Clinical Research and Clinical Trials

Type 1 Diabetes TrialNet

is an international network of researchers who are exploring ways to prevent, delay and reverse the progression of type 1 diabetes.


is an international consortium of six centers assembled to participate in the development and implementation of studies to identify infectious agents, dietary factors, and other environmental agents, including psychosocial factors that trigger type 1 diabetes in genetically susceptible people.


is a search portal to find research resources relevant for research and to keep up to date on new tools, services and mandates to support robust and reproducible science. dkNET serves as an information hub for the
research community and is funded by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).

Clinical Islet Transplantation Consortium

is a network of clinical centers and a data coordinating center established to conduct studies of islet transplantation in patients with type 1 diabetes.

Pathology, Islet Resources, and Animal Models

The Network for Pancreatic Organ donors with Diabetes (nPOD)

is a JDRF-supported research program. It is a collaborative research project that supports nPOD approved diabetes investigators by freely providing rare and difficult to obtain tissues from type 1 and type 2 diabetes donors.

Integrated Islet Distribution Program (IIDP)

A NIH National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) funded project that coordinates the distribution of high quality human islets to the diabetes research community, in order to advance scientific discoveries and translational medicine. 

Central NIDDK Repositories

The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) established Central NIDDK Repositories for biosamples and data collected in clinical studies.

The Jackson Laboratory (TJL)

The NIDDK has funded a Type 1 Diabetes Resource (T1DR) at The Jackson Laboratory (TJL). The purpose of this resource is to collect and cryopreserve ~150 mouse stocks important to research in type 1 diabetes.

Funding Agencies


Support for the Human Islet Research Network (HIRN) is provided by the NIDDK and by the Type 1 Diabetes Special Statutory Funding Program

Helmsley Charitable Trust

The HIRN gratefully acknowledges support provided by a grant from The Leona M. and Harry B. Helmsley Charitable Trust for the 2015 – 2019 HIRN Annual Investigator Meetings.



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