Publications of Interest

Publication Date	Publication
04/12/2018	Synaptotagmin 4 Regulates Pancreatic β Cell Maturation by Modulating the Ca²⁺Sensitivity of Insulin Secretion Vesicles. Huang C, Walker EM, Dadi PK, Hu R, Xu Y, Zhang W, Sanavia T, Mun J, Liu J, Nair GG, Tan HYA, Wang S, Magnuson MA, Stoeckert CJ Jr., Hebrok M, Gannon M, Han W, Stein R, Jacobson DA, Gu G. Dev Cell. 2018 Apr 12. pii: S1534-5807(18)30233-8. PMID: 29656931
04/17/2018	Molecular pathways for antigenic peptide generation by ER aminopeptidase 1. Mpakali A, Maben Z, Stern LJ, Stratikos E. Mol Immunol. 2018 Apr 17. pii: S0161-5890(18)30105-6. PMID: 29678301
05/01/2018	Dimensions of immunologic memory. Homann D, Kedl RM. Immunol Rev. 2018 May;283(1):5-6. PMID: 29664575
04/30/2018	Revealing the specificity of regulatory T cells in murine autoimmune diabetes. Spence A, Purtha W, Tam J, Dong S, Kim Y, Ju CH, Sterling T, Nakayama M, Robinson WH, Bluestone JA, Anderson MS, Tang Q. Proc Natl Acad Sci U S A. 2018 Apr 30. pii: 201715590. PMID: 29712852
04/25/2018	Design of a vascularized synthetic poly(ethylene glycol) macroencapsulation device for islet transplantation. Weaver JD, Headen DM, Hunckler MD, Coronel MM, Stabler CL, García AJ. 2018 Apr 25;172:54-65. doi: 10.1016/j.biomaterials.2018.04.047.PMID: 29715595
11/01/2017	Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials. Nathan BM, Boulware D, Geyer S, Atkinson MA, Colman P, Goland R, Russell W, Wentworth JM, Wilson DM, Evans-Molina C, Wherrett D, Skyler JS, Moran A, Sosenko JM; Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups. Diabetes Care. 2017 Nov;40(11):1494-1499. PMID: 28860125
10/01/2017	Circulating B cells in type 1 diabetics exhibit fewer maturation-associated phenotypes. Hanley P, Sutter JA, Goodman NG, Du Y, Sekiguchi DR, Meng W, Rickels MR, Naji A, Luning Prak ET. Clin Immunol. 2017 Oct;183:336-343. PMID: 28951327
05/15/2018	Genetic Models of Macrophage Depletion. Hua L, Shi J, Shultz LD, Ren G. Methods Mol Biol. 2018;1784:243-258. doi: 10.1007/978-1-4939-7837-3_22. PMID: 29761404
05/16/2018	Strength in Numbers: Opportunities for Enhancing the Development of Effective Treatments for Type 1 Diabetes-The TrialNet Experience. Greenbaum CJ, Speake C, Krischer J, Buckner J, Gottlieb PA, Schatz DA, Herold KC, Atkinson MA. Diabetes. 2018 May 16. pii: db180065. PMID: 29769238
05/01/2018	Pancreas regeneration. Zhou Q, Melton DA. Nature. 2018 May;557(7705):351-358. PMID: 29769672
04/30/2018	Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells. Odorico J, Markmann J, Melton D, Greenstein J, Hwa A, Nostro C, Rezania A, Oberholzer J, Pipeleers D, Yang L, Cowan C, Huangfu D, Egli D, Ben-David U, Vallier L, Grey ST, Tang Q, Roep B, Ricordi C, Naji A, Orlando G, Anderson DG, Poznansky M, Ludwig B, Tomei A, Greiner DL, Graham M, Carpenter M, Migliaccio G, D’Amour K, Hering B, Piemonti L, Berney T, Rickels M, Kay T, Adams A. Transplantation. 2018 Apr 30. doi: 10.1097/TP. PMID: 29781950
05/11/2018	Humanised recombinant antibody fragments bind human pancreatic islet cells. Buenafe AC, Streeter PR. J Immunol Methods. 2018 May 11. pii: S0022-1759(18)30068-1. PMID: 29758224
06/01/2018	Immune Recognition of β-Cells: Neoepitopes as Key Players in the Loss of Tolerance. James EA, Pietropaolo M, Mamula MJ. Diabetes. 2018 Jun;67(6):1035-1042. PMID: 29784651
06/01/2018	Identification and characterization of HIV-specific resident memory CD8₊ T cells in human lymphoid tissue. Buggert M, Nguyen S, Salgado-Montes de Oca G, Bengsch B, Darko S, Ransier A, Roberts ER, Del Alcazar D, Brody IB, Vella LA, Beura L, Wijeyesinghe S, Herati RS, Del Rio Estrada PM, Ablanedo-Terrazas Y, Kuri-Cervantes L, Sada Japp A, Manne S, Vartanian S, Huffman A, Sandberg JK, Gostick E, Nadolski G, Silvestri G, Canaday DH, Price DA, Petrovas C, Su LF, Vahedi G, Dori Y, Frank I, Itkin MG, Wherry EJ, Deeks SG, Naji A, Reyes-Terán G, Masopust D, Douek DC, Betts MR. Sci Immunol. 2018 Jun 1;3(24). PMID: 29858286
06/01/2018	Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges. Sneddon JB, Tang Q, Stock P, Bluestone JA, Roy S, Desai T, Hebrok M.Cell Stem CellPMID: 29859172
03/29/2018	Establishment of Human Pluripotent Stem Cell-derived Pancreatic β-like cells in the Mouse Pancreas. Ma H, Wert KJ, Shvartsman D, Melton DA, Jaenisch R. Proc Natl Acad Sci U S A. 2018 Mar 29. pii: 201702059. PMID: 29599125
04/05/2018	Human MAIT Cells Exit Peripheral Tissues and Recirculate via Lymph in Steady State Conditions Voillet V, Buggert M, Slichter CK, Berkson JD, Mair F, Addison MM, Dori Y, Nadolski G, Itkin MG, Gottardo R, Betts MR, Prlic M. JCI Insight. 2018 Apr 5;3(7). pii: 98487.
03/13/2018	Single-Cell Mass Spectrometry Reveals Changes in Lipid and Metabolite Expression in RAW 264.7 Cells upon Lipopolysaccharide Stimulation. Yang B, Patterson NH, Tsui T, Caprioli RM, Norris JL. J Am Soc Mass Spectrom. 2018 Mar 13. doi: 10.1007/s13361-018-1899-9.PMID: 29536413
03/06/2018	Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point. Rodriguez-Diaz R, Molano RD, Weitz JR, Abdulreda MH, Berman DM, Leibiger B, Leibiger IB, Kenyon NS, Ricordi C, Pileggi A, Caicedo A, Berggren PO. Cell Metab. 2018 Mar 6;27(3):549-558.e4. doi: 10.1016/j.cmet.2018.01.015. PMID: 29514065
03/01/2018	Signaling between pancreatic β-cells and macrophages via S100 calcium-binding protein A8 exacerbates β-cell apoptosis and islet inflammation. Inoue H, Shirakawa J, Togashi Y, Tajima K, Okuyama T, Kyohara M, Tanaka Y, Orime K, Saisho Y, Yamada T, Shibue K, Kulkarni RN, Terauchi Y. J Biol Chem. 2018 Mar 1. pii: jbc.M117.809228. PMID: 29496993
03/02/2018	Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes. Sockolosky JT, Trotta E, Parisi G, Picton L, Su LL, Le AC, Chhabra A, Silveria SL, George BM, King IC, Tiffany MR, Jude K, Sibener LV, Baker D, Shizuru JA, Ribas A, Bluestone JA, Garcia KC. Science. 2018 Mar 2;359(6379):1037-1042. PMID: 29496879
12/05/2017	MAIT Cells:A Link between Gut Integrity and Type 1 Diabetes. Gülden E, Palm N, Herold KC. Cell Metab. 2017 Dec 5;26(6):813-815.PMID: 29211981
11/09/2017	A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells. Balhuizen A, Massa S, Mathijs I, Turatsinze JV, De Vos J, Demine S, Xavier C, Villate O, Millard I, Egrise D, Capito C, Scharfmann R, In’t Veld P, Marchetti P, Muyldermans S, Goldman S, Lahoutte T, Bouwens L, Eizirik DL, Devoogdt N. Sci Rep. 2017 Nov 9;7(1):15130. PMID: 29123178
11/28/2017	Combining Machine Learning and Nanofluidic Technology To Diagnose Pancreatic Cancer Using Exosomes. Ko J, Bhagwat N, Yee SS, Ortiz N, Sahmoud A, Black T, Aiello NM, McKenzie L, O’Hara M, Redlinger C, Romeo J, Carpenter EL, Stanger BZ, Issadore D. ACS Nano. 2017 Nov 28;11(11):11182-11193. PMID: 29019651
10/03/2016	Advances in β cell replacement and regeneration strategies for treating diabetes Benthuysen JR, Carrano AC, Sander M. J Clin Invest. 2016 Oct 3;126(10):3651-3660. doi: 10.1172/JCI87439. Review. PMID: 27694741
09/01/2016	Effects of ageing and senescence on pancreatic β-cell function. Helman A, Avrahami D, Klochendler A, Glaser B, Kaestner KH, Ben-Porath I, Dor Y. Diabetes Obes Metab. 2016 Sep;18 Suppl 1:58-62. doi: 10.1111/dom.12719. Review PMID: 27615132
05/10/2016	Generation of stem cell-derived β-cells from patients with type 1 diabetes Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA. Nat Commun. 2016 May 10;7:11463. doi: 10.1038/ncomms11463. PMID: 27163171
12/01/2015	Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes Nakayama M, Simmons KM, Michels AW. Curr Diab Rep. 2015 Dec;15(12):113. doi: 10.1007/s11892-015-0689-z. PMID:26458384
03/02/2015	β cell death and dysfunction during type 1 diabetes development in at-risk individuals Herold KC, Usmani-Brown S, Ghazi T, Lebastchi J, Beam CA, Bellin MD, Ledizet M, Sosenko JM, Krischer JP, Palmer JP; Type 1 Diabetes TrialNet Study Group.. J Clin Invest. 2015 Mar 2;125(3):1163-73. doi: 10.1172/JCI78142. PMID: 25642774
01/08/2018	Coxsackievirus and Type 1 Diabetes Mellitus: The Wolf’s Footprints Eizirik DL, Op de Beeck A. Trends Endocrinol Metab. 2018 Jan 8. pii: S1043-2760(17)30184-4. doi: 10.1016/j.tem.2017.12.002. [Epub ahead of print] PMID: 29326001
12/13/2017	Identification of Newly Committed Pancreatic Cells in the Adult Mouse Pancreas Socorro M, Criscimanna A, Riva P, Tandon M, Prasadan K, Guo P, Humar A, Husain SZ, Leach SD, Gittes GK, Esni F. Sci Rep. 2017 Dec 13;7(1):17539. PMID: 29235528
09/14/2017	histoCAT: Analysis of Cell Phenotypes and Interactions in Multiplex Image Cytometry Data Schapiro D, Jackson HW, Raghuraman S, Fischer JR, Zanotelli VRT, Schulz D, Giesen C, Catena R, Varga Z, Bodenmiller B. Nat Methods. 2017 Sep;14(9):873-876. PMID: 28783155
12/13/2017	Growth hormone and insulin-like growth factor-I axis in type 1 diabetes Nambam B, Schatz D. Growth Horm IGF Res. 2017 Dec 13. pii: S1096-6374(17)30114-4. PMID: 29249623
07/06/2016	The Genetic Landscape of β-Cell Proliferation: Toward a Road Map Wagner BK Diabetes. 2016 Jul;65(7):1789-90. PMID: 27329954
09/25/2017	The Four-Way Stop Sign: Viruses, 12-Lipoxygenase, Islets, and Natural Killer Cells in Type 1 Diabetes Progression Semeraro ML, Glenn LM, Morris MA. Front Endocrinol (Lausanne). 2017 Sep 25;8:246. PMID: 28993759
02/09/2017	Regenerative Medicine: Interspecies Pancreas Transplants Zhou Q. Nature. 2017 Feb 9;542(7640):168-169. PMID: 28179664
02/02/2017	Reprogramming of Pancreatic Acinar Cells to Functional Beta Cells by In Vivo Transduction of a Polycistronic Construct Containing Pdx1, Ngn3, MafA in Mice Cavelti-Weder C, Zumsteg A, Li W, Zhou Q. Curr Protoc Stem Cell Biol. 2017 Feb 2;40:4A.10.1-4A.10.12. doi: 10.1002/cpsc.21. PMID: 28152182
12/20/2017	Extracellular matrix hydrogel therapies: in vivo applications and development Spang MT, Christman KL. Acta Biomater. 2017 Dec 20. pii: S1742-7061(17)30785-7. doi: 10.1016/j.actbio.2017.12.019. PMID: 29274480
12/18/2017	C-terminal modification of the insulin B:11-23 peptide creates superagonists in mouse and human type 1 diabetes Wang Y, Sosinowski T, Novikov A, Crawford F, Neau DB, Yang J, Kwok WW, Marrack P, Kappler JW, Dai S. Proc Natl Acad Sci U S A. 2017 Dec 18. pii: 201716527. doi: 10.1073/pnas.1716527115. PMID: 29255035
12/05/2017	T Cell-Mediated Beta Cell Destruction: Autoimmunity and Alloimmunity in the Context of Type 1 Diabetes Burrack AL, Martinov T, Fife BT. Front. Endocrinol., 05 December 2017. doi. 10.3389
12/14/2017	Understanding Autoimmune Diabetes through the Prism of Tri-Molecular Complex Bettini ML, Bettini M. Front Endocrinol., 14 December 2017. doi. 10.3389
12/11/2017	Oxidative Modifications in Tissue Pathology and Autoimmune Disease Yang ML, Doyle HA, Clarke SG, Herold KC, Mamula MJ. Antioxid Redox Signal. 2017 Dec 11. doi: 10.1089/ars.2017.7382. [Epub ahead of print] PMID: 29088923
12/08/2017	Deep Tissue Optical Focusing and Optogenetic Modulation with Time-reversed Ultrasonically Encoded Light Ruan H, Brake J, Robinson JE, Liu Y, Jang M, Xiao C, Zhou C, Gradinaru V, Yang C. Sci Adv. 2017 Dec 8;3(12):eaao5520. doi: 10.1126/sciadv.aao5520. eCollection 2017 Dec. PMID: 29226248
12/05/2017	Science Forum: The Human Cell Atlas Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim SK, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe’er D, Phillipakis A, Ponting CP, Quake SR, Reik W, Rozenblatt-Rosen O, Sanes JR, Satija R, Schumacher TN, Shalek AK, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton MR, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt FM, Weissman JS, Wold BJ, Xavier RJ, Yosef N; Human Cell Atlas Meeting Participants. Elife. 2017 Dec 5;6. pii: e27041. PMID: 29206104
05/08/2017	The Human Cell Atlas Aviv Regev, Sarah Teichmann, Eric S. Lander, Ido Amit, Christophe Benoist, Ewan Birney, Bernd Bodenmiller, Peter Campbell, Piero Carninci, Menna Clatworthy, Hans Clevers, Bart Deplancke, Ian Dunham, James Eberwine, Roland Eils, Wolfgang Enard, Andrew Farmer, Lars Fugger, Berthold Gottgens, Nir Hacohen, Muzlifah Haniffa, Martin Hemberg, Seung K. Kim, Paul Klenerman, Arnold Kriegstein, Ed Lein, Sten Linnarsson, Joakim Lundeberg, Partha Majumder, John Marioni, Miriam Merad, Musa Mhlanga, Martijn Nawijn, Mihai Netea, Garry Nolan, Dana Pe’er, Anthony Philipakis, Chris P. Ponting, Stephen R. Quake, Wolf Reik, Orit Rozenblatt-Rosen, Joshua R. Sanes, Rahul Satija, Ton Shumacher, Alex K. Shalek, Ehud Shapiro, Padmanee Sharma, Jay Shin, Oliver Stegle, Michael Stratton, Michael J. T. Stubbington, Alexander van Oudenaarden, Allon Wagner, Fiona M. Watt, Jonathan S. Weissman, Barbara Wold, Ramnik J. Xavier, Nir Yosef, Human Cell Atlas Meeting Participants. bioRxiv 121202; doi: https://doi.org/10.1101/121202
11/11/2017	Hospital time prior to death and pancreas histopathology: implications for future studies Kusmartseva I, Beery M, Philips T, Selman S, Jadhav P, Wasserfall C, Muller A, Pugliese A, Longmate JA, Schatz DA, Atkinson MA, Kaddis JS. Diabetologia. 2017 Nov 11. doi: 10.1007/s00125-017-4494-x. PMID: 29128936
09/01/2017	High Illicit Drug Abuse and Suicide in Organ Donors With Type 1 DiabetesZ Jacobsen LM, Haller MJ, Parish A, Gurka MJ, Levine SR, Wasserfall C, Campbell-Thompson M, Kaddis J, Pugliese A, Atkinson MA, Schatz DA. Diabetes Care. 2017 Sep;40(9):e122-e123. PMID: 28679687
12/01/2017	Tolerance in Xenotransplantation Yamada K, Sykes M, Sachs DH. Curr Opin Organ Transplant. 2017 Dec;22(6):522-528. PMID: 28937406
11/06/2017	Genome-wide Genetic and Epigenetic Analyses of Pancreatic Acinar Cell Carcinomas Reveal Aberrations in Genome Stability Jäkel C, Bergmann F, Toth R, Assenov Y, van der Duin D, Strobel O, Hank T, Klöppel G, Dorrell C, Grompe M, Moss J, Dor Y, Schirmacher P, Plass C, Popanda O, Schmezer P. Nat Commun. 2017 Nov 6;8(1):1323. PMID: 29109526
11/08/2017	LC-SRM-Based Targeted Quantification of Urinary Protein Biomarkers Gao Y, Wang H, Nicora CD, Shi T, Smith RD, Sigdel TK, Sarwal MM, Camp DG 2nd, Qian WJ. Methods Mol Biol. 2017 Nov 8. doi: 10.1007/7651_2017_93. PMID: 29116567
11/09/2017	A nanobody-based Tracer Targeting DPP6 for Non-invasive Imaging of Human Pancreatic Endocrine Cells Balhuizen A, Massa S, Mathijs I, Turatsinze JV, De Vos J, Demine S, Xavier C, Villate O, Millard I, Egrise D, Capito C, Scharfmann R, In’t Veld P, Marchetti P, Muyldermans S, Goldman S, Lahoutte T, Bouwens L, Eizirik DL, Devoogdt N. Sci Rep. 2017 Nov 9;7(1):15130. PMID: 29123178
11/01/2015	Combination Therapy Reverses Hyperglycemia in NOD Mice With Established Type 1 Diabetes Xue S, Posgai A, Wasserfall C, Myhr C, Campbell-Thompson M, Mathews CE, Brusko T, Rabinovitch A, Savinov A, Battaglia M, Schatz D, Haller M, Atkinson MA. Diabetes. 2015 Nov;64(11):3873-84. PMID: 26185279
08/01/2016	Gestational Diabetes Mellitus from Inactivation of Prolactin Receptor and MafB in Islet β-Cells Banerjee RR, Cyphert HA, Walker EM, Chakravarthy H, Peiris H, Gu X, Liu Y, Conrad E, Goodrich L, Stein RW, Kim SK. Diabetes. 2016 Aug;65(8):2331-41. PMID: 27217483
02/01/2016	Research Resource: Genetic Labeling of Human Islet Alpha Cells Pauerstein PT, Park KM, Peiris HS, Wang J, Kim SK. Mol Endocrinol. 2016 Feb;30(2):248-53. PMID: 26745668
10/31/2017	Oxidative Modifications in Tissue Pathology and Autoimmune Disease Yang ML, Doyle H, Clarke SG, Herold K, Mamula M. Antioxid Redox Signal. 2017 Oct 31. doi: 10.1089/ars.2017.7382. PMID: 29088923
10/25/2017	Immunoisolation of Murine Islet Allografts in Vascularized Sites Through Conformal Coating with Polyethylene Glycol Manzoli V, Villa C, Bayer AL, Morales L, Molano RD, Torrente Y, Ricordi C, Hubbell JA, Tomei AA. Am J Transplant. 2017 Oct 25. doi: 10.1111/ajt.14547. PMID: 2906814
09/25/2017	Bioengineered AAV Capsids with Combined High Human Liver Transduction In Vivo and Unique Humoral Seroreactivity Paulk NK, Pekrun K, Zhu E, Nygaard S, Li B, Xu J, Chu K, Leborgne C, Dane AP, Haft A, Zhang Y, Zhang F, Morton C, Valentine MB, Davidoff AM, Nathwani AC, Mingozzi F, Grompe M, Alexander IE, Lisowski L, Kay MA. Mol Ther. 2017 Sep 25. pii: S1525-0016(17)30437-9. PMID: 29055620
10/27/2017	PLATO Software Provides Analytic Framework for Investigating Complexity beyond Genome-wide Association Studies Hall MA, Wallace J, Lucas A, Kim D, Basile AO, Verma SS, McCarty CA, Brilliant MH, Peissig PL, Kitchner TE, Verma A, Pendergrass SA, Dudek SM, Moore JH, Ritchie MD. Nat Commun. 2017 Oct 27;8(1):1167. PMID: 29079728
10/15/2017	Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules Yao X, Yan J, Liu K, Kim S, Nho K, Risacher SL, Greene CS, Moore JH, Saykin AJ, Shen L; Alzheimer’s Disease Neuroimaging Initiative. Bioinformatics. 2017 Oct 15;33(20):3250-3257. PMID: 28575147
10/19/2017	Cytoplasmic Chromatin Triggers Inflammation in Senescence and Cancer Dou Z, Ghosh K, Vizioli MG, Zhu J, Sen P, Wangensteen KJ, Simithy J, Lan Y, Lin Y, Zhou Z, Capell BC, Xu C, Xu M, Kieckhaefer JE, Jiang T, Shoshkes-Carmel M, Tanim KMAA, Barber GN, Seykora JT, Millar SE, Kaestner KH, Garcia BA, Adams PD, Berger SL. Nature. 2017 Oct 19;550(7676):402-406. PMID: 28976970
03/07/2017	Enhanced Spatially Resolved Proteomics Using On-Tissue Hydrogel-Mediated Protein Digestion Rizzo DG, Prentice BM, Moore JL, Norris JL, Caprioli RM. Anal Chem. 2017 Mar 7;89(5):2948-2955. PMID: 28193007
02/07/2017	ATF5 Regulates β-cell Survival During Stress Juliana CA, Yang J, Rozo AV, Good A, Groff DN, Wang SZ, Green MR, Stoffers DA. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):1341-1346. PMID: 28115692
01/06/2016	Tracking the Antibody Immunome in Type 1 Diabetes Using Protein Arrays Bian X, Wasserfall C, Wallstrom G, Wang J, Wang H, Barker K, Schatz D, Atkinson M, Qiu J, LaBaer J. J Proteome Res. 2017 Jan 6;16(1):195-203. PMID: 27690455
09/29/2017	Kinetics of Functional Beta Cell Mass Decay in a Diphtheria Toxin Receptor Mouse Model of Diabetes van Krieken PP, Dicker A, Eriksson M, Herrera PL, Ahlgren U, Berggren PO, Ilegems E. Sci Rep. 2017 Sep 29;7(1):12440. PMID: 28963457
10/19/2017	T Cells Expressing Chimeric Antigen Receptor Promote Immune Tolerance Pierini A, Iliopoulou BP, Peiris H, Pérez-Cruz M, Baker J, Hsu K, Gu X, Zheng PP, Erkers T, Tang SW, Strober W, Alvarez M, Ring A, Velardi A, Negrin RS, Kim SK, Meyer EH. JCI Insight. 2017 Oct 19;2(20). PMID: 29046484
10/23/2017	EGFR Signalling Controls Cellular Fate and Pancreatic Organogenesis by Regulating Apicobasal Polarity Löf-Öhlin ZM, Nyeng P, Bechard ME, Hess K, Bankaitis E, Greiner TU, Ameri J, Wright CV, Semb H. Nat Cell Biol. 2017 Oct 23. PMID: 29058721
07/01/2016	The Genetic Landscape of β-Cell Proliferation: Toward a Road Map Wagner BK. Diabetes. 2016 Jul;65(7):1789-90. PMID: 27329954
06/01/2016	Inhibition of DYRK1A Stimulates Human β-Cell Proliferation Dirice E, Walpita D, Vetere A, Meier BC, Kahraman S, Hu J, Dančík V, Burns SM, Gilbert TJ, Olson DE, Clemons PA, Kulkarni RN, Wagner BK. Diabetes. 2016 Jun;65(6):1660-71. PMID:26953159
04/26/2017	Synthetic Immunology: Hacking Immune Cells to Expand Their Therapeutic Capabilities Roybal KT, Lim WA. Annu Rev Immunol. 2017 Apr 26;35:229-253. doi: 10.1146/annurev-immunol-051116-052302. PMID: 28446063
10/15/2017	Tissue-specific network-based genome wide study of amygdala imaging phenotypes to identify functional interaction modules Yao X, Yan J, Liu K, Kim S, Nho K, Risacher SL, Greene CS, Moore JH, Saykin AJ, Shen L; Alzheimer’s Disease Neuroimaging Initiative. Bioinformatics. 2017 Oct 15;33(20):3250-3257. doi: 10.1093/bioinformatics/btx344. PMID: 28575147
10/12/2017	Disease-specific biases in alternative splicing and tissue-specific dysregulation revealed by multitissue profiling of lymphocyte gene expression in type 1 diabetes Newman JRB, Conesa A, Mika M, New FN, Onengut-Gumuscu S, Atkinson MA, Rich SS, McIntyre LM, Concannon P. Genome Res. 2017 Oct 12. doi: 10.1101/gr.217984.116. PMID: 29025893
10/11/2017	T Cell Receptor Profiling in Type 1 Diabetes Jacobsen LM, Posgai A, Seay HR, Haller MJ, Brusko TM. Curr Diab Rep. 2017 Oct 11;17(11):118. doi: 10.1007/s11892-017-0946-4. Review. PMID: 29022222
10/06/2017	Comprehensive Metabolomics Study To Assess Longitudinal Biochemical Changes and Potential Early Biomarkers in Nonobese Diabetic Mice That Progress to Diabetes Buchwald P, Tamayo-Garcia A, Ramamoorthy S, Garcia-Contreras M, Mendez AJ, Ricordi C. J Proteome Res. 2017 Oct 6;16(10):3873-3890. doi: 10.1021/acs.jproteome.7b00512. Epub 2017 Aug 29. PMID: 28799767
09/11/2017	A Radial Axis defined by Semaphorin to Neuropilin signaling controls pancreatic islet morphogenesis Pauerstein PT, Tellez K, Willmarth KB, Park KM, Hsueh B, Arda HE, Gu X, Aghajanian H, Deisseroth K, Epstein JA, Kim SK. Development. 2017 Sep 11. pii: dev.148684. doi: 10.1242/dev.148684. PMID: 28893946
05/31/2017	Epigenetics in Formation, Function, and Failure of the Endocrine pPancreas Golson ML,Kaestner KH. Mol Metab. 2017 May 31;6(9):1066-1076. doi: 10.1016/j.molmet.2017.05.015. eCollection 2017 Sep. Review. PMID: 28951829
09/25/2017	Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology? Greenbaum A, Jang MJ, Challis C, Gradinaru V. BMC Biol. 2017 Sep 25;15(1):87. doi: 10.1186/s12915-017-0421-3. PMID: 28946882
07/08/2017	Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis Chen C, Cohrs CM, Stertmann J, Bozsak R, Speier S. Mol Metab. 2017 Jul 8;6(9):943-957. doi: 10.1016/j.molmet.2017.06.019. eCollection 2017 Sep. Review. PMID: 28951820
07/20/2017	Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas Tritschler S, Theis FJ, Lickert H, Böttcher A. Mol Metab. 2017 Jul 20;6(9):974-990. doi: 10.1016/j.molmet.2017.06.021. eCollection 2017 Sep. Review. PMID: 28951822
05/05/2017	Interrogating islets in health and disease with single-cell technologies Carrano AC, Mulas F, Zeng C, Sander M. Mol Metab. 2017 May 5;6(9):991-1001. doi: 10.1016/j.molmet.2017.04.012. eCollection 2017 Sep. Review. PMID: 28951823
09/29/2017	Kinetics of functional beta cell mass decay in a diphtheria toxin receptor mouse model of diabetes van Krieken PP, Dicker A, Eriksson M, Herrera PL, Ahlgren U, Berggren PO, Ilegems E. Sci Rep. 2017 Sep 29;7(1):12440. doi: 10.1038/s41598-017-12124-w. PMID: 28963457
03/03/2016	Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation Ariyachet C, Tovaglieri A, Xiang G, Lu J, Shah MS, Richmond CA, Verbeke C, Melton DA, Stanger BZ, Mooney D, Shivdasani RA, Mahony S, Xia Q, Breault DT, Zhou Q. Cell Stem Cell. 2016 Mar 3;18(3):410-21. doi: 10.1016/j.stem.2016.01.003. Epub 2016 Feb 18. PMID: 26908146
09/19/2017	Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis Larsen HL, Martín-Coll L, Nielsen AV, Wright CVE, Trusina A, Kim YH, Grapin-Botton A. Nat Commun. 2017 Sep 19;8(1):605. doi: 10.1038/s41467-017-00258-4. PMID: 28928395
09/19/2017	Proteoliposome-based full-length ZnT8 self-antigen for type 1 diabetes diagnosis on a plasmonic platform Wan H, Merriman C, Atkinson MA, Wasserfall CH, Mcgrail KM, Liang Y, Fu D, Dai H. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):10196-10201. doi: 10.1073/pnas.1711169114. Epub 2017 Sep 5. PMID: 28874568
09/11/2017	Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, Herold KC, Wen L, Flavell RA. Proc Natl Acad Sci U S A. 2017 Sep 11. pii: 201705599. doi: 10.1073/pnas.1705599114. [Epub ahead of print] PMID: 28894001
09/07/2017	Mouse pancreatic islet macrophages use locally released ATP to monitor beta cell activity Weitz JR, Makhmutova M, Almaça J, Stertmann J, Aamodt K, Brissova M, Speier S, Rodriguez-Diaz R, Caicedo A. Diabetologia. 2017 Sep 7. doi: 10.1007/s00125-017-4416-y. [Epub ahead of print] PMID: 28884198
02/22/2017	A Divergent Population of Autoantigen-responsive CD4₊ T cells in infants prior to β cell autoimmunity Heninger AK, Eugster A, Kuehn D, Buettner F, Kuhn M, Lindner A, Dietz S, Jergens S, Wilhelm C, Beyerlein A, Ziegler AG, Bonifacio E. Sci Transl Med. 2017 Feb 22;9(378). pii: eaaf8848. doi: 10.1126/scitranslmed.aaf8848. PMID: 28228602
08/31/2017	Isoform-selective inhibitor of histone deacetylase 3 (HDAC3) limits pancreatic islet infiltration and protects female nonobese diabetic mice from diabetes Dirice E, Ng R, Martinez R, Hu J, Wagner FF, Holson EB, Wagner BK, Kulkarni RN. J Biol Chem. 2017 Aug 31. pii: jbc.M117.804328. doi: 10.1074/jbc.M117.804328. [Epub ahead of print] PMID: 28860191
09/05/2017	Targeted Mass Spectrometry Approach Enabled Discovery of O-Glycosylated Insulin and Related Signaling Peptides in Mouse and Human Pancreatic Islets Yu Q, Canales A, Glover MS, Das R, Shi X, Liu Y, Keller MP, Attie AD, Li L. Anal Chem. 2017 Sep 5;89(17):9184-9191. doi: 10.1021/acs.analchem.7b01926. Epub 2017 Aug 7. PMID: 28726377
08/16/2017	Reprogramming human gallbladder cells into insulin-producing β-like cells Galivo F, Benedetti E, Wang Y, Pelz C, Schug J, Kaestner KH, Grompe M. PLoS One. 2017 Aug 16;12(8):e0181812. doi: 10.1371/journal.pone.0181812. eCollection 2017. PMID: 28813430
08/30/2017	Discovery of stimulation-responsive immune enhancers with CRISPR activation Simeonov DR, Gowen BG, Boontanrart M, Roth TL, Gagnon JD, Mumbach MR, Satpathy AT, Lee Y, Bray NL, Chan AY, Lituiev DS, Nguyen ML, Gate RE, Subramaniam M, Li Z, Woo JM, Mitros T, Ray GJ, Curie GL, Naddaf N, Chu JS, Ma H, Boyer E, Van Gool F, Huang H, Liu R, Tobin VR, Schumann K, Daly MJ, Farh KK, Ansel KM, Ye CJ, Greenleaf WJ, Anderson MS, Bluestone JA, Chang HY, Corn JE, Marson A. Nature. 2017 Aug 30. doi: 10.1038/nature23875. [Epub ahead of print] PMID: 28854172
09/13/2017	β-Cell mass versus function in type 1 diabetes mellitus: truth or dare? Rodriguez-Calvo T, Atkinson M, von Herrath M. Nat Rev Endocrinol. 2017 Sep;13(9):1. doi: 10.1038/nrendo.2017.83. Epub 2017 Jul 7. No abstract available. PMID: 28685769
08/25/2016	Pancreas-enriched miRNAs are altered in the circulation of subjects with diabetes: a pilot cross-sectional study Seyhan AA, Nunez Lopez YO, Xie H, Yi F, Mathews C, Pasarica M, Pratley RE. Sci Rep. 2016 Aug 25;6:31479. doi: 10.1038/srep31479. PMID: 27558530
06/30/2017	MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells Meyerovich K, Violato NM, Fukaya M, Dirix V, Pachera N, Marselli L, Marchetti P, Strasser A, Eizirik DL, Cardozo AK. Diabetes.2017 Sep;66(9):2446-2458. doi: 10.2337/db16-1252. Epub 2017 Jun 30. PMID: 28667119
08/02/2017	Understanding and preventing type 1 diabetes through the unique working model of TrialNet Battaglia M, Anderson MS, Buckner JH, Geyer SM, Gottlieb PA, Kay TWH, Lernmark Å, Muller S, Pugliese A, Roep BO, Greenbaum CJ, Peakman M. Diabetologia. 2017 Aug 2. doi: 10.1007/s00125-017-4384-2. [Epub ahead of print] Review. PMID: 28770323
08/18/2017	Impact of blood collection and processing on peripheral blood gene expression profiling in type 1 diabetes Yip L, Fuhlbrigge R, Atkinson MA, Fathman CG. BMC Genomics. 2017 Aug 18;18(1):636. doi: 10.1186/s12864-017-3949-2. PMID: 28821222
08/16/2017	Regenerative medicine and cell-based approaches to restore pancreatic function Ellis C, Ramzy A, Kieffer TJ. Nat Rev Gastroenterol Hepatol. 2017 Aug 16. doi: 10.1038/nrgastro.2017.93. [Epub ahead of print] Review. PMID: 28811674
02/23/2017	Profiling of circulating microRNAs in children with recent onset of type 1 diabetes Erener S, Marwaha A, Tan R, Panagiotopoulos C, Kieffer TJ. JCI Insight. 2017 Feb 23;2(4):e89656. doi: 10.1172/jci.insight.89656. PMID: 28239651
03/17/2017	Tissue-specific exosome biomarkers for noninvasively monitoring immunologic rejection of transplanted tissue Vallabhajosyula P, Korutla L, Habertheuer A, Yu M, Rostami S, Yuan CX, Reddy S, Liu C, Korutla V, Koeberlein B, Trofe-Clark J, Rickels MR, Naji A. J Clin Invest. 2017 Apr 3;127(4):1375-1391. doi: 10.1172/JCI87993. Epub 2017 Mar 20. PMID: 28319051
08/07/2017	Nanoporous Immunoprotective Device for Stem-Cell-Derived β-Cell Replacement Therapy. Chang R, Faleo G, Russ HA, Parent AV, Elledge SK, Bernards DA, Allen JL, Villanueva K, Hebrok M, Tang Q, Desai TA. ACS Nano. 2017 Aug 7. doi: 10.1021/acsnano.7b01239. [Epub ahead of print] PMID: 28763191
07/07/2017	Exploring inter-organ crosstalk to uncover mechanisms that regulate β-cell function and mass Shirakawa J, De Jesus DF, Kulkarni RN. Eur J Clin Nutr. 2017 Jul;71(7):896-903. doi: 10.1038/ejcn.2017.13. Epub 2017 Mar 15. Review. PMID: 28294170
07/21/2017	Exosomes as biomarkers and therapeutic tools for type 1 diabetes mellitus. Garcia-Contreras M, Brooks RW, Boccuzzi L, Robbins PD, Ricordi C. Eur Rev Med Pharmacol Sci. 2017 Jun;21(12):2940-2956. PMID: 28682421
07/11/2017	Pancreatic β-cell protection from inflammatory stress by the endoplasmic reticulum proteins thrombospondin 1 and mesencephalic astrocyte-derived neutrotrophic factor (MANF) Cunha DA, Cito M, Grieco FA, Cosentino C, Danilova T, Ladriere L, Lindahl M, Domanskyi A, Bugliani M, Marchetti P, Eizirik DL, Cnop M. J Biol Chem. 2017 Jul 11. pii: jbc.M116.769877. doi: 10.1074/jbc.M116.769877. [Epub ahead of print] PMID: 28698383
07/31/2017	Regulatory T-cells from pancreatic lymphnodes of patients with type-1 diabetes express increased levels of microRNA miR-125a-5p that limits CCR2 expression Sebastiani G, Ventriglia G, Stabilini A, Socci C, Morsiani C, Laurenzi A, Nigi L, Formichi C, Mfarrej B, Petrelli A, Fousteri G, Brusko TM, Dotta F, Battaglia M. Sci Rep2017 Jul 31;7(1):6897. doi: 10.1038/s41598-017-07172-1.PMID: 28761107
08/08/2017	Mitigating Ischemic Injury of Stem Cell-Derived Insulin-Producing Cells after Transplant. Faleo G, Russ HA, Wisel S, Parent AV, Nguyen V, Nair GG, Freise JE, Villanueva KE, Szot GL, Hebrok M, Tang Q. Stem Cell Reports. 2017 Aug 8. pii: S2213-6711(17)30322-3. doi: 10.1016/j.stemcr.2017.07.012. PMID: 28803916
08/11/2017	A Comprehensive Metabolomics Study to Assess Longitudinal Biochemical Changes and Potential Early Biomarkers in NOD Mice that Progress to Diabetes Buchwald P, Tamayo-Garcia A, Ramamoorthy S, Garcia-Contreras M, Mendez AJ, Ricordi C. J Proteome Res. 2017 Aug 11. doi: 10.1021/acs.jproteome.7b00512. [Epub ahead of print] PMID: 28799767
07/20/2017	Plasma-derived exosome characterization reveals a distinct microRNA signature in long duration Type 1 diabetes Garcia-Contreras M, Shah SH, Tamayo A, Robbins PD, Golberg RB, Mendez AJ, Ricordi C. Sci Rep. 2017 Jul 20;7(1):5998. doi: 10.1038/s41598-017-05787-y. PMID: 28729721
07/19/2017	Pathways to clinical CLARITY: volumetric analysis of irregular, soft, and heterogeneous tissues in development and disease Hsueh B, Burns VM, Pauerstein P, Holzem K, Ye L, Engberg K, Wang AC, Gu X, Chakravarthy H, Arda HE, Charville G, Vogel H, Efimov IR, Kim S, Deisseroth Scientific Reports. 7, Article number” 5899 (2017) doi:10.1038/s41598-017-05614-4
06/01/2017	Comparative Pathogenesis of Autoimmune Diabetes in Humans, NOD Mice, and Canines: Has a Valuable Animal Model of Type 1 Diabetes Been Overlooked? O’Kell AL, Wasserfall C, Catchpole B, Davison LJ, Hess RS, Kushner JA, Atkinson MA. Diabetes. 2017 Jun;66(6):1443-1452. doi: 10.2337/db16-1551. PMID: 28533295
05/01/2017	Gotta Have GATA for Human Pancreas Development Lorberbaum DS, Sussel L. Cell Stem Cell. 2017 May 4;20(5):577-579. doi: 10.1016/j.stem.2017.04.004. PMID: 28475878
06/01/2015	Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α Ocaña GJ, Pérez L, Guindon L, Deffit SN, Evans-Molina C, Thurmond DC, Blum JS. Immunology. 2017 Jun;151(2):198-210. doi: 10.1111/imm.12723. Epub 2017 Mar 13. PMID: 28190264
04/04/2017	Targeting ABL-IRE1α Signaling Spares ER-Stressed Pancreatic β Cells to Reverse Autoimmune Diabetes Morita S, Villalta SA, Feldman HC, Register AC, Rosenthal W, Hoffmann-Petersen IT, Mehdizadeh M, Ghosh R, Wang L, Colon-Negron K, Meza-Acevedo R, Backes BJ, Maly DJ, Bluestone JA, Papa FR. Cell Metab. 2017 Apr 4;25(4):883-897.e8. doi: 10.1016/j.cmet.2017.03.018. PMID: 28380378
05/02/2017	Pseudotemporal Ordering of Single Cells Reveals Metabolic Control of Postnatal β Cell Proliferation Zeng C, Mulas F, Sui Y, Guan T, Miller N, Tan Y, Liu F, Jin W, Carrano AC, Huising MO, Shirihai OS, Yeo GW, Sander M. Cell Metab. 2017 May 2;25(5):1160-1175.e11. doi: 10.1016/j.cmet.2017.04.014. PMID: 28467932
05/13/2017	Clinical pancreatic islet transplantation Shapiro AM, Pokrywczynska M, Ricordi C. Nat Rev Endocrinol. 2017 May;13(5):268-277. doi: 10.1038/nrendo.2016.178. Epub 2016 Nov 11. Review. PMID: 27834384
06/01/2017	Mitigating hypoxic stress on pancreatic islets via in situ oxygen generating biomaterial Coronel MM, Geusz R, Stabler CL. Biomaterials. 2017 Jun;129:139-151. doi: 10.1016/j.biomaterials.2017.03.018. Epub 2017 Mar 18. PMID: 28342320
01/31/2017	Insulin and Glucagon: Partners for Life Holst JJ, Holland W, Gromada J, Lee Y, Unger RH, Yan H, Sloop KW, Kieffer TJ, Damond N, Herrera PL. Endocrinology. 2017 Jan 31. doi: 10.1210/en.2016-1748. [Epub ahead of print] PMID: 28323959
04/04/2017	Virgin Beta Cells Persist throughout Life at a Neogenic Niche within Pancreatic Islets van der Meulen T, Mawla AM, DiGruccio MR, Adams MW, Nies V, Dólleman S, Liu S, Ackermann AM, Cáceres E, Hunter AE, Kaestner KH, Donaldson CJ, Huising MO. Cell Metab. 2017 Apr 4;25(4):911-926.e6. doi: 10.1016/j.cmet.2017.03.017. PMID: 28380380
02/01/2017	All mixed up: defining roles for β-cell subtypes in mature islets Liu JS, Hebrok M. Genes Dev. 2017 Feb 1;31(3):228-240. doi: 10.1101/gad.294389.116. Review. PMID: 28270515
02/07/2017	Designing β Cells Hebrok M. Cell Metab. 2017 Feb 7;25(2):223-224. doi: 10.1016/j.cmet.2017.01.018. PMID: 28178560
01/12/2017	Artemisinins Target GABA_A Receptor Signaling and Impair α Cell Identity. Li J, Casteels T, Frogne T, Ingvorsen C, Honoré C, Courtney M, Huber KV, Schmitner N, Kimmel RA, Romanov RA, Sturtzel C, Lardeau CH, Klughammer J, Farlik M, Sdelci S, Vieira A, Avolio F, Briand F, Baburin I, Májek P, Pauler FM, Penz T, Stukalov A, Gridling M, Parapatics K, Barbieux C, Berishvili E, Spittler A, Colinge J, Bennett KL, Hering S, Sulpice T, Bock C, Distel M, Harkany T, Meyer D, Superti-Furga G, Collombat P, Hecksher-Sørensen J, Kubicek S. Cell. 2017 Jan 12;168(1-2):86-100.e15. doi: 10.1016/j.cell.2016.11.010. PMID: 27916275
09/01/2016	β-Cell replacement as a treatment for type 1 diabetes: an overview of possible cell sources and current axes of research. Vieira A, Courtney M, Druelle N, Avolio F, Napolitano T, Hadzic B, Navarro-Sanz S, Ben-Othman N, Collombat P. Diabetes Obes Metab. 2016 Sep;18 Suppl 1:137-43. doi: 10.1111/dom.12721. Review. PMID: 27615143
11/01/2016	Type 1 Diabetes Prevention: A Goal Dependent on Accepting a Diagnosis of an Asymptomatic Disease Ziegler AG, Bonifacio E, Powers AC, Todd JA, Harrison LC, Atkinson MA. Diabetes. 2016 Nov;65(11):3233-3239. PMID:27959859
01/01/2017	Future of rAAV gene therapy: Platform for RNAi, Gene Editing and Beyond Valdmanis P, Kay MA. Hum Gene Ther. 2017 Jan 10. doi: 10.1089/hum.2016.171.
01/03/2017	β Cells led astray by transcription factors and the company they keep Thompson P, Bhushan A. J Clin Invest. 2017 Jan 3;127(1):94-97. doi: 10.1172/JCI91304. PMID: 27941244
05/01/2016	Inhibition of TGF-β Signaling Promotes Human Pancreatic β-Cell Replication Dhawan S, Dirice E, Kulkarni RN, Bhushan A. Diabetes. 2016 May;65(5):1208-18. doi: 10.2337/db15-1331. PMID: 26936960
01/23/2017	Serum Trypsinogen Levels in Type 1 Diabetes Li X,Campbell-Thompson M, Wasserfall CH, McGrail K, Posgai A, Schultz AR, Brusko TM, Shuster J, Liang F, Muir A, Schatz D, Haller MJ, Atkinson MA. Diabetes Care. 2017 Jan 23. pii: dc161774. doi: 10.2337/dc16-1774. [Epub ahead of print] PMID: 28115475
06/21/2016	Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2 Yeste A, Takenaka MC, Mascanfroni ID, Nadeau M, Kenison JE, Patel B, Tukpah AM, Babon JA, DeNicola M, Kent SC, Pozo D, Quintana FJ. Sci Signal. 2016 Jun 21;9(433):ra61. doi: 10.1126/scisignal.aad0612. PMID: 27330188
12/05/2016	Engineering Therapeutic T Cells: From Synthetic Biology to Clinical Trials Esensten JH, Bluestone JA, Lim WA. Annu Rev Pathol. 2016 Dec 5. [Epub ahead of print] PMID: 27959633
12/28/2016	Human Pancreatic β Cell lncRNAs Control Cell-Specific Regulatory Networks Akerman I, Tu Z, Beucher A, Rolando DM, Sauty-Colace C, Benazra M, Nakic N, Yang J, Wang H, Pasquali L, Moran I, Garcia-Hurtado J, Castro N, Gonzalez-Franco R, Stewart AF, Bonner C, Piemonti L, Berney T, Groop L, Kerr-Conte J, Pattou F, Argmann C, Schadt E, Ravassard P, Ferrer J. Cell Metab. 2016 Dec 28. pii: S1550-4131(16)30595-2. PMID: 28041957
01/01/2017	Raising Awareness: The Need to Promote Allocation of Pancreata From Rare Nondiabetic Donors With Pancreatic Islet Autoimmunity to Type 1 Diabetes Research Burke GW 3rd, Posgai AL, Wasserfall CH, Atkinson MA, Pugliese A. Am J Transplant. 2017 Jan;17(1):306-307. doi: 10.1111/ajt.13983. No abstract available. PMID: 27460917
01/01/2017	Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Diabetologia. 2017 Jan;60(1):35-38. PMID: 27785529
12/12/2016	LIM domain-binding 1 maintains the terminally differentiated state of pancreatic β cells. Ediger BN, Lim HW, Juliana C, Groff DN, Williams LT, Dominguez G, Liu JH, Taylor BL, Walp ER, Kameswaran V, Yang J, Liu C, Hunter CS, Kaestner KH, Naji A, Li C, Sander M, Stein R, Sussel L, Won KJ, May CL, Stoffers DA. J Clin Invest. 2016 Dec 12. pii: 88016. doi: 10.1172/JCI88016. [Epub ahead of print] MID: 27941246
12/12/2016	Pancreatic β cell identity requires continual repression of non-β cell programs Gutiérrez GD, Bender AS, Cirulli V, Mastracci TL, Kelly SM, Tsirigos A, Kaestner KH, Sussel L. J Clin Invest. 2016 Dec 12. pii: 88017. doi: 10.1172/JCI88017. [Epub ahead of print] PMID: 27941248
11/11/2016	Clinical pancreatic islet transplantation Shapiro AM, Pokrywczynska M, Ricordi C. Nat Rev Endocrinol. 2016 Nov 11. doi: 10.1038/nrendo.2016.178. [Epub ahead of print] Review. PMID: 7834384
10/27/2016	Efficient generation of pancreatic β-like cells from the mouse gallbladder Wang Y, Galivo F, Pelz C, Haft A, Lee J, Kim SK, Grompe M. Stem Cell Res. 2016 Oct 27;17(3):587-596. doi: 10.1016/j.scr.2016.10.009. PMID: 27833043
10/26/2016	A Single-Cell Transcriptomic Map of the Human and Mouse Pancreas Reveals Inter- and Intra-cell Population Structure Baron M, Veres A, Wolock SL, Faust AL, Gaujoux R, Vetere A, Ryu JH, Wagner BK, Shen-Orr SS, Klein AM, Melton DA, Yanai I. Cell Syst 2016 Oct 26;3(4):346-360.e4. doi: 10.1016/j.cels.2016.08.011. PMID: 27667365
10/26/2016	Surprising Heterogeneity of Pancreatic Islet Cell Subsets Blodgett DM, Redick SD, Harlan DM. Cell Syst 2016 Oct 26;3(4):330-332. doi: 10.1016/j.cels.2016.10.009. PMID: 27788358
10/26/2016	Rebranding asymptomatic type 1 diabetes: the case for autoimmune beta cell disorder as a pathological and diagnostic entity Bonifacio E, Mathieu C, Nepom GT, Ziegler AG, Anhalt H, Haller MJ, Harrison LC, Hebrok M, Kushner JA, Norris JM, Peakman M, Powers AC, Todd JA, Atkinson MA. Diabetologia2016 Oct 26. [Epub ahead of print] PMID: 27785529
10/26/2016	Surprising Heterogeneity of Pancreatic Islet Cell Subsets Blodgett DM, Redick SD, Harlan DM. Cell Syst 2016 Oct 26;3(4):330-332. doi: 10.1016/j.cels.2016.10.009. PMID: 27788358
10/24/2016	Vascular development in the vertebrate pancreas Azizoglu DB, Chong DC, Villasenor A, Magenheim J, Barry DM, Lee S, Marty-Santos L, Fu S, Dor Y, Cleaver O. Dev Biol. 2016 Oct 24. pii: S0012-1606(16)30428-6. doi: 10.1016/j.ydbio.2016.10.009. PMID: 27789228
08/01/2016	Genome therapy of myotonic dystrophy type 1 iPS cells for development of autologous stem cell therapy Gao Y, Guo X, Santostefano KE, Wang Y. Reid T, Zeng D, Terada N, Ashizawa T, Xia G. Mol. Ther. 24:1378-87, Aug, 2016 PMID: 27203440
08/01/2016	DNA Damage and Aging Around the Clock Gutierrez-Martinez P, Rossi DJ, Beerman I. Trends Mol Med. 2016 Aug;22(8):635-7. doi: 10.1016/j.molmed.2016.06.006. Epub 2016 Jun 23. PMID: 27345866
07/09/2016	Mutant IDH1 Downregulates and Alters DNA Repair and Sensitivity to DNA Damage Independent of TET2 Inoue S, Li WY, Tseng A, Beerman I, Elia AJ, Bendall SC, Lemonnier F, Kron KJ, Cescon DW, Hao Z, Lind EF, Takayama N, Planello AC, Shen SY, Shih AH, Larsen DM, Li Q, Snow BE, Wakeham A, Haight J, Gorrini C, Bassi C, Thu KL, Murakami K, Elford AR, Ueda T, Straley K, Yen KE, Melino G, Cimmino L, Aifantis I, Levine RL, De Carvalho DD, Lupien M, Rossi DJ, Nolan GP, Cairns RA, Mak TW. Cancer Cell. 2016 Jul 9. [Epub ahead of print] PMID: 27424808. [PMCID in process].
06/06/2016	Non-genotoxic conditioning for hematopoietic stem cell transplantation using a hematopoietic-cell-specific internalizing immunotoxin. Palchaudhuri R, Saez B, Hoggatt J, Schajnovitz A, Sykes DB, Tate TA, Czechowicz A, Kfoury Y, Ruchika F, Rossi DJ, Verdine GL, Mansour MK, Scadden DT. Nature Biotechnology. 2016 Jun 6. [Epub ahead of print] PMID: 27272386.
04/01/2016	Developing Drosopila to discover the hormonal orgins of type 2 diabetes mellitus R. Alfa, S. Kim Dis Model Mech. 2016 Apr 1;9(4):365-76. doi: 10.1242/dmm.023887
03/29/2016	Mitotic history reveals distinct stem cell populations and their contributions to hematopoiesis Säwén P, Lang S, Mandal P, Rossi DJ, Soneji S, Bryder D. Cell Reports. Epub 2017 Mar 17. doi:10.1016/j.celrep.2016.02.073
12/15/2015	Molecular Interactions Governing Autoantigen Presentation in Type 1 Diabetes Nakayama M, Simmons KM, Michels AW. Curr Diab Rep. 2015 Dec;15(12):113. doi: 10.1007/s11892-015-0689-z. Review. PMID: 26458384
12/01/2015	Vascular smooth muscle cells from hypertensive patient-derived induced pluripotent stem cells to advance hypertension pharmacogenomics Biel NM, Santostefano KE, DiVita BB, El Rouby N, Carrasquillas S, Simmons C, Nakanishi M, Cooper-DeHoff RM, Johnson JA, Terada N Stem Cells Transl. Med. 4:1380-90, Dec, 2015 PMCID: 4675511
11/20/2015	Humanized Mouse Models for Transplant Immunology Kenney LL, Shultz LD, Greiner DL, Brehm MA. Am J Transplant. 2016 Feb;16(2):389-97. doi: 10.1111/ajt.13520. Epub 2015 Nov 20. PMID: 26588186
10/01/2015	Directed differentiation of embryonic stem cells into cardiomyocytes by bacterial injection of defined transcriptional factors Bai F, Lim CH, Jia J, Santostefano KE, Simmons C, Kasahara H, Terada N, Jin S Sci. Rep. 5:15014, Oct, 2015 PMCID: 4511150
08/01/2015	Efficient gene editing in pluripotent stem cells by bacterial injection of TALEN proteins Jia J, Bai F, Santostefano KE, Wu D, Wu W, Terada N, Jin S Stem Cells Transl. Med. 4:913-26, Aug, 2015 PMCID:4598736
06/10/2014	Differential cell autonomous responses determine the outcome of coxsackievirus infections in murine pancreatic α and β cells Marroqui L, Lopes M, dos Santos R, Grieco F, Roivainen M, Richardson SJ, Morgan NG, de beeck AO, Eizirik D. ELife. 2015 Jun 10;4:e06990. doi: 10.7554/eLife.06990.

Publications of Interest

Follow