Human Islet Research Network


Clinical Research and Clinical Trials


Type 1 Diabetes TrialNet is an international network of researchers who are exploring ways to prevent, delay and reverse the progression of type 1 diabetes.

  TEDDY is an international consortium of six centers assembled to participate in the
development and implementation of studies to identify infectious agents, dietary factors,
and other environmental agents, including psychosocial factors that trigger type 1 diabetes
in genetically susceptible people.
dkNET is a search portal to find research resources relevant for research
and to keep up to date on new tools, services and mandates to support
robust and reproducible science. dkNET is an information hub for the
research community and is funded by the National Institute of Diabetes
and Digestive and Kidney Diseases (NIDDK).
  The Clinical Islet Transplantation Consortium is a network of clinical centers and
a data coordinating center established to conduct studies of islet transplantation
in patients with type 1 diabetes.


Pathology, Islet Resources, and Animal Models


The Network for Pancreatic Organ donors with Diabetes (nPOD) is a JDRF-supported research program. It is a collaborative research project that supports nPOD approved diabetes investigators by freely providing rare and difficult to
obtain tissues from type 1 and type 2 diabetes donors.


The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the
National Institutes of Health (NIH) funded Integrated Islet Distribution Program (IIDP)
coordinates the distribution of high quality human islets to the diabetes research community,
in order to advance scientific discoveries and translational medicine. 





The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) of the National Institutes of Health (NIH) established Central NIDDK Repositories for biosamples and data collected in clinical studies. The purpose of the Central Repositories is to expand the usefulness of these studies by providing access to the biosamples and data to a wider research community beyond the end of the study.

  The NIDDK has funded a Type 1 Diabetes Resource (T1DR) at The Jackson Laboratory (TJL). The purpose of this resource is to collect and cryopreserve ~150 mouse stocks important to research in type 1 diabetes.This major NIDDK-directed collaborative effort currently has an increased emphasis on preclinical research model development. 



Funding Agencies


Support for the Human Islet Research Network (HIRN) is provided by the NIDDK and by the Type 1 Diabetes Special Statutory Funding Program.


The HIRN gratefully acknowledges support provided by a grant from The Leona M. and Harry B. Helmsley Charitable Trust for the 2015 – 2019 HIRN Annual Investigator Meetings.