Active Projects

  • A microwell perfusion plate for manufacturing and testing Islet-like clusters View
  • Beta-cells 1st Responders and Functional Paracrine Networks in Healthy and Diabetic Human Islets View
  • Dissecting Chimeric Antigen Receptor Function in Human Regulatory T Cells View
  • GABP is a novel regulator of beta cell metabolism and proliferation View
  • Gene regulatory programs driving metabolic maturation of human pluripotent stem cell derived β-cells View
  • Identification of Novel Regulatory Mechanisms Driving Human Beta-Cell Maturation and Function View
  • Image based spatial transcriptomics to identify Beta Cell phenotypes in Type 1 Diabetes View
  • Investigation of the Role of HNF1A in Increasing Susceptibility to Type 1 Diabetes View
  • Measuring Islet-wide Function with Soft Integrated Nanoelectronics View
  • Metabolic requirements of pancreatic beta cell proliferation View
  • Positron emission tomography to characterize beta cell mass in individuals from multiple stages in the progression of type 1 diabetes View

Closed Projects

  • Changes in Human Islet Microvasculature during Type 1 Diabetes View
  • Elucidating the Human Beta Cell Translatome in Health and Disease View
  • Functional and Molecular Characterization of the Human Islet Interferon Alpha Response View
  • HLA multimer based characterization of Islet Resident CD4+ T Cells that Target Beta Cell Epitopes and Neo-epitopes View
  • Identification of the Cognate Epitopes of Autoreactive T Cells in T1D View
  • In vivo Effects of Physical Exercise on Human Islet Structure and Function View
  • Mapping the Association of Beta Cell Longevity and Senescence in T1D View
  • Neuromodulation for Type 1 Diabetes: Harnessing Sensory Innervation to Promote Regeneration and Function of Insulin-Producing Cells View
  • On the Plasticity of Beta-cell Antigen Recognition by Diabetogenic CD8 T cells View
  • Primary Cilia in Human T1D Pancreas View
  • Real-time in vivo Analysis of Islet Redox Dynamics View
  • Targeting DNA Hydroxymethylation to Promote Human Beta Cell Function View
  • The SIRP:CD47 Signaling Pathway in Pancreatic Beta-Cell Survival View
  • Vascular Network-mimetic Oxygen-Transporting Mesh for Islet Graft View


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