Regulatory T cell homeostasis: Requisite signals and implications for clinical development of biologics

Consortia: CMAI, Opportunity Pool Projects

Skartsis N, Muller YD, Ferreira LMR.
Clin Immunol. 2023 Jan;246:109201. doi: 10.1016/j.clim.2022.109201. Epub 2022 Dec 5. PMID:36470337

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LONP1 regulation of mitochondrial protein folding provides insight into beta cell failure in type 2 diabetes Inhibition of the eukaryotic initiation factor-2-α kinase PERK decreases risk of autoimmune diabetes in mice Enhancing Therapeutic Insulin Transport from Macroencapsulated Islets Using Sub-Minute Pressure at Physiological Levels Roadblocks confronting widespread dissemination and deployment of Organs on Chips AAV Capsid Screening for Translational Pig Research Using a Mouse Xenograft Liver Model Do We Need a New Hypothesis for KATP Closure in β-Cells? Distinguishing the Baby From the Bathwater Unfolding emergency calls stress granules to the ER
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