nakayama@ucdenver.edu
Center: University of Colorado at Denver
Ernesto Nakayasu, PhD
Role: Investigator
Email: ernesto.nakayasu@pnnl.gov
Center: Pacific Northwest National Laboratory
Grace Nauman
Role: Research Staff
Email: gn2242@cumc.columbia.edu
Center: Columbia University
Job Title: PhD Student
Lab: Megan Sykes
Role on Project: Improving human antigen presenting cell reconstitution in the Personalized Immune Mouse system.
Kim-Vy Nguyen-Ngoc, PhD
Role: Postdoc
Email: knguyenngoc@ucsd.edu
Center: University of California at San Diego
Job Title: Postdoctoral Fellow
Lab: Maike Sander
Role on Project: Establish 3D organotypic culture model of pancreatic cells derived from hESCs. Identify strategies to vascularize islet organoids in 3D culture.
Dario Nicetto, PhD
Role: Postdoc
Email: dnicetto@mail.med.upenn.edu
Center: University of Pennsylvania
Job Title: Postdoctoral Fellow
Lab: Ken Zaret
Role on Project: Reconstituting human pancreatic beta cells in multicellular 3D organoids.
Julius Nyalwidhe, PhD
Role: Investigator
Email: nyalwijo@evms.edu
Center: Eastern Virginia Medical School
O
Galya Orr, PhD
Role: Investigator
Email: gayla.orr@pnnl.gov
Center: Pacific Northwest National Laboratory
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Feroz Papa, MD, PhD
Role: Investigator
Email: Feroz.Papa@ucsf.edu
Center: University of California, San Francisco
Audrey Parent, PhD
Role: Investigator
Email: Audrey.parent@ucsf.edu
Center: University of California, San Francisco
Job Title: Postdoctoral Fellow
Lab: Mark Anderson, Matthias Hebrok
Role on Project: Generation of thymic epithelial cells from human pluripotent stem cells and development of humanized mouse models to study thymic function in vivo"
Smit Patel
Role: Research Staff
Email: smit31@ufl.edu
Center: University of Floria
Job Title: Graduate Research Assistant
Lab: Cherie Stabler
Heshan Peiris, PhD
Role: Postdoc
Email: hpeiris@stanford.edu
Center: Stanford University
Job Title: Postdoctoral Fellow
Lab: Seung Kim
Ian Penkala
Role: Research Staff
Email: ianpenk@vet.upenn.edu
Center: University of Pennsylvania
Job Title: Graduate Student
Lab: Ben Stanger
Role on Project: Analyze physiology of human islets in suspension or fibrin-hydrogels.
Vladislav Petyuk, PhD
Role: Investigator
Email: vladislav.petyuk@pnnl.gov
Center: Pacific Northwest National Laboratory
Ed Phelps, PhD
Role: Investigator
Email: EPhelps@bme.ufl.edu
Center: University of Florida
Greg Poffenberger
Role: Research Staff
Email: greg.poffenberger@Vanderbilt.Edu
Center: Vanderbilt University
Job Title: Senior Research Specialist
Lab: Al Powers
Vincent Poitout, PhD
Role: ESP
Email: Vincent.poitout@umontreal.ca
Center: Universite de Montreal
Ben Pope, PhD
Role: Postdoc
Email: pope@seas.harvard.edu
Center: Harvard University
Job Title: Postdoctoral Fellow
Lab: Kit Parker
Role on Project: Co-lead of the Parker lab effort for the “Islet on a chip” project. I’m developing on-chip assays of islet function and a platform for in vitro metabolic circuits
Al Powers, MD
Role: Investigator
Email: al.powers@vanderbilt.edu
Center: Vanderbilt University
- High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator
- HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), Investigator
- HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
- Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator
- Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Investigator
- Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator
- Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Co-Investigator
Sebastian Preissl, PhD
Role: Investigator
Email: spreissl@ucsd.edu
Center: University of California, San Diego
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Wei-Jun Qian, PhD
Role: Investigator
Email: weijun.qian@pnnl.gov
Center: Pacific Northwest National Laboratory
Stephen Quake, PhD
Role: Investigator
Email: quake@stanford.edu
Center: Stanford University
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Siddarth Rawal, MD
Role: Research Staff
Email: SRawal@miami.edu
Center: University of Miami
Job Title: Senior Research Associate
Lab: Ashutosh Agarwal
Role on Project: During the initial phase, to design the fluidic chips using CAD and then translate the design to a streamlined fabrication process using CNC machining, laser cutting and 3D printing. Once chips are fabricated and fully functional, will work with the team to establish long term islet cell cultures and develop experimental designs to test the health and viability of the islets as well as assess the metabolic properties of the islets.
Christopher Rhodes, PhD
Role: ESP
Email: rhodesc@medimmune.com
Center: MedImmune
Michael Roper, PhD
Role: Investigator
Email: roper@chem.fsu.edu
Center: Florida State University
Job Title: Investigator
Patrik Rorsman, PhD
Role: Collaborator
Email: patrik.rorsman@hmc.ox.ac.uk
Center: University of Oxford
Derrick Rossi, PhD
Role: Investigator
Email: derrick.rossi@childrens.harvard.edu
Center: Children’s Hospital Corp
Kole Roybal, PhD
Role: Investigator
Email: Kole.Roybal@ucsf.edu
Center: University of California, San Francisco
Marjan Rupnik, PhD
Role: Collaborator
Email: marjan.slakrupnik@meduniwien.ac.at
Center: Medical University of Vienna
Holger Russ, PhD
Role: Investigator
Email: HOLGER.RUSS@UCDENVER.EDU
Center: University of Colorado, Denver
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Maike Sander, MD
Role: Investigator
Email: masander@ucsd.edu
Center: University of California, San Diego
- A 3D Biomimetic Human Islet to Model Beta Cell Function in Health and Disease, Investigator
- Functional Testing of Candidate HSC-derived Islet Cells, Investigator
- Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Investigator
- A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Investigator
Sheryl Sato, PhD
Role: NIDDK Program Staff
Email: satos@extra.niddk.nih.gov
Center: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Alexei Savinov, MD
Role: Investigator
Email: alexei.savinov@sanfordhealth.org
Center: Sanford Research/Univ. of South Dakota
Lisa Scudder, PhD
Role: Postdoc
Email: lscudder@seas.harvard.edu
Center: Harvard University
Job Title: Postdoctoral Fellow
Lab: Kit Parker
Role on Project: Works on the electrophysiological response of stem cell derived-beta cells to glucose and islet ion channel biology.
Howie Seay
Role: Research Staff
Email: hrseay@ufl.edu
Center: University of Florida
Job Title: Biological Scientist II
Lab: Todd Brusko
Role on Project: Using FACS-purification, Howie isolates intra-islet CD4+ and CD8+ T cells to construct single-cell cDNA libraries using the Fluidigm C1 platform. RNA-seq is then performed on these cells to determine phenotype and TcR identity, which is compared to T cell populations found in the pancreatic-draining lymph node, spleen, and PBMC from the same tissue donor to discover cellular overlap and potential peripheral biomarkers of disease.
Paolo Serafini, PhD
Role: Investigator
Email: PSerafini@med.miami.edu
Center: University of Miami
Anath Shalev, MD
Role: Investigator
Email: shalev@uab.edu
Center: University of Alabama at Birmingham
Ruth Shemer, PhD
Role: Investigator
Email: shemer.ru@mail.huji.ac.il
Center: Hebrew University of Jerusalem
Bhupinder Shergill
Role: Research Staff
Email: bdshergill@gmail.com
Center: University of California, Davis
Job Title: Laboratory Manager
Lab: Steven George
Tujin Shi, PhD
Role: Investigator
Email: tujin.shi@pnnl.gov
Center: Pacific Northwest National Laboratory
Kevin Shores
Role: Research Staff
Email: kshores@g.harvard.edu
Center: Harvard University
Job Title: Graduate Research Assistant
Lab: Kit Parker
Role on Project: Modeling and design of the Islet-on-a-Chip platform
Dmitry "Dima" Shvarstman, Ph.D.
Role: Research Staff
Email: Dmitry_shvartsman@harvard.edu
Center: Harvard University
Job Title: Senior Scientist
Lab: Doug Melton
Role on Project: Dmitry Shvartsman is the senior scientist in the Melton lab. Dr. Shvartsman’s main task is to manage to cell production group within the Melton lab and additionally, to manage external and internal collaborations, projects, and financial regulations and compliance.
Ruth Singer
Role: Research Staff
Email: Ruthasinger@gmail.com
Center: Columbia University
Job Title: PhD Candidate
Lab: Lori Sussel
Role on Project: Student Researcher
Zhen Song
Role: Research Staff
Email: sonzh@ohsu.edu
Center: Oregon Health and Science University
Job Title: Research Assistant
Lab: Hiroyuki Nakai
Stephan Speier, PhD
Role: Investigator
Email: stephan.speier@tu-dresden.de
Center: Paul-Langerhans-Institute Dresden
Ben Stanger, MD, PhD
Role: Investigator
Email: bstanger@upenn.edu
Center: University of Pennsylvania
Lawrence Stern, PhD
Role: Investigator
Email: Lawrence.stern@umassmed.edu
Center: University of Massachusetts Medical Center
Doris Stoffers, MD, PhD
Role: Investigator
Email: stoffers@mail.med.upenn.edu
Center: University of Pennsylvania
Andraz Stozer, MD, PhD
Role: Collaborator
Email: andraz.stozer@um.si
Center: University of Maribor
Natasa Strbo, MD
Role: Investigator
Email: nstrbo@umail.miami.edu
Center: University of Miami
Philip Streeter, PhD
Role: Investigator
Email: streetep@ohsu.edu
Center: Oregon Health & Science University
Lina Sui, PhD
Role: Postdoc
Email: ls3178@cumc.columbia.edu
Center: Columbia University
Job Title: Postdoctoral Fellow
Lab: Dieter Egli
Role on Project: Modeling diabetes with human induced pluripotent stem cells. I am working on the differentiation of pancreatic beta cells from human induced pluripotent stem cells derived from Type I diabetes patients in vitro and transplantation of derived beta cells in vivo for functionality study.
Lori Sussel, PhD
Role: Investigator
Email: lgs2@cumc.columbia.edu
Center: University of Colorado, Denver
Megan Sykes, MD
Role: Investigator
Email: ms3976@cumc.columbia.edu
Center: Columbia University
- Islet-reactive TCR clones in humanized mice generated with type 1 diabetes patient vs. healthy control hematopoietic stem cells, Investigator
- Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Investigator
- Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator
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Alejandro Tamayo-Garcia
Role: Research Staff
Email: atamayogarcia@med.miami.edu
Center: University of Miami
Job Title: Research Associate
Lab: Peter Buchwald
Role on Project: Conduct rodent islet isolations, in vitro quantitative islet assessment assays, and in vivo rodent experiments.
Qizhi Tang, PhD
Role: Investigator
Email: Qizhi.Tang@ucsf.edu
Center: University of California, San Francisco
Naohiro Terada, MD, PhD
Role: Investigator
Email: terada@pathology.ufl.edu
Center: University of Florida
Lance Thielen, PhD
Role: Postdoc
Email: lthielen@uab.edu
Center: University of Alabama at Birmingham
Fabrizio Thorel, PhD
Role: Investigator
Email: fabrizio.thorel@unige.ch
Center: University of Geneva
Roland Tisch, PhD
Role: ESP
Email: roland_tisch@med.unc.edu
Center: University of North Carolina, Chapel Hill
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Prashanth Vallabhajosyula, MD
Role: Investigator
Email: prashanth.vallabhajosyula@yale.edu
Center: Yale University
Matthias von Herrath, MD
Role: ESP
Email: matthias@liai.org
Center: La Jolla Institute for Allergy and Immunology
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Peng Wang, PhD
Role: Investigator
Email: peng.wang@mssm.edu
Center: Mount Sinai Hospital
Clive Wasserfall
Role: Investigator
Email: clive@uf.edu
Center: University of Florida
Bobbie-Jo Webb-Robertson, PhD
Role: Investigator
Email: bobbie-jo.webb-robertson@pnnl.gov
Center: Pacific Northwest National Laboratory
Ryan White, PhD
Role: Investigator
Email: ryan.white@uc.edu
Center: University of Cincinnati
Matthew Wortham, PhD
Role: Postdoc
Email: mwortham@ucsd.edu
Center: University of California at San Diego
Job Title: Postdoctoral Fellow
Lab: Maike Sander
Role on Project: Design of conditions to optimize β-cell survival and function in biomimetic devices. Physiological characterization of islets cultured in devices or embedded in extracellular matrix.
Christopher Wright, D Phil
Role: Investigator
Email: chris.wright@vanderbilt.edu
Center: Vanderbilt University
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Guanlan Xu, PhD
Role: Postdoc
Email: guanlanxu@uabmc.edu
Center: University of Alabama at Birmingham
Y
Yong-Guang Yang, MD, PhD
Role: Investigator
Email: yy2324@columbia.edu
Center: Columbia University
Mingder Yang, PhD
Role: Investigator
Email: mdyang@ufl.edu
Center: University of Florida
Job Title: nPOD Coordinator
Lab: Mark Atkinson
Role on Project: nPOD liaison
Kisuk Yang, PhD
Role: Postdoc
Email: kisuky@mit.edu
Center: Massachusetts Institute of Technology
Job Title: Postdoctoral Fellow
Lab: Jeffrey Karp
Role on Project: Recapitulation of in vivo-like pancreatic islet niches for functional islet differentiation of human pluripotent stem cells.
Christine Yoon
Role: Research Staff
Email: cjyoon@bu.edu
Center: Boston University
Job Title: Graduate Student
Lab: Chris Chen
Role on Project: Bioengineering approaches to controlling vascular interactions and perfusion with parenchymal cells.
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Ken Zaret, PhD
Role: Investigator
Email: zaret@mail.med.upenn.edu
Center: University of Pennsylvania
Chun Zeng, PhD
Role: Postdoc
Email: c2zeng@ucsd.edu
Center: University of California, San Diego
Job Title: Assistant Project Scientist
Lab: Maike Sander
Joe Zhou, PhD
Role: Investigator
Email: jqz4001@med.cornell.edu
Center: Weill Cornell Medical College