HIRN Review Series in Molecular Metabolism (2021-2023)
Through efforts by the Trans-Network Committee (TNC), the HIRN was invited to participate in a review series published by Molecular Metabolism. A link to the virtual digital collection is available HERE and below is a summary of all eight publications from this review series.
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From Type 1 Diabetes Biology to Therapy: The Human Islet Research Network
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What is a β Cell?
Klaus H Kaestner, -
Modeling Human T1D-associated Autoimmune Processes
Mohsen Khosravi-Maharlooei, Rachel Madley, Chiara Borsotti, Leonardo M.R. Ferreira,
Robert C. Sharp, Michael A. Brehm, Dale L. Greiner, Audrey V. Parent, Mark S. Anderson,
Megan Sykes, Remi J. Creusot
February 2022
- Emerging Diabetes Therapies: Bringing Back the Beta-cells
Giorgio Basile, Mizra Muhammad Fahd Qadir, Franck Mauvais-Jarvas, Ricardo Pastori,
Holger Russ, Bridget Wagner, Juan Dominguez-Bendala
March 2022 - Extracellular Vesicles in β Cell Biology: Role of Lipids in Vesicle Biogenesis, Cargo, and Intercellular Signaling
Gebecca S Aguirre, Abhishek Kulkarni, Matthew W. Becker, Xiaoyong Lei, Soumyadepp Sarkar,
Sasanka Ramanadham, Edward A. Phelps, Ernesto S. Nakayasu, Emily K. Sims, Raghu G. Mirmira
September 2022 - Stem Cell-based Multi-tissue Platforms to Model Human Autoimmune Diabetes
Karla Leavens, Juan R. Alvarez-Dominguez, Linda T. Vo, Holger A. Russ, Audrey V. Parent
December 2022 - The Beta Cell-immune Cell Interface in Type 1 Diabetes (T1D)
Eddie James, Alok V Joglekar, Amelia K Linnemann, Holger A Russ, Sally C Kent
September 2023 - Untangling the Genetics of Beta Cell Dysfunction and Death in Type 1 Diabetes
Catherine Robertson, Ruth Elgamal, Belle Henry-Kanarek, Peter Arvan, Shuibing Chen, Sangeeta Dhawan, Decio Eizirik, John Kaddis, Golnaz Vahedi, Stephen Parker, Kyle Gaulton, Scott Soleimanpour
June 2024