Cryopreservation and post-thaw characterization of dissociated human islet cells

Consortia: HPAC

Marquez-Curtis LA, Dai XQ, Hang Y, Lam JY, Lyon J, Manning Fox JE, McGann LE, MacDonald PE, Kim SK, Elliott JAW.
PLoS One. 2022 Jan 26;17(1):e0263005. doi: 10.1371/journal.pone.0263005. eCollection 2022. PMID:35081145

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Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells β-Cell Function and Insulin Sensitivity in Youth With Early Type 1 Diabetes From a 2-Hour 7-Sample OGTT Strong ubiquitous micro-promoters for recombinant adeno-associated viral vectors Extrahepatic transplantation of 3D cultured stem cell-derived islet organoids on microporous scaffolds Single-cell expression profiling of islets generated by the Human Pancreas Analysis Program Origin, phenotype and autoimmune potential of T cells in human immune system mice receiving neonatal human thymus tissue Interpreting non-coding disease-associated human variants using single-cell epigenomics Human pluripotent-stem-cell-derived organoids for drug discovery and evaluation Developments in stem cell-derived islet replacement therapy for treating type 1 diabetes Rediscovering Primary Cilia in Pancreatic Islets The human α cell in health and disease Stomach-derived human insulin-secreting organoids restore glucose homeostasis Deletion of the Unfolded Protein Response Transducer IRE1α Is Detrimental to Aging Photoreceptors and to ER Stress-Mediated Retinal Degeneration Ca(2+) Release or Ca(2+) Entry, that is the Question: What Governs Ca(2+) Oscillations in Pancreatic Beta Cells?
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