Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression.

Consortia: HPAC

Fasolino M, Goldman N, Wang W, Cattau B, Zhou Y, Petrovic J, Link VM, Cote A, Chandra A, Silverman M, Joyce EF, Little SC; HPAP Consortium, Kaestner KH, Naji A, Raj A, Henao-Mejia J, Faryabi RB, Vahedi G.  
Immunity. 2020 Feb 6. pii: S1074-7613(20)30030-3. doi:10.1016/j.immuni.2020.01.003. PubMed PMID: 32049053.

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restimulation Inside the β Cell: Molecular Stress Response Pathways in Diabetes Pathogenesis Geometric engineering of organoid culture for enhanced organogenesis in a dish Weight Cycling Impairs Pancreatic Insulin Secretion but Does Not Perturb Whole-Body Insulin Action in Mice With Diet-Induced Obesity Exploring Computational Data Amplification and Imputation for the Discovery of Type 1 Diabetes (T1D) Biomarkers from Limited Human Datasets The type 1 diabetes gene TYK2 regulates β-cell development and its responses to interferon-α Pro-Inflammatory Cytokines Promote the Transcription of Circular RNAs in Human Pancreatic β Cells Mouse models and human islet transplantation sites for intravital imaging Direct Reprogramming of Different Cell Lineages into Pancreatic β-Like Cells Yo-Yo Dieting: Mixed Messages for β-Cell Plasticity Stem cell-based multi-tissue platforms to model human autoimmune diabetes Aging compromises human islet beta cell function and identity by decreasing transcription factor activity and inducing ER stress
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