Job Opportunity: HIRN Scientific Data Curator
The Human Islet Research Network (HIRN) Enhancement Center is hiring a “Scientific Data Curator”.
This individual will work directly with scientists around the world, to advance & promote HIRN, gather & generate required information needed to register, annotate, & publicize scientific resources in systems
HIRN 2021 Trainee Scholarship Recipients
The following are recipients of HIRN 2021 Trainee Scholarships. These trainees submitted submitted abstracts that were competitively reviewed by members of the HIRN Annual Meeting Planning Committee and selected as being highly meritorious. Click HERE to learn more about the recipients.
Diabetes Research Centers Virtual Seminar Series
To address the disruption in seminars & scientific interactions at the onset of the Covid-19 pandemic, nine NIDDK-sponsored Diabetes Research Centers (DRCs) and three Centers for Diabetes Translational Research (CDTRs) established a weekly Virtual Seminar series. Anyone can register for the seminars, which are free and open to the public (registration required).
NIH Funding Opportunities
- Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (RFA-DK-21-006). Due: October 20, 2021
- Characterization of Islet-derived Extracellular Vesicles for Improved Detection, Monitoring, Classification, and Treatment of Type 1 Diabetes (RFA-DK-21-016). Due Nov 3, 2021
- Bioinformatics Interdisciplinary Predoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases (PAR-19-378) (PAR-19-379
HUMAN ISLET RESEARCH NETWORK MISSION
To better understand how human beta cells are lost in Type 1 Diabetes and to find innovative strategies to protect or replace functional beta cell mass in diabetic patients.
The following trainees are recipients of the HIRN 2020 Scholarship based on competitive review of abstracts by members of the HIRN Planning Committee. Giorgio Basile, PhD Institution: Joslin Diabetes Center…Read More
“Introduction to the HIRN Human Pancreas Analysis Program (HPAP): Real World Examples of Successful Data Analyses” Date: Thursday, September 9, 2021 Time: 11:00 AM PDT | 2:00 PM EDT Duration:…Read More
Independent Research Initiatives
CBDS is using human pancreatic tissues to discover mechanisms of cellular stress or dysfunction that may contribute to the development of autoimmunity in at-risk individuals, to identify specific biomarkers of the asymptomatic phase of T1D, and to develop innovative strategies to stop beta cell destruction early in the disease process.
CHIB is combining advances in beta cell biology and stem cell biology with tissue engineering technologies to develop microdevices that support functional human islets.
The CMAI is developing innovative approaches to model basic aspects of human T1D immunobiology using novel in vivo and in vitro platforms.
CTAR is investigating methods to increase or maintain functional beta cell mass in T1D through targeted manipulation of islet plasticity or engineered protection of beta cells from immune-mediated destruction.
The Human Pancreas Analysis Consortium (HPAC) is investigating the physical and functional organization of the human islet tissue environment, the cell-cell relationships within the pancreatic tissue ecosystem, and the contributions of non-endocrine components (acinar, ductal, vascular, perivascular, neuronal, lymphatic, immune) to islet cell function and dysfunction.
Opportunity Pool Projects
The Human Islet Research Network (HIRN) was established In 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.