Comprehensive Proteomics Analysis of Stressed
Human Islets Identifies GDF15 as a Target for
Type 1 Diabetes Intervention

Cell Metabolism. February 4, 2020

Nakayasu et al. used a proteomics-based approach in human islets to study the T1D-related
process of β-cell destruction, identifying a protein, GDF15, that promotes the protection of β cells
and prevents diabetes onset in mice.

New Investigator Pilot Program
in Bioinformatics

This pilot program, through the NIDDK Information Network (dkNET), is designed to encourage new investigators to apply innovative bioinformatics approaches to important research problems in Diabetes, Endocrinology and Metabolic Diseases (DEMD). The dkNET New Investigator Pilot Program is designed to: (i) facilitate the ability of Early Stage and New Investigators with computational and bioinformatics expertise to pursue research questions in DEMD, or (ii) allow Early Stage and New PIs currently pursuing DEMD-related research to explore incorporating computational, statistical, and/or bioinformatics approaches into their research projects.

New HIRN RFA Opportunities

The NIH NIDDK has recently announced HIRN-related funding opportunities

RFA-DK-19-024: HIRN CBDS RFA: "Discovery of Early Type 1 Diabetes Disease Processes in the Human Pancreas"

RFA-DK-19-026: New Investigator Gateway Awards for Collaborative T1D Research

In vivo-mimicking microfluidic perfusion culture of pancreatic islet spheroids

Microenvironmental control of interstitial flow around pancreatic islets effectively maintains islet morphology and function in vitro.

Scientific Advances. November 5, 2019

NIH Information about COVID19

UPDATE: NIH Late Application Policy Due to Public Health Emergency for
United States for 2019 Novel Coronavirus (COVID-19)

NIH Message to Applicants and Recipients of NIH Funds on Flexibilities
Needed for COVID-19

Coronavirus Disease 2019 (COVID-19): Information for NIH Applicants
and Recipients of NIH Funding