Skip to content
Login
Menu
About
Overview
Partners
Frequently Asked Questions (FAQs)
Logos
Annual Investigator Meeting
Members
Participants
Coordinating Groups
Trans-Network Committee
Enhancement Center (HIREC)
COMPLETED: Consortium on Targeting and Regeneration (CTAR)
Overview
Projects
Participants
Close
Our Research
Consortium on Beta Cell Death and Survival (CBDS)
Overview
Projects
Participants
Consortium on Human Islet Biometrics (CHIB)
Overview
Projects
Participants
Consortium on Modeling Autoimmune Interactions (CMAI)
Overview
Projects
Participants
Human Pancreas Analysis Consortium (HPAC)
Overview
Projects
Participants
Human Pancreas Analysis Program (HPAP)
Overview
Projects
PancDB
New Investigators
Overview
Projects
Participants
Pancreas Knowledgebase Program (PanKbase)
Overview
Projects
Participants
Close
Papers
Reports
All HIRN Publications
Review Series
Publications of Interest
Close
Resources
HIRN Analytics
Resource Browser
HPAP PancDB
IIDP
nPOD
Pancreatlas
Webinar Series
Tips for the NIH Data Sharing Plan
Close
News
Meetings
Awards
Newsletters
Announcements
Close
Funding
Jobs
Contact
Search
Search
Login
Biological controls for standardization and interpretation of adaptive immune receptor repertoire profiling
Consortia:
HPAC
All
High affinity chimeric antigen receptor signaling induces an inflammatory program in human regulatory T cells
Islet autoantibodies as precision diagnostic tools to characterize heterogeneity in type 1 diabetes: a systematic review
Cyborg islets: implanted flexible electronics reveal principles of human islet electrical maturation
miR-146a-5p mediates inflammation-induced β cell mitochondrial dysfunction and apoptosis
Proinsulin folding and trafficking defects trigger a common pathological disturbance of endoplasmic reticulum homeostasis
Diabetes as a Pancreatic Microvascular Disease-A Pericytic Perspective
Interferons are key cytokines acting on pancreatic islets in type 1 diabetes
Redox regulation of m(6)A methyltransferase METTL3 in β-cells controls the innate immune response in type 1 diabetes
Regulation of β-cell death by ADP-ribosylhydrolase ARH3 via lipid signaling in insulitis
Immuno-Scanning Electron Microscopy of Islet Primary Cilia
Reduction of chemokine CXCL9 expression by omega-3 fatty acids via ADP-ribosylhydrolase ARH3 in MIN6 insulin-producing cells
A Composite Biomarker Signature of Type 1 Diabetes Risk Identified via Augmentation of Parallel Multi-Omics Data from a Small Cohort
Comparative and integrative single cell analysis reveals new insights into the transcriptional immaturity of stem cell-derived β cells
DNA methylation-based assessment of cell composition in human pancreas and islets
A fast and sensitive size-exclusion chromatography method for plasma extracellular vesicle proteomic analysis
Local dialogues between the endocrine and exocrine cells in the pancreas
KD025 is a casein kinase 2 inhibitor that protects against glucolipotoxicity in beta cells
SliceChip: a benchtop fluidic platform for organotypic culture and serial assessment of human and rodent pancreatic slices
Histone Deacetylase Inhibitors Prevent Cytokine-Induced β Cell Dysfunction Through Restoration of Stromal Interaction Molecule 1 Expression and Activation of Store-Operated Calcium Entry
RedRibbon: A new rank-rank hypergeometric overlap for gene and transcript expression signatures
Conformational plasticity of RAS Q61 family of neoepitopes results in distinct features for targeted recognition
NADPH Oxidase 2-Derived Reactive Oxygen Species Promote CD8+ T Cell Effector Function
Protection of β cells against pro-inflammatory cytokine stress by the GDF15-ERBB2 signaling
How to Test Human CAR T Cells in Solid Tumors, the Next Frontier of CAR T Cell Therapy
Redirecting Human Conventional and Regulatory T Cells Using Chimeric Antigen Receptors
Disrupted RNA editing in beta cells mimics early-stage type 1 diabetes
RFX6 maintains gene expression and function of adult human islet α cells
Simplified homology-assisted CRISPR for gene editing in Drosophila
Genetic risk converges on regulatory networks mediating early type 2 diabetes
Beta-cell intrinsic dynamics rather than gap junction structure dictates subpopulations in the islet functional network
A proteomic meta-analysis refinement of plasma extracellular vesicles
Modulation of insulin secretion by RBFOX2-mediated alternative splicing
K(ATP) channel activity and slow oscillations in pancreatic beta cells are regulated by mitochondrial ATP production
A versatile pumpless multi-channel fluidics system for maintenance and real-time functional assessment of tissue and cells
Checkpoint kinase 2 controls insulin secretion and glucose homeostasis
HNF1α maintains pancreatic α and β cell functions in primary human islets
Stress-induced β cell early senescence confers protection against type 1 diabetes
Human Pseudoislet System for Synchronous Assessment of Fluorescent Biosensor Dynamics and Hormone Secretory Profiles
Inhibition of polyamine biosynthesis preserves β cell function in type 1 diabetes
Dynamic scRNA-seq of live human pancreatic slices reveals functional endocrine cell neogenesis through an intermediate ducto-acinar stage
An integrative single-cell multi-omics profiling of human pancreatic islets identifies T1D associated genes and regulatory signals
A bright future for glucagon and alpha cell biology
Exocrine pancreas in type 1 and type 2 diabetes: different patterns of fibrosis, metaplasia, angiopathy, and adiposity
Benchmarking algorithms for joint integration of unpaired and paired single-cell RNA-seq and ATAC-seq data
Functional interrogation of twenty type 2 diabetes-associated genes using isogenic hESC-derived β-like cells
HLA3DB: comprehensive annotation of peptide/HLA complexes enables blind structure prediction of T cell epitopes
Deconstructing the integrated oscillator model for pancreatic β-cells
The leptin receptor has no role in delta-cell control of beta-cell function in the mouse
Transcriptome and secretome profiling of sensory neurons reveals sex differences in pathways relevant to insulin sensing and insulin secretion
Insulin-like Growth Factor-1 Synergizes with IL-2 to Induce Homeostatic Proliferation of Regulatory T Cells
Follow
×
Follow
us on our social networks.
Email:
hirnec@coh.org