Integrated Program for Human Pancreas Procurement and Analysis

Contact PI: Al Powers, MD, Vanderbilt University (UC4 DK112232)

Mark Atkinson, PhD, Investigator, University of Florida
Marcela Brissova, PhD, co-Investigator, Vanderbilt University
Mingder Yang, PhD, co-Investigator, University of Florida
Irina Kusmartseva, PhD, co-Investigator, University of Florida

Start Date: September 20, 2016
End Date: August 31, 2021


The Integrated Program for Human Pancreas Analysis at Vanderbilt University and the University of Florida (UC4 DK112232) is working collaboratively with the University of Pennsylvania (UC4 DK112217) to increase our understanding key aspects of human type 1 diabetes (T1D) pathogenesis, especially the molecular events in the pancreas and islets. Investigators in the Florida and Vanderbilt groups are using infrastructure and expertise to identify human pancreata from individuals with new-onset T1D or at high-risk for T1D. The groups at the University of Pennsylvania, Vanderbilt, and Florida are collecting and phenotyping the pancreas and islets using new and emerging technologies to generate new knowledge, resources, and datasets that will be made available to HIRN investigators and scientists interested in T1D. In 2021, the research groups integrated into one formal grant (UC4 DK112217) to continue efforts on this project. 

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