cytoviewer: an R/Bioconductor package for interactive visualization and exploration of highly multiplexed imaging data.

Consortia: CBDS

Meyer L, Eling N, Bodenmiller B.
BMC Bioinformatics. 2024 Jan 3;25(1):9. doi: 10.1186/s12859-023-05546-z.  PMID: 38172724

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restrain the differentiation and maturation of human stem cell-derived β cells CNTools: A computational toolbox for cellular neighborhood analysis from multiplexed images Interruption of glucagon signaling augments islet non-alpha cell proliferation in SLC7A2- and mTOR-dependent manners Single cell multiome profiling of pancreatic islets reveals physiological changes in cell type-specific regulation associated with diabetes risk Exploring new frontiers in type 1 diabetes through advanced mass-spectrometry-based molecular measurements Single-cell multi-omic and spatial profiling of human kidneys implicates the fibrotic microenvironment in kidney disease progression Sodium butyrate prevents cytokine-induced β-cell dysfunction through restoration of stromal interaction molecule 1 expression and activation of store-operated calcium entry 12-Lipoxygenase inhibition suppresses islet immune and inflammatory responses and delays autoimmune diabetes in human gene replacement mice Everything You Wanted to Know About Pancreatic Ducts But Didn’t Know Where to Look No evidence for persistent enteroviral B infection of pancreatic islets in type 1 diabetic and pre-diabetic patients from RNA-Seq data Diabetes mellitus-Progress and opportunities in the evolving epidemic Atypical KCNQ1/Kv7 channel function in a neonatal diabetes patient: Hypersecretion preceded the failure of pancreatic β-cells CD39 delineates chimeric antigen receptor regulatory T cell subsets with distinct cytotoxic & regulatory functions against human islets Single-cell transcriptomic profiling of human pancreatic islets reveals genes responsive to glucose exposure over 24 h Identification of unique cell type responses in pancreatic islets to stress The Chicken or the Egg Dilemma: Understanding the Interplay between the Immune System and the β Cell in Type 1 Diabetes HumanIslets: An integrated platform for human islet data access and analysis A metabolic redox relay supports ER proinsulin export in pancreatic islet 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