Baseline Insulin Secretion Determines Response to Abatacept in Stage 1 Type 1 Diabetes

Consortia: CBDS

Galderisi A, Carr ALJ, Taylor P, Bonet J, Cuthbertson D, Sosenko J, Sims EK, Evans-Molina C, Dalla Man C, Ismail HM, Nathan B, Petrelli A, Senior P, Sherr JL, Herold KC, Russell WE, Moran A, Dayan C.
Diabetes. 2026 Jan 20;75(2):229-240. doi: 10.2337/db25-0801. PMID: 41237315 

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and proteomics: from artifacts to elucidation of biological functions Histopathology-based protein multiplex generation using deep learning The integrated stress response promotes macrophage inflammation and migration in autoimmune diabetes Increased longevity of circulating human IgG in an NSG Fc gamma receptor-1 deficient humanized mouse model From Human to Mouse and Back Again: Genetic and Genomic Ta(i)les of Islet Dysfunction in Type 2 Diabetes Receptor-tethered orthogonal IL-2 enhances regulatory T cell therapy Divergent Cell-Type Specific Hypoxia Responses in Human Stem Cell-Derived and Primary Islets Spatially Bound Functional Heterogeneity Drives Modular Organization in Beta Cell Networks The pathophysiology, presentation and classification of Type 1 diabetes The Heterogeneity of Type 1 Diabetes: Implications for Pathogenesis, Prevention, and Treatment-2024 Diabetes, Diabetes Care, and Diabetologia Expert Forum Integrative single-cell multi-omics profiling of human pancreatic 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