Human insulin as both antigen and protector in type 1 diabetes

Consortia: CMAI

Amdare NP, Shultz LD, Greiner DL, DiLorenzo TP.
Eur J Immunol. 2024 May 22:e2350949. doi: 10.1002/eji.202350949. Online ahead of print. PMID:38778498

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LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes Inhibition of the eukaryotic initiation factor-2-α kinase PERK decreases risk of autoimmune diabetes in mice Enhancing Therapeutic Insulin Transport from Macroencapsulated Islets Using Sub-Minute Pressure at Physiological Levels Roadblocks confronting widespread dissemination and deployment of Organs on Chips AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model Do We Need a New Hypothesis for KATP Closure in β-Cells? Distinguishing the Baby From the Bathwater Unfolding emergency calls stress granules to the ER
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