HIRN Review Series in Molecular Metabolism (2021-2022)
Through efforts by the Trans-Network Committee (TNC), the HIRN was invited to participate in a year-long review series published by Molecular Metabolism. Below is a summary of all the publications from this review series.
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From type 1 diabetes biology to therapy: The Human Islet Research Network
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What is a β cell?
Klaus H Kaestner, -
Modeling human T1D-associated autoimmune processes
Mohsen Khosravi-Maharlooei, Rachel Madley, Chiara Borsotti, Leonardo M.R. Ferreira,
Robert C. Sharp, Michael A. Brehm, Dale L. Greiner, Audrey V. Parent, Mark S. Anderson,
Megan Sykes, Remi J. Creusot
February 2022
- Emerging diabetes therapies: bringing back the beta-cells
Giorgio Basile, Mizra Muhammad Fahd Qadir, Franck Mauvais-Jarvas, Ricardo Pastori,
Holger Russ, Bridget Wagner, Juan Dominguez-Bendala
March 2022 - Extracellular vesicles in β cell biology: role of lipids in vesicle biogenesis, cargo, and intercellular signaling
Gebecca S Aguirre, Abhishek Kulkarni, Matthew W. Becker, Xiaoyong Lei, Soumyadepp Sarkar, Sasanka Ramanadham, Edward A. Phelps, Ernesto S. Nakayasu, Emily K. Sims. Raghavendra G. Mirmira
September 2022 - Stem cell-based multi-tissue platforms to model human autoimmune diabetes
Karla Leavens, Juan R. Alvarez-Dominguez, Linda T. Vo, Holger A. Russ, Audrey V. Parent
December 2022
Additional papers in development.