Announcements

HIRN Webinar: Circulating Extracellular Vesicles in Type One Diabetes

Click HERE to view YouTube recording of the webinar.

Thursday, October 24, 2024 (1:00 pm Eastern / 10:00 am Pacific)

Presentations by:   
Raghu Mirmira, MD, PhD, University of Chicago
Ernesto Nakayasu, PhD, Pacific Northwest National Laboratory
Emily Sims, MD, Indiana University School of Medicine

Topics discussed:
– A highly sensitive proteomics platform enables extracellular vesicle (EV) analysis from minimal plasma volumes.
– Proteomics analysis of auto-antibody positive plasma identifies potential biomarkers.
– Beta cell EVs carrying PD-L1 reduce CD8 T cell activation.
– Plasma EV PD-L1 cargo correlates with residual C-peptide in AAb+ individuals and in individuals with new-onset T1D

 

 

Announcements New Awards: HIRN Human Pancreas Analysis Consortium (HPAC) NIH NIDDK New Investigator Gateway Award Recipients (2026) HIRN Associate Membership HIRN Data Scholars Awards HIRN Webinar: Identification of Unique Cell Type Responses in Pancreatic Islets to Stress HIRN Webinar: Circulating Extracellular Vesicles in Type One Diabetes HIRN 2025 “Changing the Course in Type 1 Diabetes” Meeting: January 13 – 14, 2025 HIRN Webinar: Emerging role for tissue-specific extracellular vesicles in disease diagnosis: implications for Type 1 Diabetes HIRN Webinar: “Microfluidic Models for Types 1 Diabetes on a Chip” HIRN Webinar: “Extensive Cell Turnover During Postnatal Pancreas Growth” HIRN Webinar: “Synthetic Biology and Type 1 Diabetes: New Approaches to Protect and Construct Islets” NIH NIDDK New Investigator Gateway Award Recipients (Nov 2023) HIRN Webinar: “A Roadmap to Restoring Tolerance in Type 1 Diabetes: CAR Tregs & Beyond” HIRN Webinar: “RNA Process in Metabolic Tissues” HIRN Webinar: “Update on Type 1 Diabetes (T1D) Screening & Disease Modifying Therapies” Webinar: “Stem Cell-based Platforms to Model Human Autoimmune Diabetes” HIRN Funding Opportunity: Pancreas Knowledgebase Program (PanKbase)
(RFA-DK-22-018)
Webinar: Reprogramming Human Regulatory T Cells to Quell Autoimmunity and Transplant Rejection January 2022 Webinar: “mRNA Modifications in Islet Biology” Gateway Investigator RFA HIRN Catalyst Initaitive (2021) Office Hours
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