HIRN

NIH Funding Opportunities

HIRN HPAC: High-Resolution Exploration of the Human Islet Tissue Environment (RFA-DK-21-017). Due March 22, 2021
Characterization of Islet-derived Extracellular Vesicles for Improved Detection, Monitoring, Classification, and Treatment of Type 1 Diabetes (RFA-DK-21-016). Due Nov 3, 2021
Bioinformatics Interdisciplinary Predoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases (PAR-19-378) (PAR-19-379)

NIH NIDDK Workshop: "Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases”

The NIH NIDDK is sponsoring a workshop on “Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases” to be held on March 14-15, 2022 at Natcher Auditorium. The goal of this 1.5-day workshop will be to gather clinical and basic science investigators who are interested in diseases of the exocrine and/or endocrine pancreas and in achieving an understanding of how the two compartments interact in disease. This workshop will provide an opportunity for investigators in exocrine diseases to come together with those studying islets in diabetes as a means to foster interdisciplinary discussion and identify areas for advancement. Learn more HERE.

Registration Deadline: March 1, 2022

HIRN 2021 Trainee Scholarship Recipients

The following are recipients of HIRN 2021 Trainee Scholarships. These trainees submitted submitted abstracts that were competitively reviewed by members of the HIRN Annual Meeting Planning Committee and selected as being highly meritorious. Click HERE to learn more about the recipients.

The Human Islet Research Network (HIRN) was established in 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.

Research Resources

Latest News

November 2021 Webinar: “FAIR Data and You: Are you ready for 2023?”

Learn how to succeed with your next NIH grant: New Data Mandates and Opportunities Tuesday, November 30, 2021 (11:00 AM Pacific | 2:00 PM Eastern) Presentations by: Jeff Grethe, University…

NIH NIDDK Workshop: “Integrated Physiology of the Exocrine & Endocrine Compartments in Pancreatic Diseases” (March 2022)

NIH NIDDK Workshop “Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases Workshop” The NIH NIDDK is hosting a 1.5-day workshop will be to gather clinical and basic…

HIRN 2021 Trainee Scholarship Recipients

The following trainees are recipients of the HIRN 2020 Scholarship based on competitive review of abstracts by members of the HIRN Planning Committee. Giorgio Basile, PhD Institution: Joslin Diabetes Center…

Independent Research Initiatives

Consortium on Beta Cell Death and Survival

CBDS is using human pancreatic tissues to discover mechanisms of cellular stress or dysfunction that may contribute to the development of autoimmunity in at-risk individuals, to identify specific biomarkers of the asymptomatic phase of T1D, and to develop innovative strategies to stop beta cell destruction early in the disease process.

Consortium on Human Islet Biomimetics

CHIB is combining advances in beta cell biology and stem cell biology with tissue engineering technologies to develop microdevices that support functional human islets.

Consortium on Modeling Autoimmune Interactions

The CMAI is developing innovative approaches to model basic aspects of human T1D immunobiology using novel in vivo and in vitro platforms.

Consortium on Targeting and Regeneration

CTAR is investigating methods to increase or maintain functional beta cell mass in T1D through targeted manipulation of islet plasticity or engineered protection of beta cells from immune-mediated destruction.

Human Pancreas Analysis Consortium

The Human Pancreas Analysis Consortium (HPAC) is investigating the physical and functional organization of the human islet tissue environment, the cell-cell relationships within the pancreatic tissue ecosystem, and the contributions of non-endocrine components (acinar, ductal, vascular, perivascular, neuronal, lymphatic, immune) to islet cell function and dysfunction.

HIRN-OPP

Opportunity Pool Projects

The Human Islet Research Network (HIRN) was established In 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.

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