Projects - HIRN

A Stress-Induced Vicious Cycle in the Development of T1D View
Alternative RNA splicing events contribute to the onset of islet dysfunction in T1D View
BioStructure & Function Team Leader View
Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression View
Developing a Platform Technology for β-Cell-Targeted Drug Delivery View
Development of platforms for beta cell-specific delivery and ligand discovery View
Dissecting Transcriptomics and Epigenomic Signatures of Immune Cells in T1D View
GABP is a novel regulator of beta cell metabolism and proliferation View
Gene Therapy for Diabetes View
Image based spatial transcriptomics to identify Beta Cell phenotypes in Type 1 Diabetes View
Integrated Stress Response in Human Islets during Early T1D View
Investigation of the Role of HNF1A in Increasing Susceptibility to Type 1 Diabetes View
iSTAR Tregs View
Lactate-mediated Metabolic Reprogramming of Beta Cells in T1D Contributes to their Enhanced Plasticity and Dedifferentiation View
Metabolic requirements of pancreatic beta cell proliferation View

Biomarkers for Diabetes using Stem Cell-derived Beta Cells View
Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker) View
Defining Islet Heterogeneity Using Single Islet Transcriptomics View
Development of an Early Diagnostic Biomarker and Novel Treatment Strategy for T1D View
Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes View
Elucidating the Human Beta Cell Translatome in Health and Disease View
Epigenetic, Protein, and Cellular Biomarkers of Beta Cell Function in T1D View
Functional and Molecular Characterization of the Human Islet Interferon Alpha Response View
High-Resolution Analysis of Juvenile Human Pancreas Maturation View
Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes View
Mapping the Association of Beta Cell Longevity and Senescence in T1D View
Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms View
Non-invasive Diagnosis of Human Beta Cell Damage and Death View
Real-time in vivo Analysis of Islet Redox Dynamics View
Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis View
Single Cell Resolution of Omics Analysis of T1D Islets View
Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging View

Projects - CBDS