Characterization of Islet-derived Extracellular Vesicles for Improved Detection, Monitoring, Classification, and Treatment of Type 1 Diabetes (R01 Clinical Trial Not Allowed) (RFA-DK-21-016)

National Institute of Diabetes and Digestive and Kidney Diseases

This initiative will support the development of tools and experimental platforms for the purification and characterization of Extracellular Vesicles (EV) originating from the human pancreatic islet and its broader tissue environment in healthy individuals, and individuals with T1D or at-risk of developing the disease. It will also support the exploration of the contribution of pancreatic EV biology to islet function, dysfunction and T1D disease initiation; the development of EV-based diagnostic tools for disease monitoring and classification; and the use of pancreatic EV biology to identify novel therapeutic targets.

Application Due Date: November 3, 2021
Expiration Date: November 4, 2021

Development of New Technologies and Bioengineering Solutions for the Advancement of Cell Replacement Therapies for Type 1 Diabetes (T1D) (R01 Clinical Trial Optional) (RFA-DK-21-006)

National Institute of Diabetes and Digestive and Kidney Diseases

This Funding Opportunity Announcement (FOA) encourages applications from institutions/organizations proposing original research addressing barriers that limit progress toward effective cell therapies for type 1 diabetes (T1D). The purpose is to support research leading to the development and testing of novel and supportive technologies for the improvement of cell interventions using novel cell sources, immune-modulatory strategies, biomaterials and devices for T1D treatment.

Application Due Date: October 20, 2021
Expiration Date: October 21, 2021

HIRN Emerging Leaders in T1D (2020)

The Human Islet Research Network (HIRN) announces a new funding initiative to provide support and protected time for senior postdoctoral fellows seeking to pursue studies that will enhance their transition toward independent research careers. Applications are sought from experienced postdoctoral fellows with a minimum of two years of ongoing postdoctoral experience who intend to continue research careers in scientific areas supported by the Human Islet Research Network. This opportunity is designed specifically for applicants proposing research that does not involve leading an independent clinical trial, a clinical trial feasibility study, or an ancillary study to a clinical trial that is itself comprised of a clinical trial intervention.

Key Dates:

Posted Date June 15, 2020
Letter of Intent Due Date September 30, 2020
Application Due Date October 30, 2020
Scientific Review November/December 2020
Start Date February 1, 2021
Expiration Date October 31, 2020

Apply here!

For more information please review the attached grant proposal document.

Click here to access the Frequently Asked Questions regarding this funding initiative. This webpage will be updated throughout the submission process.

Please contact the HIRN Enhancement Center with any questions.

Catalytic Tool and Technology Development in Kidney, Urologic, and Hematologic Diseases (R21 Clinical Trial Not Allowed) (PAR-20-140)

National Institute of Diabetes and Digestive and Kidney Diseases

This Funding Opportunity Announcement (FOA) is intended to support tool or technology development projects, opening new areas of science or translational research. The projects supported by this FOA could involve proof-of-concept studies, prototyping, optimization of a technology for the unique anatomy or physiology of these organ systems, and refinement of technical specifications for subsequent deployment of the technology in laboratory or clinical settings.

Application due date: Standard dates apply
Expiration date: May 8, 2023

Bioinformatics Interdisciplinary Predoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases (F31) (PAR-19-378)

National Institute of Diabetes and Digestive and Kidney Diseases

This funding opportunity is to enable promising predoctoral fellows to obtain interdisciplinary training during the dissertation phase of their training from outstanding faculty sponsors in bioinformatics and scientific research relevant to the mission of NIDDK’s Division of Diabetes, Endocrinology and Metabolic Diseases (DDEMD). This training will require mentorship in both bioinformatics and metabolic disease disciplines. In order to advance bioinformatics science and encourage its application to these diseases and disorders, NIDDK invites applications from individuals with novel individual development plans (IDP). The fellowship training plan should focus on interdisciplinary approaches and mentorship among data or computer science and medicine in topics related to diabetes, endocrinology and metabolic diseases.

Application due date: Standard dates apply 
Expiration date: September 8, 2022

Bioinformatics Interdisciplinary Postdoctoral Fellowship in Diabetes, Endocrinology and Metabolic Diseases (F32) (PAR-19-379)

National Institute of Diabetes and Digestive and Kidney Diseases

This Funding Opportunity Announcement (FOA) is to enable promising postdoctoral fellows to obtain interdisciplinary training from outstanding faculty sponsors in bioinformatics and scientific research relevant to the mission of NIDDK’s Division of Diabetes, Endocrinology and Metabolic Diseases (DDEMD). This training will require mentorship in both bioinformatics and metabolic disease disciplines. In order to advance bioinformatics science and encourage its application to these diseases and disorders, NIDDK invites applications from individuals with novel individual development plans (IDP). The fellowship training plan should focus on interdisciplinary approaches and mentorship among data or computer science and medicine in topics related to diabetes, endocrinology and metabolic diseases.

Application due date: Standard dates apply 
Expiration date: September 8, 2022

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