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Active Projects
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HPAP T1D: Human Pancreas Analysis Program for Type 1 Diabetes
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HPAP T2D: Human Pancreas Analysis Program
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Integrative Analysis of Multiomic Signatures and Cellular Function in Human Pancreas Across Developmental Timeline at Single-cell Spatial Resolution
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Linking Human Islet Structural Heterogeneity to Beta Cell State
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Positron emission tomography to characterize beta cell mass in individuals from multiple stages in the progression of type 1 diabetes
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Survival and Potential of Insulin-deficient Beta Cells in Type 1 Diabetes
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The Role of Senescent Beta Cells in Type 1 Diabetes and Type 2 Diabetes
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Using ex vivo, in vivo Models and Patient Mutations to Interrogate Pancreatic Exocrine-Endocrine Cross Talk
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Closed Projects
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Beta-cells 1st Responders and Functional Paracrine Networks in Healthy and Diabetic Human Islets
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Changes in Human Islet Microvasculature during Type 1 Diabetes
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Cooperativity between Calcium and cAMP-inducing Agents in Human Alpha and Beta Cells
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High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential
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HPAP T2D: Human Pancreas Analysis Program (Vanderbilt)
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In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas
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In vivo Effects of Physical Exercise on Human Islet Structure and Function
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Integrated Program for Human Pancreas Procurement and Analysis
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Linking Islet Cell Function and Identity from in vitro to in situ
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Primary Cilia in Human T1D Pancreas
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Single Cell Analysis of the Human Pancreas in Type 1 Diabetes
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Ultra-sensitive Probes for High Resolution Imaging of Hormone Secretion in Islet Cells of Physiological Preparations
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