Author: Layla Rouse, MS

HIRN 2018 New Investigator Award Recipients

Posted on | by Layla Rouse, MS

Recipients of the HIRN 2018 New Investigator Awards

Seven investigators were selected to carryout bold and highly innovative new research approaches to biological problems under current investigation in HIRN.  They will join their respective consortium conference calls and attend the HIRN Annual Investigator Meeting.

New Awards: RFA-DK-17-003: Therapeutic Targeting of the Human Islet Environment (UC4)

Posted on | by Layla Rouse, MS

New HIRN Grants from RFA-DK-17-003: Therapeutic Targeting of the Human Islet Environment (UC4)

CTAR

Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity

UC4 DK116241

Paolo Serafini (Univ. of Miami)*
Midhat Abdulreda (Univ. of Miami)
Co-Investigator: Peter Buchwald (Univ. of Miami)
Co-Investigator: Camillo Ricordi (Univ. of Miami)
Co-Investigator: Natasa Strbo (Univ. of Miami)

CTAR

Therapeutic Targeting of the Human Islet Environment

UC4 DK116264

Jeffrey Bluestone (Univ. California, San Francisco)*
Wendell Lim (Univ. California, San Francisco)
Co-Investigator: Qizhi Tang (Univ. California, San Francisco)
Co-Investigator: Kole Roybal (Univ. California, San Francisco)

CTAR

CAR T Cell Targeting of Human Islets

UC4 DK116252

Seung Kim (Stanford Univ.)*
Everett Meyer (Stanford Univ)
Co-Investigator: Philip Streeter (Oregon Health & Science Univ.)

CTAR

Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells

UC4 DK116255

Amit Choudhary (Broad Institute)*
Bridget Wagner (Broad Institute)
Rohit Kulkarni (Joslin Diabetes Center)

* Denotes Contact PI

RFA-DK-17-004: Competitive Collaborative Projects for Human Islet Biology (UC4)

Posted on | by Layla Rouse, MS

New Awards: RFA-DK-17-004: Competitive Collaborative Projects for Human Islet Biology (UC4)

CTAR

Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling

UC4 DK116280

Qiao Zhou (Harvard Univ.)*
Stephan Kissler (Joslin Diabetes Center)

CMAI

Human Islet-Infiltrating T Cell Biology: Reactivity, Structure and Function

UC4 DK116284

Sally Kent (Univ. of Massachusetts Medical School)*
David Harlan (Univ. of Massachusetts Medical School)
Lawrence Stern (Univ. of Massachusetts Medical School)
Co-Investigator: Dirk Homann (Mount Sinai School of Medicine)

CHIB

Modular Monitoring of Hormone Release from Human Islets

UC4 DK116283

Michael Roper (Florida State Univ.)*
Christopher Hughes (Univ. of California, Irvine)
Ryan White (Univ. of Cincinatti)

CBDS

Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms

UC4 DK116274

Desmond Schatz (Univ. Florida)*
Yuval Dor (Hebrew Univ. of Jerusalem)
Carla Greenbaum (Benaroya Research Institute at Virginia Mason)

CBDS

Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes

UC4 DK116278

Rohit Kulkarni (Joslin Diabetes Center)*
Chuan He (Univ. of Chicago)

CBDS

Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes

UC4 DK116271

Klaus Kaestner (Univ. of Pennsylvania)*
Yuval Dor (Hebrew Univ. of Jerusalem)
Ali Naji (Univ. of Pennsylvania)

* Denotes Contact PI