Job Postings – Research
The Lilly Diabetes Center of Excellence (LDCE) at the Indiana Biosciences Research Institute (IBRI) is recruiting promising young investigators to start their own independent laboratories under excellent research conditions. The LDCE is recruiting high-potential Principal Investigators (PIs) at the IBRI in Indianapolis, Ind., who are interested in pancreatic beta cell research, particularly related to iPSC-derived beta cells and the crosstalk between beta cells and the immune system in type 1 diabetes (T1D). You may obtain additional information by contacting Dr. Decio Eizirik.
Date Posted: November 6, 2019 Job Announcement (129 downloads)
The Diabetes Center of Excellence at the University of Massachusetts Medical School invites applications for a SENIOR TENURED or JUNIOR TENURE-TRACK basic science or clinical investigator faculty position. The Diabetes Center of Excellence currently consists of basic and physician scientists representing a broad range of disciplines in the biomedical and clinical sciences, with members from several Medical School Departments and Programs working together as central New England’s leading center for diabetes clinical care, innovation, and discovery. The Center occupies state-of-the-art research space on an expanding Medical School campus. Basic investigators benefit from core facilities for deep sequencing, proteomics, genotyping, fluorescence-activated cell sorting, digital imaging/confocal microscopy, genomics/bioinformatics, transgenic/knockout mice, and mouse metabolic phenotyping. Clinical and community investigators benefit from infrastructure for recruitment and retention of research participants, measurement, behavioral and nutritional intervention resources and facilities, and academic-community research partnerships. Adult and pediatric clinical efforts of the Diabetes Center are housed in a wonderful Ambulatory Clinical Care building designed so that patients can receive appropriate retinal photos, foot care, diabetes education, and other routine medical care at one location. The position will be highly competitive with regard to start-up funds, laboratory space (if needed) and salary. The Center seeks an individual of outstanding research potential relating to diabetes pathophysiology or treatment. Applicants should send curriculum vitae, statement of research interests, and names and addresses of three references to Drs. Harlan and Greiner c/o Patricia Cannon.
Date Posted: August 27, 2019 Job Announcement (172 downloads)
The Diabetes Clinical Research Program (DCRP) at Benaroya Research Institute seeks to recruit outstanding applicants for a new faculty position. The appointment will be at the at the assistant, associate or full member level, commensurate with experience, training and achievement. The DCRP is an international leader in type 1 (autoimmune) diabetes research. The program’s goal is to help families with type 1 diabetes by investigating ways to prevent the disease, finding new approaches of diagnosing it in its earliest stage to optimize the potential for successful treatment, and testing innovative new therapies. Benaroya Research Institute seeks to recruit outstanding applicants for a new faculty position. The appointment will be at the at the assistant, associate or full member level, commensurate with experience, training and achievement. The DCRP is an international leader in type 1 (autoimmune) diabetes research. The program’s goal is to help families with type 1 diabetes by investigating ways to prevent the disease, finding new approaches of diagnosing it in its earliest stage to optimize the potential for successful treatment, and testing innovative new therapies. Qualified candidates should send inquiries or an application package comprising their curriculum vitae, a letter explaining their motivation, research interests and qualifications to Diabetes Recruit.
Date Posted: July 5, 2019 Job Announcement (148 downloads)
The University of Miami Miller School of Medicine Department of of Microbiology and Immunology is accepting applications for Assistant and Associate Professor level for investigators with research interests related to immunotherapy of cancer, autoimmunity, or infectious diseases. We are particularly interested in applicants that study the human immune response and have an established funded research program. Significant resources will be made available toward this recruitment. Applicants should have a Ph.D., M.D. or equivalent, at least 3 years of postdoctoral training, and a willingness to contribute to the missions of the Department of Microbiology and lmmunology and the Miller School of Medicine. Quality research facilities, start-up funds, and salary support will be provided to the appointees. Applicants should send a curriculum vitae, statement describing research accomplishments and future research goals, relevant reprints, and the names of three references to Ms. Silvia Arguelles.
Date Posted: December 12, 2018 Job Announcement (282 downloads)
Research Scientist Position
The University of Washington Diabetes Research Center (DRC) Cell Function Analysis Core is recruiting a Research Scientist working to work on isolation of islets and other cell types using microsurgical and gradient purification techniques and cell culture; and investigating the function, bioenergetics and intracellular signaling in cells/islets from normal and diabetic models/patients using a variety of assays including sophisticated, real-time spectroscopic and imaging techniques. In addition, effort will be spent on the development of instrumentation for cell analysis that involves the design, implementation, testing and optimization of optical sensors and microfluidics. Opportunities will be available for writing and publishing manuscripts both on mechanisms mediating and regulating insulin secretion, as well as new optical and fluidic technologies. Please send a brief cover letter and resume (containing 2-3 references) to Dr. Ian Sweet.
Date Posted: June 30, 2020 Job Announcement (27 downloads)
Postdoctoral Fellow Positions
The University of Chicago beta cell/diabetes research group under the direction of Dr. Raghu Mirmira has funded openings for several postdoctoral research scientists with interest in applying/learning cell biological techniques (immunoprecipitation, immunohistochemistry, confocal imaging), mouse genetic skills, human islet biology, and immunology and inflammation research. NIH-funded research projects in the Mirmira laboratory include the study of beta cell development and function, human islet gene regulation and mRNA translation, and islet cytokine signaling in the context of type 1 diabetes. The University of Chicago Diabetes Center is a highly interactive and diverse research environment with a strong history of mentoring and career development of junior scientists. In addition to a rich research environment, the Center and School of Medicine provide numerous scientific seminar series, career development workshops, and the opportunity to interact with a diverse pool of international scientists in a dynamic and exciting city. Interested applicants are encouraged to send an updated CV and names of 3 references to Dr. Raghu Mirmira, MD, PhD, Director, Department of Medicine, University of Chicago
Date Posted July 31, 2020
Two postdoctoral fellow positions at the Indiana Biosciences Research Institute are available in the IBRI Diabetes Center. We are looking for highly motivated researchers to join the IBRI in the lab of Dr. Decio Eizirik. This lab aims to clarify the mechanisms of pancreatic beta cell dysfunction and death in type 1 diabetes mellitus, with focus on endoplasmic reticulum stress, alternative splicing and other mechanisms that may contribute to beta cell death and generation of neoantigens.The selected candidate will participate in a team working with primary human and rodent islets, animal models of diabetes and human beta cell lines, and advanced molecular biology techniques. A strong understanding of beta cell biology and/or molecular biology is important. The selected candidate will be motivated and take initiative in proposing and performing experiments, with support by Dr. Eizirik and other colleagues in the lab. Applications can be made here. You may also contact Dr. Decio Eizirik directly for additional information.
Date Posted: February 19, 2020 Job Announcement (67 downloads)
Postdoctoral positions in the Kulkarni Lab at Joslin Diabetes Center, Harvard Medical School. Applications are invited for prospective Post-Doctoral Fellows to train in the Kulkarni Lab. The position is available immediately for a period of 2 years with the possibility of extending for a third year based on available funds and performance of the Fellow. Applications are invited from qualified individuals with a PhD or MD or MD PhD degrees and interested in working in exciting projects focused on defining pathways and identifying mechanisms that regulate pancreatic (endocrine and exocrine) biology and interrogating inter-organ cross talk in the overall maintenance of glucose homeostasis. Successful candidates should have a strong background in molecular biology, cell biology and biochemistry. It is strongly preferable to have prior experience in bioinformatics and the ability to interrogate “omics” and sequencing datasets. Prospective candidates should possess skills in handling human islets and undertake animal studies. It would be an advantage to be able to undertake rodent islet isolation, and perform immunostaining. Applicants should provide a brief statement of research interests, CV, and the names of three references to Angellica Meng
Date Posted: June 12, 2020
The Department of Pathology at the Children’s Hospital of Philadelphia is seeking a highly motivated individual for a postdoctoral position. Our laboratory focuses on using human embryonic stem cell and iPS cell models to study human pancreatic development and diabetes. The NIH funded position aims to use the human ES/iPS system to study monogenic forms of diabetes using genome engineered stem cell lines. Applicants must have a PhD or MD degree in the biological or physical sciences. Prior laboratory experience in cell culture, basic molecular biology, and flow cytometry is preferred. The position is available Fall of 2020, with some flexibility for a later start date. CV, letters of reference and cover letter can be emailed to Dr. Paul Gadue.
Date Posted: June 12, 2020 Job Announcement (31 downloads)
The Department of Microbiology and Immunology at the University of Miami, Miller School of Medicine, has an exciting opportunity for a Postdoctoral Associate. We are seeking a highly motivated, ambitious, creative, and dynamic postdoctoral research fellow to join Dr. Serafini’s, NIH-funded, translational group for projects in immunology, targets discovery, and in vivo targeted delivery of therapeutics and imaging reagents. Our group is pioneering the use of RNA therapeutics for the in vivo genetic modulation of beta cells and tumor infiltrating myeloid cells. This allows an unprecedented opportunity not only to understand the beta cell biology in diabetes and myelopoiesis in cancer, but also for the development of new therapeutics for clinical use. The main project that the Postdoctoral Associate will be involved in is delivery of therapeutics to human beta cells using newly discovered RNA aptamers specific for human and mouse beta cells. Thus, the candidate must possess skills in molecular biology, sh-, sa-, and guide- RNA and proven experience in manipulating pancreatic islets and work with animal models. Ph.D. or other doctoral degree in molecular biology, endocrinology, immunology, or similar fields or M.D. Prefer proven experience in molecular biology and RNA. Good knowledge of aptamer technology and beta cell biology. Ability to successfully handle samples and perform immunology techniques and cell culture in a BSL2 setting. Must have a strong record of productivity and publication in the field of pancreatic islets and/or diabetes. Apply here.
Date Posted: May 18, 2020
One Laboratory Assistant position at the Indiana Biosciences Research Institute is available in the IBRI Diabetes Center. We are looking for highly motivated laboratory assistant to join the IBRI in the iPSC Core Facility coordinated by Dr. Decio Eizirik. This Core aims to differentiate pancreatic beta cells and other cell types departing from iPSC cells.The selected candidate will participate in a team working with iPSC derived beta cells, functional studies and advanced molecular biology techniques. The selected candidate will be motivated and take initiative in proposing and performing experiments, with support by Dr Eizirik and other colleagues in the iPSC Core. Applications can be made here. You may also contact Dr. Decio Eizirik.
Date Posted: February 19, 2020 Job Announcement (56 downloads)
The laboratory of Dr. Seung Kim at the Stanford University School of Medicine and the Stanford Diabetes Research Center has an immediate opening for a post-doctoral fellow to work on one or more projects involving organ regeneration and development, stem cells, and diseases like diabetes mellitus. Our group has pioneered unique experimental approaches and integrative studies with primary human tissues, pigs, mice and fruit flies. We use classical methods and an array of modern assays including single cell and bulk RNA-Seq and ATAC-Seq, CLARITY, and CODEX. We are looking for self-motivated individuals willing to learn from a cheerful PI and our friendly team in the stimulating environments of the Stanford Department of Developmental Biology, the Stanford Diabetes Research Center and the JDRF Northern California Center of Excellence. Applicants with skills or interest in developmental biology, cell and stem cell biology, immunology, genetics, physiology and/or bioinformatics are especially encouraged to apply. Previous experience working with mice, mammalian cell culture, statistical and computational methods for analyzing genome-scale data sets or large imaging files is an asset, but not required. Prior experience with pancreas or islet biology, or diabetes research is not necessary. For those with a background in fruit fly genetics and an interest in developing a teaching-based career, there are special training opportunities with us. If interested, please send a cover letter, detailed CV, and names of three references directly to Ms. Ngan Tefera.
Date Posted: February 4, 2020
The Department of Molecular & Medical Genetics at Oregon Health & Science University (OHSU) in Portland, Oregon, is seeking a highly motivated and enthusiastic post-doctoral fellow to study adeno-associated virus (AAV) and its application for human gene therapy in the lab led by Professor Hiroyuki Nakai, M.D., Ph.D. Specifically, the lab is looking for a post-doctoral researcher who can lead productively a newly funded multi-PI (MPI) NIH project ” U01DK123608 (MPIs: Nakai, Grompe and Kay): Gene Therapy for Diabetes, ” where we seek to develop clinically relevant novel AAV vectors and methods for in vivo regeneration of insulin-secreting beta cells in rhesus macaques and profoundly understand the mechanisms behind the technologies. The main research focuses of the Nakai lab are: (1) AAV vector biology – capsid assembly, genome packaging, and virus-host interactions in rodents and non-human primates; (2) AAV antigen-antibody interactions; (3) developing novel vectors by engineering of AAV capsids; and (4) preclinical studies of gene therapy for the treatment of various human diseases including type I diabetes. The lab takes a multidisciplinary approach to solving these problems, utilizing both wet and dry lab techniques. The lab is a part of the Human Islet Research Network (HIRN) supported by the NIH NIDDK. The successful candidate will join a multidisciplinary collaborative team and participate in global collaboration in the HIRN community, with an ultimate goal to develop AAV gene therapy for type I diabetes. The successful candidate will also contribute to the training of graduate, undergraduate, and high school students, as well as research staff. Please send a cover letter and C.V. to Hiroyuki Nakai, M.D., Ph.D.
Date Posted: January 22, 2020 Job Announcement (61 downloads)
The Department of Pathology, Immunology and Laboratory Medicine, University of Florida Diabetes Institute is seeking creative and highly motivated individuals for the position of Postdoctoral Associate under the direction of Dr. Todd Brusko. The Postdoc will be engaged in studying novel pathways regulating the differentiation and pathogenicity of T cells, the function of regulatory T cell biology in autoimmunity. Work includes use of animal models and human samples. Immunology, in vivo mouse models, and flow cytometry experience are preferred. The successful candidate will be expected to design and implement projects, work with both human samples and mice, collaborate within and between labs, participate in the drafting of scientific publications and funding proposals, and may, with direction from the PI, supervise technical support personnel. The selected individual will receive strong mentoring to promote scientific growth and development. Candidates should submit a curriculum vitae, NIH Biosketch/personal research statement (one-two pages), and three letters of recommendation. The letters of reference should be sent directly to Prof. Todd Brusko.
Date Posted: December 3, 2019
We are looking for recent Ph.D to pursue a career in science and biotechnology at the intersection of immunology and aging. People trained in my lab pursue careers in academia, biotech start-ups, venture funds or consultants for large firms. The long-term goal of my research is to understand the role of tissue secretory senescent cells in diseases such as autoimmunity, diabetes and diseases of aging. We have identified key immune cells that can selectively eliminated senescent cells in a number of diseases associated with aging. We use a combination of mouse models of autoimmunity and humanized mouse models transplanted with senescent cells to investigate the underlying mechanism by which tissue senescent cells contribute to the development of the various diseases. We pay salaries that are more generous than traditional academic scales. The collegiality and interdepartmental organization at UCSF fosters interdisciplinary research that helps hone research skills, critical thinking, and scientific writing for a broad range of jobs. Please send cover letter and CV/resume to Dr. Anil Bhushan.
Date Posted: October 25, 2019
Postdoctoral position at Rutgers University/Robert Wood Johnson Medical School in the Lab of Dr. Abdelfattah El Ouaamari. Recruiting for a self-driven, creative and organized candidates with a PhD in neuroscience, biochemistry or molecular and cellular biology are encouraged to apply. The candidate must possess skills in manipulating and assessing neuronal activity. Prior experience working with rodents is required. Preference will be given to applicants who also have experience with pancreatic islets. Candidates should have a strong record of productivity and publication in the fields of neuroscience/neurobiology or islet biology. Interested individuals should send CV, cover letter and names and details of 3 references directly to Dr. El Ouaamari.
Date Posted: April 11, 2019 Job Announcement (232 downloads)
Postdoctoral position in the Lab of Dr. Sangeeta Dhawan at the Beckman Research Institute at City of Hope, in Los Angeles county, CA to study the epigenetic regulation of pancreatic beta cell mass. The candidate should have a PhD in molecular, cell, or developmental biology. Experience in genetic mouse models, islet biology, physiology, molecular biology, high throughput sequencing is desirable. The candidate should send a cover letter/statement of research interests, CV, and contact information for three references directly to Dr. Sangeeta Dhawan
Date Posted: February 8, 2019
Postdoctoral position in the Lab of Dr. Doris Stoffers in the Institute for Diabetes, Obesity, and Metabolism within the Perelman School of Medicine at the University of Pennsylvania. We are investigating molecular mechanisms whereby pancreatic beta cells respond to stress. Failure of beta cell numbers or function underlies the progression of all forms of diabetes and we envision that our progress in this area could identify new nodes to target for therapeutic intervention. Our current efforts are focused on a stress responsive Pdx1 containing transcriptional complex and its targets and on the role of the polyC binding protein family of RNA binding proteins in the post-transcriptional regulatory landscape of beta cells. A PhD is required; experience in genetic mouse models, islet physiology, advanced molecular techniques, high throughput sequencing methodologies and bioinformatics, proteomics, metabolomics is helpful. Please send a brief statement of research interests, CV and contact information for three references to Dr. Doris Stoffers
Date Posted: November 11, 2018
Postdoctoral position at University of Pennsylvania to be part of the Human Pancreas Analysis Program (HPAP). The individual will contribute to our project on “Drivers and consequences of beta cell DNA damage in type 1 diabetes” within HIRN CBDS consortium. We propose to develop novel technologies to determine physiological responses to genomic stress in human beta cells, including the potential accumulation of somatic mutations, all at the single cell level. We will analyze the cumulative mutation load of human beta-cells in diabetes, based on our hypothesis that metabolic insults and abortive replication attempts result in the accumulation of somatic mutations, contributing to loss of function and possibly to immunogenicity in diabetes. To accomplish this goal, we will determine the cumulative mutation load of stressed beta-cells using single cell exome-, RNA-, and ATACseq analysis. We will employ cutting-edge and emerging technologies that are already established in our laboratories. We have assembled an outstanding team of scientists with complementary expertise, ranging from human islet transplantation to computational biology, to assemble an atlas of the human endocrine pancreas in health and disease at the single cell level. The successful applicant will join a highly interactive and productive team, and will build on our existing technologies existing in the Kaestner Lab. Ph.D. or equivalent are required, with expertise islet biology and molecular genetics. Send CV and two letters of recommendation directly to Dr. Klaus Kaestner.
Date Posted: August 21, 2018
Stanford University is seeking a Life Science Research Professional 1 to perform basic functions and activities involved in defined research projects, and independently conduct and analyze experiments as part of the Translational Genomics of Diabetes. (TGD) laboratory. The Translational Genomics of Diabetes Laboratory headed by Dr Anna Gloyn is affiliated with the Division of Endocrinology in the department of Pediatrics. The overall research focus of the lab is to use human genetics to understand pancreatic islet dysfunction in type 2 diabetes and related disorders. Current projects involve integrating diverse genetic, epigenomic and cellular datasets to identify causal variants and effector transcripts at GWAS loci for type 2 diabetes and related disorders. The TGD Laboratory is physically located at Porter Drive with research groups from the Department of Genetics. Applications can be made here and for more information contact Dr. Anna Gloyn.
Date Posted: July 2, 2020
Stanford University is seeking a Computational Biologist/ Biostatistician 1 to join the Translational Genomics of Diabetes (TGD) Lab which is headed by Dr Anna Gloyn. The overall research focus of the lab is to use human genetics to understand pancreatic islet dysfunction in type 2 diabetes and related disorders. Current projects involve integrating diverse genetic, epigenomic and cellular datasets to identify causal variants and effector transcripts at GWAS loci for type 2 diabetes and related disorders. The TGD Laboratory headed by Dr Anna Gloyn is affiliated with the Division of Endocrinology in the Department of Pediatrics although the group are physically located at Porter Drive with research groups from the Department of Genetics including Mike Cherry and Mike Synder. Applications can be made here and for more information contact Dr. Anna Gloyn.
Date Posted: July 2, 2020
The laboratory of Dr. Vincent Poitout is seeking a PhD student interested in cell biology, signalling and glucose homeostasis. Requirements: MSc. degree in biochemistry, cell biology or physiology (or equivalent) and be eligible to the biochemistry, pharmacology or physiology programs at the Université de Montréal. Our laboratory is focusing on pancreatic beta-cell biology and its perturbations in type 2 diabetes (www.poitoutlab.ca). The objective of this project is to explore the mechanisms whereby the pancreatic beta-cell increases its functional mass during puberty and their impact on glucose homeostasis in adulthood, using a combination of in vitro and in vivo approaches. The candidate will receive a scholarship according to the CIHR guidelines. Application to training awards from funding agencies is strongly encouraged. Interested students should send a motivation letter, a complete CV, university transcripts and 2-3 names of potential references to Dr. Vincent Poitout, before July 31, 2020.
Date Posted: July 2, 2020 Job Announcement (16 downloads)