HIRN

HIRN Funding Opportunities

- HIRN HPAC: High-Resolution Exploration of the Human Islet Tissue Environment (RFA-DK-21-017). Due March 3, 2022

- HIRN Catalyst Award (Internal Initiative). Due May 2, 2022.

- NIH Gateway Awards (RFA-DK-21-030). Due June 1, 2022 and March 20, 2023. New Investigators will engage in T1D oriented research networks (HIRN, TrialNet or TEDDY).

IIDP Islet Isolation Centers RFP

The Integrated Islet Distribution Program is seeking experienced human islet isolation centers to apply for their Affiliated Islet Isolation Centers Requests for Proposals.

Applications are due by 3/31/2022.

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NIH NIDDK Workshop: "Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases”

The NIH NIDDK is sponsoring a workshop on “Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases” to be held on March 14-15, 2022 at Natcher Auditorium. The goal of this 1.5-day workshop will be to gather clinical and basic science investigators who are interested in diseases of the exocrine and/or endocrine pancreas and in achieving an understanding of how the two compartments interact in disease.

Registration Deadline: March 1, 2022

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HIRN 2021 Trainee Scholarship Recipients

The following are recipients of HIRN 2021 Trainee Scholarships. These trainees submitted submitted abstracts that were competitively reviewed by members of the HIRN Annual Meeting Planning Committee and selected as being highly meritorious.

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The Human Islet Research Network (HIRN) was established in 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.

Research Resources

Latest News

January 2022 Webinar: “mRNA Modifications in Islet Biology”

January 27, 2022 (2:00 PM Eastern / 11:00 am Pacific) Presented by: Rohit N Kulkarni, MD, PhD, Joslin Diabetes Center Dario F De Jesus, PhD, Joslin Diabetes Center Topics discussed:…

Gateway Investigator RFA

New Investigator Gateway Award for Collaborative T1D Research (RFA DK-21-030) The New Investigator Gateway Award in T1D Research is designed to support a robust pipeline of innovative projects and talented new…

HIRN Catalyst Initaitive (2021)

Internal HIRN Funding Opportunity: A new funding initiative to support investigators developing bold, innovative, and challenging projects that will catalyze the field and provide important advances in topics of interest…

Independent Research Initiatives

Consortium on Beta Cell Death and Survival

CBDS is using human pancreatic tissues to discover mechanisms of cellular stress or dysfunction that may contribute to the development of autoimmunity in at-risk individuals, to identify specific biomarkers of the asymptomatic phase of T1D, and to develop innovative strategies to stop beta cell destruction early in the disease process.

Consortium on Human Islet Biomimetics

CHIB is combining advances in beta cell biology and stem cell biology with tissue engineering technologies to develop microdevices that support functional human islets.

Consortium on Modeling Autoimmune Interactions

The CMAI is developing innovative approaches to model basic aspects of human T1D immunobiology using novel in vivo and in vitro platforms.

Consortium on Targeting and Regeneration

CTAR is investigating methods to increase or maintain functional beta cell mass in T1D through targeted manipulation of islet plasticity or engineered protection of beta cells from immune-mediated destruction.

Human Pancreas Analysis Consortium

The Human Pancreas Analysis Consortium (HPAC) is investigating the physical and functional organization of the human islet tissue environment, the cell-cell relationships within the pancreatic tissue ecosystem, and the contributions of non-endocrine components (acinar, ductal, vascular, perivascular, neuronal, lymphatic, immune) to islet cell function and dysfunction.

HIRN-OPP

Opportunity Pool Projects

The Human Islet Research Network (HIRN) was established In 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.

Find Out More