Presentation by:  Marlie Maestas, PhD Candidate, Washington University School of Medicine

Topics discussed:

• Analysis of single-cell sequencing of endoplasmic reticulum (ER) and inflammatory stressed primary human islets
• Unique Islet Cell type responses identified
• Exocrine and endocrine tissues have differential responses to stress
• Changes in chromatin accessibility associated with type one diabetes
• CIB1 identified as a key regulator of islet function and stress response