Active Projects

  • A microwell perfusion plate for manufacturing and testing Islet-like clusters View
  • Advanced Pancreatic-immune Organoid Models of Type 1 Diabetes Subtypes and Therapeutic Responses View
  • Dissecting Chimeric Antigen Receptor Function in Human Regulatory T Cells View
  • Gene regulatory programs driving metabolic maturation of human pluripotent stem cell derived β-cells View
  • Identification of Novel Regulatory Mechanisms Driving Human Beta-Cell Maturation and Function View
  • Measuring Islet-wide Function with Soft Integrated Nanoelectronics View
  • Models to Study the Synergy between Autoimmunity and Metabolism in T1D View
  • Stem Cell-based Modeling of Type 1 Diabetes to Accelerate Translation of Therapies View
  • Studying the Mechanisms of Initiation and Progression of Beta Cell Death in T1D View
  • Tregs as Vehicles for Targeted Delivery of Therapeutic Payload to Human Islets View
  • Understanding Thymic Epithelial and Hematopoietic Stem Cell-intrinsic Immune Abnormalities Driving T1D in Optimized HIS Mouse Models View
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