Ashu Agarwal, PhD

University of Miami

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Invesetigator

Joana Almaca, PhD

University of Miami

• Changes in Human Islet Microvasculature during Type 1 Diabetes, Investigator
• Integrative Analysis of Multiomic Signatures and Cellular Function in Human Pancreas Across Developmental Timeline at Single-cell Spatial Resolution, Investigator

Juan Alvarez, PhD

University of Pennsylvania

• Measuring Islet-wide Function with Soft Integrated Nanoelectronics, Investigator

Mark S. Anderson, MD, PhD

University of California, San Francisco

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

Justin P. Annes, MD, PhD

University of California, San Francisco

• Developing a Platform Technology for β-Cell-Targeted Drug Delivery, Investigator

Charles Ansong, PhD

Pacific Northwest National Laboratory

• Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D, Investigator

Rafael Arrojo e Drigo, PhD

Vanderbilt University

• Mapping the Association of Beta Cell Longevity and Senescence in T1D, Investigator

Peter Arvan, MD, PhD

• A Stress-Induced Vicious Cycle in the Development of T1D, Investigator

Amish Asthana, PhD

Wake Forest University Health Sciences

• A microwell perfusion plate for manufacturing and testing Islet-like clusters, Investigator

Mark Atkinson, PhD

University of Florida

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Investigator
• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Dana Avrahami-Tzfati, PhD

Hadassah-Hebrew University

• The Role of Senescent Beta Cells in Type 1 Diabetes and Type 2 Diabetes, Investigator

Michael Betts, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, co-Investigator

Romina Bevacqua, PhD

Mount Sinai School of Medicine

• Identification of Novel Regulatory Mechanisms Driving Human Beta-Cell Maturation and Function, Investigator

Jason Bini, PhD

Yale School of Medicine

• Positron emission tomography to characterize beta cell mass in individuals from multiple stages in the progression of type 1 diabetes, Investigator

Rita Bottino, PhD

Allegheny Health Network

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Michael Brehm, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Investigator

Marcela Brissova, PhD

Vanderbilt University

• Integrative Analysis of Multiomic Signatures and Cellular Function in Human Pancreas Across Developmental Timeline at Single-cell Spatial Resolution, Investigator
• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Todd Brusko, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Alejandro Caicedo, PhD

University of Miami

• Integrative Analysis of Multiomic Signatures and Cellular Function in Human Pancreas Across Developmental Timeline at Single-cell Spatial Resolution, Investigator

Martha Campbell-Thompson, DVM PhD

University of Florida

• Survival and Potential of Insulin-deficient Beta Cells in Type 1 Diabetes, Investigator

Shuibing Chen, PhD

Weill Cornell Medical College

• Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression, Investigator

Amit Choudhary, PhD

Broad Institute

• Development of platforms for beta cell-specific delivery and ligand discovery, Inveestigator

Karen Christman, PhD

University of California at San Diego

• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Co-Investigator

Paul Andrew Clemons, PhD

Broad Institute

• Development of platforms for beta cell-specific delivery and ligand discovery, Investigator

Aaron Cox, PhD

University of Texas Health Science Center at Houston

• GABP is a novel regulator of beta cell metabolism and proliferation, Investigator

Remi Creusot, PhD

Columbia University

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Co-Investigator

Chunhua Dai, MD

Vanderbilt University

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Co-Investigator

George Daley, MD, PhD

Harvard Medical School

• Humanized Mouse Avatars for T1D, Investigator

Sangeeta Dhawan, PhD

City of Hope

• Targeting DNA Hydroxymethylation to Promote Human Beta Cell Function, Investigator

Nicolai Doliba, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Research Staff
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Research Staff

Juan Dominguez-Bendala, PhD

University of Miami

• Using ex vivo, in vivo Models and Patient Mutations to Interrogate Pancreatic Exocrine-Endocrine Cross Talk, Investigator

Yuval Dor, PhD

Hebrew University of Jerusalem

• Survival and Potential of Insulin-deficient Beta Cells in Type 1 Diabetes, Investigator

Decio Eizirik, MD, PhD

University of Brussels

• Integrated Stress Response in Human Islets during Early T1D, Investigator

Abdelfattah El Ouaamari, PhD

Rutgers University

• Neuromodulation for Type 1 Diabetes: Harnessing Sensory Innervation to Promote Regeneration and Function of Insulin-Producing Cells, Investigator

Carmella Evans-Molina, MD, PhD

Indiana University

• Integrated Stress Response in Human Islets during Early T1D, Investigator

Robert Babak Faryabi, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Co-Investigator

Michael Feldman, MD, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator

Leonardo Ferreira, PhD

Medical University of South Carolina

• Dissecting Chimeric Antigen Receptor Function in Human Regulatory T Cells, Investigator

Paul Gadue, PhD

Children's Hospital of Philadelphia

• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

Steven George, MD, PhD

University of California, Davis

• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Co-Investigator

Benjamin Glaser, MD

Hadassah-Hebrew University

• The Role of Senescent Beta Cells in Type 1 Diabetes and Type 2 Diabetes, Investigator

Anna Gloyn, D Phil

Stanford University

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Robin Goland, MD

Columbia University

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Co-Investigator

Dale Greiner, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Investigator

Markus Grompe, MD

Oregon Health & Science University

• Gene Therapy for Diabetes, Investigator

Manami Hara, PhD

University of Chicago

• Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

David Harlan, MD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Co-Investigator

Matthias Hebrok, PhD

University of California, San Francisco

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

Dirk Homann, MD

Mount Sinai Hospital

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Jing Hughes, MD, PhD

• Primary Cilia in Human T1D Pancreas, Investigator

Chris Hughes, PhD

University of California at Irvine

• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Investigator

Dan Huh, PhD

University of Pennsylvania

• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

Eddie James, PhD

Benaroya Research Institute

• HLA multimer based characterization of Islet Resident CD4+ T Cells that Target Beta Cell Epitopes and Neo-epitopes, Investigator

Alok Joglekar, PhD

• Identification of the Cognate Epitopes of Autoreactive T Cells in T1D, Investigator

John Kaddis, PhD

City of Hope

• Human Islet Research Enhancement Center (HIREC), Principal Investigator

Klaus Kaestner, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
• The Role of Senescent Beta Cells in Type 1 Diabetes and Type 2 Diabetes, Investigator

Mark Kay, MD, PhD

Stanford University

• Gene Therapy for Diabetes, Investigator

Sally Kent, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Co-Investigator

Seung Kim, MD, PhD

Stanford University

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
• Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator

Hirotake Komatsu, PhD

City of Hope

• Vascular Network-mimetic Oxygen-Transporting Mesh for Islet Graft, Investigator

Vira Kravets, PhD

University of California, San Diego

• Beta-cells 1st Responders and Functional Paracrine Networks in Healthy and Diabetic Human Islets, Investigator

Rohit Kulkarni, MD, PhD

Joslin Diabetes Center

• Development of platforms for beta cell-specific delivery and ligand discovery, Investigator
• Using ex vivo, in vivo Models and Patient Mutations to Interrogate Pancreatic Exocrine-Endocrine Cross Talk, Investigator

Irina Kusmartseva, PhD

University of Florida

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Co-Investigator

Maggie Lam, PhD

University of Colorado, Denver

• Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D, Co-Investigator

Karla Leavens, MD, PhD

Children's Hospital of Pennsylvania

• Investigation of the Role of HNF1A in Increasing Susceptibility to Type 1 Diabetes, Investigator

Xiaoyong Lei, PhD

• Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Wen-Hong Li

UT Southwestern Medical Campus

• Ultra-sensitive Probes for High Resolution Imaging of Hormone Secretion in Islet Cells of Physiological Preparations, Investigator

Amelia Linnemann, PhD

Indiana University School of Medicine

• Real-time in vivo Analysis of Islet Redox Dynamics, Investigator
• Functional and Molecular Characterization of the Human Islet Interferon Alpha Response, Investigator

Chengyang Liu, MD

University of Pennsylvania

• Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression, Co-Investigator

Baoyu Liu, PhD

University of Utah

• On the Plasticity of Beta-cell Antigen Recognition by Diabetogenic CD8 T cells, Investigator

Jing Liu, PhD

Indiana University-Purdue University

• Image based spatial transcriptomics to identify Beta Cell phenotypes in Type 1 Diabetes, Investigator

Patrick MacDonald, PhD

University of Alberta

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Rene Maehr, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Co-Investigator

Dustin Maly, PhD

University of Washington

• Partial Antagonists of IRE1 RNASE - 'pairs' - to treat type 1 diabetes, Investigator

Clayton Mathews, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Michael McManus, PhD

University of California, San Francisco

• iSTAR Tregs, Investigator

Douglas Melton, PhD

Harvard University

• Humanized Mouse Avatars for T1D, Investigator

Thomas Metz, PhD

Pacific Northwest National Laboratory

• Integrated Stress Response in Human Islets during Early T1D, Investigator

Everett Meyer, MD, PhD

Stanford University

• Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator

Jeffrey Millman, PhD

Washington University School of Medicine

• Epigenomic Engineering of Stem Cell-Derived Pancreatic Cells, Investigator

Raghavendra Mirmira, MD, PhD

University of Chicago

• Integrated Stress Response in Human Islets during Early T1D, Investigator

Jason Moore, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator

Ali Naji, MD, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Co-Investigator

Hiroyuki Nakai, MD, PhD

Oregon Health & Science University

• Gene Therapy for Diabetes, Investigator

Ernesto Nakayasu, PhD

Pacific Northwest National Laboratory

• BioStructure & Function Team Leader, Investigator
• Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D, Co-Investigator

Joyce Niland, PhD

City of Hope

• Human Islet Research Enhancement Center (HIREC), Principal Investigator

Scott Oakes, MD

University of Chicago

• Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Galya Orr, PhD

Pacific Northwest National Laboratory

• Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D, Co-Investigator

Feroz Papa, MD, PhD

University of California, San Francisco

• Partial Antagonists of IRE1 RNASE - 'pairs' - to treat type 1 diabetes, Investigator

Audrey Parent, PhD

University of California, San Francisco

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator
• iSTAR Tregs, Investigator

Stephen Parker, PhD

University of Michigan

• Integrative Analysis of Multiomic Signatures and Cellular Function in Human Pancreas Across Developmental Timeline at Single-cell Spatial Resolution, Investigator
• Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression, Investigator

Ed Phelps, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Co-Investigator

Al Powers, MD

Vanderbilt University

• Integrative Analysis of Multiomic Signatures and Cellular Function in Human Pancreas Across Developmental Timeline at Single-cell Spatial Resolution, Investigator
• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Investigator
• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
• Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator

Sasanka Ramanadham, PhD

University of Alabama at Birmingham

• Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Holger Russ, PhD

University of Florida

• Elucidating the Human Beta Cell Translatome in Health and Disease, Investigator

Joao Pedro Saar Werneck de Castro, PhD

University of Miami

• In vivo effects of physical exercise on human islet structure and function, Investigator

Maike Sander, MD

University of California, San Diego

• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Investigator

Leslie Satin, PhD

University of Michigan

• A Stress-Induced Vicious Cycle in the Development of T1D, Investigator

Desmond Schatz, MD

University of Florida

• Survival and Potential of Insulin-deficient Beta Cells in Type 1 Diabetes, Investigator

Anath Shalev, MD

University of Alabama at Birmingham

• Development of an Early Diagnostic Biomarker and Novel Treatment Strategy for T1D, Investigator

Leonard Shultz, PhD

The Jackson Laboratory

• Humanized Mouse Avatars for T1D, Investigator

Scott Soleimanpour, MD

University of Michigan

• A Stress-Induced Vicious Cycle in the Development of T1D, Investigator

Cherie Stabler, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Ben Stanger, MD, PhD

University of Pennsylvania

• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

Doris Stoffers, MD, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator

Lori Sussel, PhD

University of Colorado, Denver

• Lactate-mediated Metabolic Reprogramming of Beta Cells in T1D Contributes to their Enhanced Plasticity and Dedifferentiation, Investigator
• Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D, Investigator

Megan Sykes, MD

Columbia University

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

Qizhi Tang, PhD

University of California, San Francisco

• Tregs as Vehicles for Targeted Delivery of Therapeutic Payload to Human Islets, Investigator
• iSTAR Tregs, Investigator

Naohiro Terada, MD, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Co-Investigator

Luc Teyton, MD, PhD

• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Investigator

Golnaz Vahedi, PhD

University of Pennsylvania

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Co-Investigator
• Dissecting Transcriptomics and Epigenomic Signatures of Immune Cells in T1D, Investigator

Clive Wasserfall

University of Florida

• Survival and Potential of Insulin-deficient Beta Cells in Type 1 Diabetes, Investigator

Bobbie-Jo Webb-Robertson, PhD

Pacific Northwest National Laboratory

• Integrated Stress Response in Human Islets during Early T1D, Investigator

Matthew Wortham, PhD

University of California at San Diego

• Metabolic requirements of pancreatic beta cell proliferation, Investigator

Wenting Wu, PhD

Indiana University

• Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Mingder Yang, PhD

University of Florida

• HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes, Co-Investigator

Han Zhu, PhD

University of California, San Diego

• Gene regulatory programs driving metabolic maturation of human pluripotent stem cell derived β-cells, Investigator