Diabetes Research Institute, University of Miami

A postdoctoral associate position is available at the Diabetes Research Institute of the University of Miami. The main lines of research in the Beta Cell Regeneration Lab revolve around the development of regenerative strategies for type 1 diabetes, including stem cell differentiation into insulin-producing β-cells and islet regeneration. In particular, our current research is focused on the induction of human pancreatic ductal BMP-responsive progenitor cells, which we have identified and characterized by lineage tracing (Klein et al., Diabetes, 2015; Qadir et al.Cell Reports, 2018); single-cell RNAseq and transplantation of sorted populations (Qadir et al., PNAS, 2020); and organotypic culture (human pancreatic slices) techniques (Qadir et al.Nature Comms, 2020). Our seminal contribution to the development of the latter has enabled for the first time the real-time monitoring of β-cell regeneration in an in vitro setting that resembles the native organ. Applicants for the position should provide a brief statement of research interests, CV, and the names of three references to Dr. Juan Dominguez-Bendala.

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Washington University in St. Louis

A staff scientist is sought to fill a position to work in the diabetes research and regenerative medicine laboratory of Dr. Jeffrey Millman at Washington University in St. Louis. The laboratory focuses on the generation insulin-producing pancreatic β cells for the study and treatment of diabetes. We have a wide diversity of projects involving stem cells differentiation, genetic engineering with CRISPR, disease modeling, transplantation into animal models of diabetes, biomedical engineering, bioinformatics, and single-cell sequencing technologies and has been very productive with publications in high impact journals. The ideal candidate would be able to provide high level support across multiple projects.  Interested applicants are encouraged to send a letter/statement of interests, CV, and contact information for 2-3 references to Dr. Millman.

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The University of Chicago’s Department of Medicine

The University of Chicago’s Department of Medicine is searching for full-time physician scientist faculty members at any rank. Appointees will maintain a productive research program and provide patient care directly. Other responsibilities will include teaching and supervision of trainees and students. We are interested in applicants in any area of scientific investigation and clinical subspecialty, and especially welcome those whose research focus more broadly is in the areas of immunology/inflammation, diabetes, obesity, metabolism, sleep disorders, or cancer biology. Prior to the start of employment, qualified applicants must: 1) have a medical doctorate or equivalent, and 2) hold or be eligible for medical licensure in the State of Illinois. Please send your CV, cover letter, and contact information with 3 references to Dr. Mirmira.

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Joslin Diabetes Center, Harvard Medical School

The Joslin Diabetes Center, Harvard Medical School  has two Post-Doctoral Fellowship open positions in the Kulkarni Lab. Two positions are available immediately for a period of 3 years each. For both positions applications are invited from individuals with a PhD or MD or MD PhD degrees. 1) The first position is for training in exciting projects focused on Metabolism such as defining pathways and identifying mechanisms that regulate pancreatic (endocrine and exocrine) biology including inter-organ cross-talk in the overall maintenance of glucose homeostasis. The projects will utilize including induced pluripotent stem cells, genetically engineered and humanized mouse models. Topics are flexible – some examples include growth factor (e.g. insulin/IGF-1) signaling, mRNA modifications and stem cell biology. Candidates should have a strong background in molecular biology, cell biology (stem/iPS cells) and biochemistry. It is an advantage if candidates have the ability to interrogate “omics” and sequencing datasets. Candidates should possess skills or be willing to learn handling human islets, in vivo animal studies, rodent islet isolation and immunostaining. 2) For the second position candidates with expertise in Bioinformatics will be especially relevant. Prospective candidates should have expertise in handling large ‘omics’ databases and be willing to work closely with other Fellows in the lab to assist in analyses of biological data from diverse projects. Candidates will also be encouraged to develop their own research interests. Applicants for both positions should provide a brief statement of research interests, CV, and the names of three references to  Dr. Kulkarni

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University of Miami, Miller School of Medicine

The Department of Medicine at the University of Miami, Miller School of Medicine, has an exciting opportunity for a full time Postdoctoral Associate. This Postdoctoral Associate position will support Dr. Joao Pedro Werneck with his investigations that focus on implementing in vivo tools to understand the thyroid gland physiology and how exercise impacts human pancreatic islets.  Interested applicants are encouraged to send a letter/statement of interests, CV, and contact information for 2-3 references to Dr. Joao Saar Werneck de Castro.

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The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope

The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope has a postdoctoral position available in the laboratory of Dr. Komatsu / Dr. Kandeel in the Department of Translational Research & Cellular Therapeutics. They are seeking a creative, experienced and highly collaborative postdoctoral associate with a strong interest in the translational research in Type 1 diabetes. The research goal for this position is to establish the extrahepatic islet transplantation strategy in animal models that can be translated into the clinical. Several projects are ongoing with highly productive collaborators including extramural engineers. By integrating our broad knowledge of islet physiology with engineering approaches, we seek to develop novel strategy of islet transplantation. These projects are led by the principal investigator with extensive clinical experience as translational researches. The selected candidate will take initiative in developing the new islet transplantation approaches using animal islet transplantation models. Candidates with clinical experience, beta cell biology and/or molecular biology, are particularly welcome to apply. Interested applicants are encouraged to send a letter/statement of interests, CV, and contact information for 2-3 references to Dr. Hirotake Komatsu.

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Benaroya Research Institute

Benaroya Research Institute’s Center for Interventional Immunology seeking outstanding clinical investigator for faculty position as well as post-doctorate candidates or research fellows interested in clinical/translational research in type 1 diabetes and/or autoimmunity.  Please send your CV, cover letter, and contact information with 3 references to Dr. Carla Greenbaum.

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University of Alberta, Canada

The MacDonald Lab at the University of Alberta in Edmonton, Canada is looking to fill two postdoctoral positions within one or more of the following areas: cell physiology, single-cell biology, cell imaging, electrophysiology, and computational biology. The positions will be held within the Department of Pharmacology and the Alberta Diabetes Institute (ADI), Canada’s largest stand-alone diabetes research centre.  Successful candidates will have access to extensive resources for research through the MacDonald Lab, the ADI, and the University of Alberta Faculty of Medicine and Dentistry. This includes core facilities for molecular biology and biochemistry, sequencing and single-cell work, live-cell imaging, animal services, and more. Please send your CV, cover letter, and contact information with 3 references to Dr. Patrick McDonald.

 

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The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope

The Beckman Research Institute at City of Hope has an opportunity for a Research Associate II, under the direction of Dr. Kaddis. The candidate in this position will work directly with diabetes scientists around the world, to advance and promote the Human Islet Research Network (HIRN). Using related databases and content curation strategies, this individual will gather and generate required information needed to register, annotate, and publicize scientific resources in project registry systems. The applicant will be part of a multi-disciplinary team responsible for developing, managing, checking, and sharing the metadata needed to describe a scientific resource, such as biomedical datasets, biological reagents, documents (e.g. protocols), and/or technologies (e.g. assays).  The candidate will develop content using literature curation methodologies, biological ontologies, controlled vocabularies, and databases, but often requires direct interaction with and feedback from submitting laboratories, i.e. scientists. Metadata completeness and correctness is of primary importance; the applicant will organize and oversee existing registry data, as well as perform reviews of new or modified metadata submissions.  Please send your CV, cover letter, and contact information with 3 references to  Dr. John Kaddis.

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Washington University School of Medicine

The laboratory of Dr. Jeffrey Millman in the Division of Endocrinology, Metabolism, and Lipid Research at Washington University School of Medicine is searching for a postdoctoral associates to lead several new research projects in the lab. The objective of the Millman Lab is to generate and study stem cell-derived beta cells for use in diabetic disease modeling and cell therapy. The candidate must have a PhD in cell biology, biomedical engineering, or related fields and has demonstrated quality publication of their work. The candidate should have experience in stem cell culture and familiarity with techniques common in cell biology labs, including qRT-PCR, flow cytometry, and immunocytochemistry.  Qualified candidates are encouraged to contact Dr. Jeffrey Millman with their CV and the names of three references.

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University of British Columbia

A new Stem Cell and Genome Editing Core Facility situated within the Kieffer Research Group University of British Columbia has an opportunity for a highly motivated and collaborative technician to support diverse regenerative medicine research initiatives. The candidate will assist with the dayto-day operation of the Core, will generate human induced pluripotent cells (iPSCs), and will culture and differentiate human embryonic stem cells (ESCs) and iPSCs down pancreatic lineages.  Candidates should submit a cover letter outlining research interests and fit with the laboratory’s research along with resume.

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Department of Molecular & Medical Genetics at Oregon Health & Science University (OHSU)

The Department of Molecular & Medical Genetics at Oregon Health & Science University (OHSU) in Portland, Oregon, is seeking a highly motivated and enthusiastic post-doctoral fellow to study adeno-associated virus (AAV) and its application for human gene therapy in the lab led by Professor Hiroyuki Nakai, M.D., Ph.D. Specifically, the lab is looking for a post-doctoral researcher who can lead productively several projects including a multi-PI (MPI) NIH project ” U01DK123608 (MPIs: Nakai, Grompe and Kay): Gene Therapy for Diabetes, ” where we seek to develop clinically relevant novel AAV vectors and methods for in vivo regeneration of insulin-secreting beta cells in rhesus macaques and profoundly understand the mechanisms behind the technologies. The main research focuses of the Nakai lab are: (1) AAV vector biology – capsid assembly, genome packaging, and virus-host interactions in rodents and non-human primates; (2) AAV antigen-antibody interactions; (3) developing novel vectors by engineering of AAV capsids; and (4) preclinical studies of gene therapy for the treatment of various human diseases including type I diabetes. Please send a cover letter and C.V. to Dr. Hiroyuki Nakai.

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The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope

The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope is looking for a talented postdoctoral fellow. The collaborative laboratories of Drs. John Kaddis and Bart Roep are jointly seeking innovative postdoctoral candidates to conduct in-silico translational research in the field of type 1 diabetes (T1D). This individual will participate in one or more projects that examine the role of molecular, cellular, genetic, and epidemiological variation in T1D. This candidate will have an opportunity to work with specialists in the fields of immunology, diabetes, and data/computer science. Expertize in statistical methods for disease risk prediction and modeling, as well as clinical data, genome sequence, SNP array, “-omics”, and large-scale genetic association analysis is helpful. Experience with public databases/repositories is highly desired. Necessary skills include those from bioinformatics, computer/data science, mathematics, software engineering, and computational biology.  Interested applicants should send a letter, CV, and contact information for 2-4 references to Dr. John Kaddis.

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Program Director for Integrative Physiology

The National Institute of Diabetes and Digestive and Kidney Diseases is hiring a Program Director for Integrative Physiology of Human Diabetes. A scientist with strong managerial, communications and interpersonal skills, and experience in integrative physiology relevant to diabetes, is sought for the position of Program Director for Integrative Physiology in the Division of Diabetes, Endocrinology, and Metabolic Diseases (DDEMD) in the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), at the National Institutes of Health. Research to be managed by the Director of DDEMD’s Integrative Physiology program is supported through multiple mechanisms, including regular research grants and cooperative agreements. Activities to be pursued include planning, establishing, and overseeing a wide range of goal-directed initiatives to expedite and enhance translational, pre-clinical and clinical research in diabetes. 

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Program Officials

The National Institute of Diabetes and Digestive and Kidney Diseases is hiring program officials with expertise in translational research in any of the following four topic areas as they specifically relate to key questions in diabetes, endocrine or metabolic diseases:

    • Integrative physiology of human diabetes, including physiology of counter-regulatory responses to hypoglycemia, mechanisms involved in regulation of peripheral metabolism, autonomic nervous system regulation of glucose and lipid metabolism, and basic and clinical studies investigating effects of bariatric surgery on diabetes and diabetes-related outcomes;
    • Neuroscience of human behavior and behavior change, including brain and peripheral systems that impact the onset, severity or resolution of diabetes or obesity pathophysiology;  
    • Immune regulation and inflammation, including innate and adaptive immune mechanisms influencing peripheral insulin resistance in animal models and humans;
  • Precision medicine in diabetes and obesity.

The mission of the Division of Diabetes, Endocrinology and Metabolic Diseases is to support broad-based research programs focused on both basic and clinical research in the areas of type 1 and type 2 diabetes and other metabolic diseases.

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Columbia Center for Translational Immunology

The Columbia Center for Translational Immunology (CCTI) has a postdoctoral position available in the group of Dr. Remi Creusot to participate in research investigating the pathophysiology and therapy of autoimmune diabetes. The research will focus primarily on two NIH-funded projects: one studying the development and function of autoreactive T cells in humanized mouse models and a collaborative project on engineered stromal cells to reestablish immune tolerance .  The candidate should have a recent PhD in Immunology, Molecular Medicine or related field with a proven track record of productivity (first authorship in peer-review) journal in English is preferred). In addition, the successful candidate will demonstrate creativity, strong work ethics, motivation and ability to handle multiple projects and to work in a collaborative yet competitive environment, as well as excellent written and verbal communication skills.  Experience with flow cytometry and in vitro immunoassays, animal procedures (including surgery), isolation and culture of immune cells and cell engineering (transduction) is highly desirable. Applicants should send a full CV, a one-page cover letter highlighting research interests and goals, and the name and contact details of 3 references directly to Dr. Remi Creusot.

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The University of California, San Francisco

The University of California, San Francisco, is looking for recent Ph.D to pursue a career in science and biotechnology at the intersection of immunology and aging. People trained in my lab pursue careers in academia, biotech start-ups, venture funds or consultants for large firms. The long-term goal of my research is to understand the role of tissue secretory senescent cells in diseases such as autoimmunity, diabetes and diseases of aging. We have identified key immune cells that can selectively eliminated senescent cells in a number of diseases associated with agingWe use a combination of mouse models of autoimmunity and humanized mouse models transplanted with senescent cells to investigate the underlying mechanism by which tissue senescent cells contribute to the development of the various diseases. We pay salaries that are more generous than traditional academic scales. The collegiality and interdepartmental organization at UCSF fosters interdisciplinary research that helps hone research skills, critical thinking, and scientific writing for a broad range of jobs.  Please send cover letter and CV/resume to Dr. Anil Bhushan.

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Montreal Diabetes Research Center

The Montreal Diabetes Research Center at the University of Montreal, has two Postdoctoral positions available at the Rutter laboratory. The laboratory studies pancreatic beta cell biology and its perturbations in type 2 diabetes (Rutter et al Diabetologia, 63(10):1990-1998. doi: 10.1007/s00125-020-05205-5, 2020). The objectives of the two projects are to explore the role and regulation of interactions between beta cells within the pancreatic islet using live cell imaging and optogenetics (Project 1), and to understand how genomic variants associated with type 2 diabetes impact pancreatic beta cell function (Project 2). The successful applicants will hold a PhD or equivalent. Experience in islet biology and/or glucose homeostasis, calcium signaling and image analysis (Project 1) or CRISPR/Cas9 genome editing, culture of human-derived beta cells or directed differentiation of embryonic stem cells towards a beta cell fate would be advantageous. Candidates with experience in data analysis using R, MATLAB etc. are particularly welcome to apply. Please send a cover letter and curriculum vitae, including three references,
to Dr. Guy Rutter.

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The University of Florida

The University of Florida under the Stabler laboratory is seeking a creative and dedicated postdoctoral associate to join our team in working on translational research in Type 1 diabetes. The research goals for this position are in the translation of our bioactive scaffolds and coatings into preclinical models for validation and optimization. As a highly collaborative laboratory, the Associate will integrate as a part of our team, working together with members of the laboratory, as well as our extensive researcher network. The Associate will be expected to take a leadership role in the laboratory, directing research goals and timelines, mentoring students, and writing reports and publications. Interested candidates should submit a CV, a summary of future research interests and goals, and three references to Dr. Cheri Stabler

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The NIDDK Information Network (dkNet)

The NIDDK Information Network (dkNet) has an open position for a Community Liaison to provide community outreach and lead engagement with the scientific community. This position will support a range of activities linked to community-dkNET partnerships, researcher engagement and knowledge networking. The position will entail engaging with research scientists, students and trainees, government, industry and broader audiences through workshops, in-person outreach events, multimedia, social media and Web-based systems. dkNET was launched by the FAIR Data Informatics Laboratory at the University of California, San Diego to serve the needs of basic and clinical investigators in diabetes, digestive and kidney disease by addressing the challenge of connecting researchers to research resources, assisting researchers with rigor and reproducibility guidelines, supporting researchers in navigating new data sharing requirements, and providing tools in enabling data discovery and hypothesis generation. More information HERE.

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University of Pennsylvania School of Medicine

The Voight lab invites applications for a computational Post-Doctoral position at the University of Pennsylvania School of Medicine, within the Department of Systems Pharmacology and Translational Therapeutics and the Department of Genetics. The lab focuses on translating discoveries from human genetics data into insights about the biological basis and genetic architecture of human disease (ultimately toward developing new therapeutics targets for human disease), and understanding selection during recent human evolution.  Adding some focal work on computational analyses for T2D. The candidate will have a MD, PhD, or equivalent doctorate, with a strong background in one or more of the following areas: statistics, biostatistics, population genetics, human genetics, genetic epidemiology, computational biology and/or genomics, bioinformatics.  To apply, please send (i) a cover letter that includes the names and contacts for three references and a short statement of research interests, and (ii) a current CV to: Dr. Benjamin Voight.

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Vanderbilt Diabetes Center

The Powers & Brissova research group in the Vanderbilt Diabetes Center is a seeking postdoctoral fellows to study human pancreas and islet biology with a focus on gene expression and developmental biology of single cells. We are especially interested individuals with computational or informatics expertise, multimodal, multiplex experience, or live cell imaging experience. Please send current CV to Dr. Al Powers.

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Rutgers, the State University of New Jersey

Rutgers, the State University of New Jersey, is seeking a Research Associate for the Child Health Institute of New Jersey. The position is available in El Ouaamari’s laboratory to investigate the role of the peripheral neurons in the regulation of systemic energy homeostasis in the context of obesity and diabetes. Self-driven, creative, resourceful and independent candidates with a PhD in neuroscience or neurobiology are encouraged to apply. Prior postdoctoral experience in neuroscience or related fields is required. Successful applicants will develop a research program focused on understanding how peripheral neurons control glucose and lipid homeostasis—with the long-term goal of identifying high-value biological data that can be harnessed to design neuromodulation-based strategies to counter obesity and diabetes. The candidate must be skilled in using in vitro and in vivo techniques for manipulating and monitoring neuronal activity and should have strong records of productivity and achievement. Preference will be given to applicants who have experience in diabetes research as well. Please send cover letter and CV to Dr. Abdelfattah El Ouaamari.

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University of Chicago

The University of Chicago beta cell/diabetes research group under the direction of Dr. Raghu Mirmira has funded openings for several postdoctoral research scientists with interest in applying/learning cell biological techniques (immunoprecipitation, immunohistochemistry, confocal imaging), mouse genetic skills, human islet biology, and immunology and inflammation research.  NIH-funded research projects in the Mirmira laboratory include the study of beta cell development and function, human islet gene regulation and mRNA translation, and islet cytokine signaling in the context of type 1 diabetes.  The University of Chicago Diabetes Center is a highly interactive and diverse research environment with a strong history of mentoring and career development of junior scientists.  In addition to a rich research environment, the Center and School of Medicine provide numerous scientific seminar series, career development workshops, and the opportunity to interact with a diverse pool of international scientists in a dynamic and exciting city.  Interested applicants are encouraged to send an updated CV and names of 3 references to Dr. Raghu Mirmira, MD, PhD, Director, Department of Medicine, University of Chicago.

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Diabetes Center of Excellence at the University of Massachusetts Medical School

The Diabetes Center of Excellence at the University of Massachusetts Medical School invites applications for a SENIOR TENURED or JUNIOR TENURE-TRACK basic science or clinical investigator faculty position. The Diabetes Center of Excellence currently consists of basic and physician scientists representing a broad range of disciplines in the biomedical and clinical sciences, with members from several Medical School Departments and Programs working together as central New England’s leading center for diabetes clinical care, innovation, and discovery. The Center occupies state-of-the-art research space on an expanding Medical School campus. Basic investigators benefit from core facilities for deep sequencing, proteomics, genotyping, fluorescence-activated cell sorting, digital imaging/confocal microscopy, genomics/bioinformatics, transgenic/knockout mice, and mouse metabolic phenotyping. Clinical and community investigators benefit from infrastructure for recruitment and retention of research participants, measurement, behavioral and nutritional intervention resources and facilities, and academic-community research partnerships. Adult and pediatric clinical efforts of the Diabetes Center are housed in a wonderful Ambulatory Clinical Care building designed so that patients can receive appropriate retinal photos, foot care, diabetes education, and other routine medical care at one location. The position will be highly competitive with regard to start-up funds, laboratory space (if needed) and salary. The Center seeks an individual of outstanding research potential relating to diabetes pathophysiology or treatment. Applicants should send curriculum vitae, statement of research interests, and names and addresses of three references to Drs. Harlan and Greiner  c/o Patricia Cannon.

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