HIRN 2022 Annual Investigator Meeting

All members of of the HIRN network are invited to participate in the Annual Investigator Meeting which will be held Wednesday September 14 – Friday September 16, 2022. The meeting will be a hybrid format. We strongly encourage in-person attendance but we will utilize zoom webinar to support remote attendees.

Contact the HIREC for registration details or information on how to participate as an exhibitor.


HIRN Funding Opportunities

    • NIH Gateway Awards (RFA-DK-21-030).

      Due June 1, 2022 and March 20, 2023. New Investigators will engage in T1D oriented research networks (HIRN, TrialNet or TEDDY).

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NIH NIDDK Workshop: "Integrated Physiology of the Exocrine and Endocrine Compartments in Pancreatic Diseases”

**Updated to HYBRID on May 30th**

The NIH NIDDK is sponsoring a workshop for those interested in diseases of the exocrine and/or endocrine pancreas and in achieving an understanding of how the two compartments interact in disease. It will be held June 29-30, 2022 (new dates) in the Natcher Auditorium.

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HIRN 2021 Trainee Scholarship Recipients

The following are recipients of HIRN 2021 Trainee Scholarships. These trainees submitted submitted abstracts that were competitively reviewed by members of the HIRN Annual Meeting Planning Committee and selected as being highly meritorious. 

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To better understand how human beta cells are lost in Type 1 Diabetes and to find innovative strategies to protect or replace functional beta cell mass in diabetic patients.

Our Research

Supporting Collaborative Research since 2014

The Human Islet Research Network (HIRN) was established in 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.

Research Resources

Latest News

HIRN. Meeting Room-2

HIRN 2022 Annual Investigator Meeting: September 14 – 16, 2022

The HIRN 2022 Annual Investigator Meeting will be held Wednesday, September 14 – Friday, September 16, 2022 at the Omni Shoreham Hotel in Washington, DC. Remote participation will be supported…

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2022-04 HIRN_dkNET webinar v2

January 2022 Webinar: “mRNA Modifications in Islet Biology”

Click HERE to access the YouTube video of the recording. January 27, 2022 (2:00 PM Eastern / 11:00 am Pacific) Presented by: Rohit N Kulkarni, MD, PhD, Joslin Diabetes Center Dario F…

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funding 2

Gateway Investigator RFA

New Investigator Gateway Award for Collaborative T1D Research (RFA DK-21-030) The New Investigator Gateway Award in T1D Research is designed to support a robust pipeline of innovative projects and talented new…

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Independent Research Initiatives

Consortium on Beta Cell Death and Survival

CBDS is using human pancreatic tissues to discover mechanisms of cellular stress or dysfunction that may contribute to the development of autoimmunity in at-risk individuals, to identify specific biomarkers of the asymptomatic phase of T1D, and to develop innovative strategies to stop beta cell destruction early in the disease process.

Consortium on Human Islet Biomimetics

CHIB is combining advances in beta cell biology and stem cell biology with tissue engineering technologies to develop microdevices that support functional human islets.

Consortium on Modeling Autoimmune Interactions

The CMAI is developing innovative approaches to model basic aspects of human T1D immunobiology using novel in vivo and in vitro platforms.

Consortium on Targeting and Regeneration

CTAR is investigating methods to increase or maintain functional beta cell mass in T1D through targeted manipulation of islet plasticity or engineered protection of beta cells from immune-mediated destruction.

Human Pancreas Analysis Consortium

The Human Pancreas Analysis Consortium (HPAC) is investigating the physical and functional organization of the human islet tissue environment, the cell-cell relationships within the pancreatic tissue ecosystem, and the contributions of non-endocrine components (acinar, ductal, vascular, perivascular, neuronal, lymphatic, immune) to islet cell function and dysfunction.


Opportunity Pool Projects

The Human Islet Research Network (HIRN) was established In 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives.

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