Presentation by:    Wendell Lim, PhD, University of California, San Francisco

Topics discussed:

• Immune destruction of islets in T1D requires therapeutic strategies to protect and/or replace islets
• Expanding set of synthetic biology tools for precision engineering of cell interactions/functions that could be applied to T1D
• Engineering synthetic immune suppressor cells that can sense and protect islets through local tissue-targeted suppression
• Developing new ways to steer organoid formation that could be used generate islets