Human Islet Research Network


HIRN was established in 2014 to help organize and support collaborative research related to the loss of functional beta cell mass in Type 1 Diabetes (T1D). The project consists of five independent research initiatives:

  • Human Pancreas Analysis Program (HPAP)

    • HPAP is performing deep phenotyping of the human endocrine pancreas and its interaction wit the immune system to better understand the cellular and molecular events that precede and lead to beta cell loss in T1D.

The project is managed with an Administrative Hub consisting of Program Staff at the NIH NIDDK, a Coordinating Center (CC) and a Bioinformatics Center (BC).The project is supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the Type 1 Diabetes special funding program.