The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope

A Research Associate II opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes.  Major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials.  Interested Applicants for the position should send a CV, a brief statement of their research interests, and contact information for three references to Dr. Alberto Pugliese.

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The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope

A Postdoctoral Fellowship opportunity is immediately available for the highly motivated individual in the laboratory of Dr. Alberto Pugliese, MD in the AR-DMRI Department of Diabetes Immunology. The research is highly translational and primarily focused on human type 1 diabetes. The candidate will participate in several projects. Major ongoing projects are investigating miRNA biomarkers, pancreas pathology, and novel therapeutics, also in the context of the analysis of live pancreas tissue from organ donors obtained from the Network for Organ Donors with Diabetes (nPOD), of which Dr. Pugliese is Executive Co-Director, and in future clinical trials. Upcoming studies are projected to include the analysis of samples from patients with type 1 diabetes participating in clinical trials, with trials expected to start in late 2023 and 2024. Additional studies involve analysis of samples from recipients of pancreas-kidney transplant in the context of recurrent type 1 diabetes.  Interested Applicants for the position should send a CV, a brief statement of their research interests, and contact information for three references to Dr. Alberto Pugliese.

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The Arthur Riggs Diabetes & Metabolism Research Institute at City of Hope

The Department of Diabetes Immunology within the Arthur Riggs Diabetes & Metabolism Research Institute (AR-DMRI) at City of Hope has an opening at any professorial rank (Assistant/Associate or full professor). The successful candidate will be a scientist with interest in understanding islet autoimmunity and more broadly the disease pathogenesis at the preclinical and/or clinical levels and with the desire to translate promising insights into biomarkers, treatments and potential cures for type 1 diabetes. Interested Applicants for the position should send a CV, a brief statement of their research interests, and contact information for three references to Dr. Alberto Pugliese.

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University of Alabama at Birmingham

A Postdoctoral Fellowship position is available in the Department of Cell, Developmental and Integrative Biology (CDIB) at the University of Alabama at Birmingham (UAB).The position is available for a minimum period of two years. A major requirement will be expertise in molecular biology approaches and experience with CRISPR technology. The applicant will also be expected to have working knowledge of animal work (genotyping, islet and immune cells isolation); in vivo analyses (glucose tolerance and insulin sensitivity); in vitro assays with beta-cells and immune cells; Western blotting; immunofluorescence analyses; and proficiency with RT-qPCR protocols.  Please send curriculum vitae and names of three references to: Dr. Sasanka Ramanadham.

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University of California, San Francisco

The Parent lab at the UCSF Diabetes Center is seeking applicants for a full-time Specialist position at the Junior or Assistant level. Our research is focused on understanding changes in immune tolerance that lead to autoimmune destruction of pancreatic insulin-producing beta cells in type 1 diabetes (T1D). We are combining directed differentiation of human pluripotent stem cells into cell types relevant to T1D with genome engineering approaches to model the human disease. We are also developing strategies to produce immune evasive stem cell-derived pancreatic beta cells to accelerate clinical translation of cell therapies to treat diabetes.  Specialist appointed at the Junior level must possess (or in process of obtaining) a BA/BS degree in biological or biochemical sciences (or a related field); Specialist appointed at the Assistant level must possess (or in process of obtaining) a MA/MS degree in biological or biochemical sciences (or a related field).  For more information please contact Dr. Audrey Parent.

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ULB Center for Diabetes Research

The ULB Center for Diabetes Research, Brussels, Belgium is looking for a highly motivated postdoctoral fellow to join the lab of Dr. Decio Eizirik. This lab aims to clarify the mechanisms of pancreatic beta cell dysfunction and death in type 1 diabetes mellitus, with focus on endoplasmic reticulum stress, alternative splicing and other mechanisms that may contribute to beta cell death and generation of neoantigens. Interested individuals are encouraged to provide a brief letter stating their accomplishments and interest in the lab’s research, curriculum vitae, and a list of three references to Dr. Decio Eizirik.

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Indiana University Purdue University Indianapolis

The Department of Biology at Indiana University Purdue University Indianapolis (IUPUI) invites applications for a tenure-track faculty position at the rank of Assistant Professor. Competitive salary and start-up funds are available. A Ph.D. and postdoctoral experience are required. Applicants must demonstrate the ability to initiate a research program that can attract external funding to sustain it, dedication to effective student mentoring and the ability to teach courses at the graduate and undergraduate levels. Candidates able to teach courses in microbiology, biochemistry and neuroscience are particularly welcome. Research strengths in the department span a range of topics in cellular, molecular, and organismal biology.  Applicants for the position should provide a brief statement of research interests, CV and the names of three references to Dr. Mastracci

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Eli Lilly and Company

The Islet Cell Therapy and Stem Cell Biology group at Lilly Research Laboratories, is looking for an in vitro biologist with training in human iPSC culture. This position will play a key role in establishing a new lab focused on developing the next generation of islet cell therapies and application of iPSC-derived platforms to novel target discovery and validation. Qualified individuals will have experience with human iPSC culture, gene editing, molecular biology and assay development, as well as broad experience in pancreas and islet biology.  Applicants for the position should provide a brief statement of research interests, CV and the names of three references to Dr. Gopika Nair.

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Medical College of Wisconsin

The laboratory of Dr. Xuelin Lou at the Medical College of Wisconsin is seeking a highly motivated and creative Postdoctoral Fellow to lead exciting research projects on membrane trafficking in islet β cells. We are dedicated to understanding the molecular mechanisms that regulate β cell exocytosis, endocytosis, and autophagy in physiological and diabetic conditions. We utilize primary islet cell cultures, viral transduction, live-cell imaging, patch-clamps, super resolution microscopy (SIM/PALM/STORM/STED/ExM), EM-tomography, multi-omics, and mouse models to achieve our research goals . The ideal candidate will have a Ph.D. in Biology (or a related field) and quality publications. Experience in islet biology, or expertise in relevant research methods is highly desirable. Please send your cover letter, curriculum vitae, and the name/contact of three references to Dr. Xuelin Lou

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Mayo Clinic Arizona

The Khosravi Immunoengineering Lab in the Department of Immunology at the Mayo Clinic Arizona is seeking two Postdoc Research Fellows in the areas of autoimmunity and transplantation. The Immunoengineering Lab research focuses on developing and applying novel ways of inducing immune tolerance using integrated approaches that combine laboratory, clinical, and computational methods. The engineering of immune cells is an integral part of these novel methods. The focuses of current research projects: 1) to develop chimeric antigen receptor (CAR) Tregs with enhanced stability and functionality for inducing immune tolerance in transplantation and xenotransplantation; 2) to study Tregs in autoimmune diseases and apply engineering strategies to develop autologous Treg therapies for these patients. In both studies, in vitro assays and humanized mouse models will be used to test the effectiveness of Treg-based immunotherapies.  Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to Dr. Mohsen Khosravi Maharlooei.

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University of California San Diego

The Laboratory of Dr. Vira Kravetz at the University of California San Diego,  Department of Bioengineering and Department of Pediatrics , is looking for a creative and highly motivated Postdoctoral Fellow to lead experimental and computational research projects. The successful candidate will have a PhD in Bioengineering, Biology, Biophysics, Mathematics, or related fields. Desired (but not required) skills:  experience in animal work (mouse or zebrafish) and tissue culture, willingness to perform animal surgical procedures, MATLAB, C (or other languages), signal analysis.  Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to Dr. Vira Kravets.

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University of Pennsylvania Perelman School of Medicine

The Alvarez laboratory at the University of Pennsylvania Perelman School of Medicine seeks a creative, collaborative and highly independent postdoctoral fellow to lead new research projects. Our laboratory asks how circadian & metabolic rhythms impact islet cell maturity, aiming to build mature stem cell-derived organoids as human models of islet development & physiology and as diabetes cell therapy. We are unraveling genetic, chromatin, and translation circuits that govern islet maturity states in health and disease. Candidates must have quality first-author publications and a PhD in Biology, Bioengineering, or related fields. Computational/bioinformatics expertise is highly desirable. We embrace diversity, equity, and inclusion. Please send your CV, a brief statement of relevant research interests, and contact information for three references to Dr. Juan Alvarez

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University of Montreal

The laboratory of Dr. Vincent Poitout, at the The University of Montreal has a postdoctoral position available to decipher the mechanisms whereby very long-chain sphingolipids lead to reactive oxygen species production and cell-cycle activation in rodent and human beta-cells. Methodologies to be employed include rat and mouse islet isolations, adenoviral transduction of rodent and human islets, measurements of beta-cell proliferation by flow cytometry, assessment of hormone secretion in static incubations and perifusions, and islet transplantation studies. Interested applicants please send a cover letter and curriculum vitae, including the names of three references, to Dr. Vincent Poitout

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University of Colorado CU Anschutz Medical Campus

The Barbara Davis Center for Diabetes (BDC) at the University of Colorado Anschutz Medical Campus is searching for an Assistant or Associate Professor. The person holding this position will develop and direct an independent, externally funded research program related to the development and/or investigation of the molecular and/or cellular mechanisms operative in human stem cell models related to understanding the etiology of Type 1 Diabetes or developing human stem cell derived therapies.  This individual will be responsible for the daily management, supervision, training and evaluation of personnel (such as graduate students, postdoctoral fellows and professional research assistants) whose positions are funded by research grants on which s/he is the principal investigator.  For more information and official job posting, please contact Dr. Lori Sussel.

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Joslin Diabetes Center, Harvard Medical School

A iPS Core Manager position in available at the Kulkarni Lab at Joslin Diabetes Center, Harvard Medical Center.  The Core Manager will set up the infrastructure, equipment and supervision of the functionality of generating human iPS cells from patient samples in the long-term goal of generating insulin-secreting beta-like cells for testing in ex vivo and in vitro studies.  This role will primarily be responsible for supervising the laboratory as well as having the expertise to undertake hands-on work if necessary, to insure timely progress of the projects.  Applicants for the position should provide a brief statement of research interests, CV and the names of three references to Dr. Kulkarni.

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University of California, San Francisco

The laboratory of Dr. Audrey Parent at the University of California, San Francisco is seeking postdoctoral fellows interested in developing immune evasion strategies for beta cell replacement therapy. Our research program is diverse, combining directed differentiation of human pluripotent stem cells into pancreatic beta cells and thymic epithelial cells with genome engineering approaches to study autoimmunity in humanized models. Selected candidates will work in a collaborative and interdisciplinary team and will be encouraged to develop their own research interests. Candidates must have a PhD in biology, immunology, or a related field. Applicants for the position should send a CV, a brief statement of their research interests, and contact information for three references to Dr. Audrey Parent

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NIDDK Division of Diabetes, Endocrinology & Metabolic Diseases

Tissue Crosstalk in Metabolic Disease

Program Director

The Director of Tissue Crosstalk in Metabolic Disease programs in the Division of Diabetes, Endocrinology and Metabolic Diseases of NIDDK (DDEMD) will work closely with the Division Director to enhance research activity by identifying opportunities for enabling basic research investigating the role of Tissue Crosstalk in diseases of interest to DDEMD.   Tissue crosstalk grant portfolios and programs will encompass research focused on the development and regulation of metabolic diseases (including diabetes and obesity) at the molecular, cellular and tissue level.  Organs and systems relevant to metabolic disease generally include adipose tissue, liver, pancreas, and muscle. In addition, other systems such as the peripheral and central nervous systems, the immune system, vascular and lymphatic tissue may also play key roles in tissue function and metabolic disease, thereby requiring a systems biology or systems medicine approach. 

     The Program Director for Tissue Crosstalk in Metabolic Disease should be familiar with the state of the science in this area, and possess the expertise in cellular biology, endocrinology, physiology, and/or molecular biology needed to assess research needs and advance the field. It is expected that this research portfolio will be focused on basic mechanisms, emerging technologies, new models, and current concepts in systems biology as they are applied to multi-organ communication processes influencing metabolic disease.  The Program Director will be expected to identify emerging opportunities, develop initiatives based on scientific priorities, advise potential applicants, and administer grants and awards. The applicant must have a professional scientific degree (Ph.D. or M.D.), scientific management experience, and strong interpersonal and written communication skills.

Please prepare to apply to the upcoming job announcement for GS-12/13/14 HSA (Program Officer/Scientific Review Officer) through USAjobs.gov

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NIDDK Division of Diabetes, Endocrinology & Metabolic Diseases

Neural Mechanisms of Metabolic Control

Program Director

The Director of the Neural Mechanisms of Metabolic Control program in the Division of Diabetes, Endocrinology and Metabolic Diseases of NIDDK (DDEMD) will work closely with the Division Director to enhance research activity by identifying opportunities for enabling basic and translational research investigating the role of the peripheral nervous system in the regulation of metabolic function and metabolic diseases of interest to DDEMD, specifically obesity and diabetes. The autonomic nervous system, composed of sympathetic and parasympathetic branches plays a critical role in the regulation of physiological responses required for maintaining metabolic homeostasis. Organ-specific neural fibers can have profound effects on regulating key metabolic processes such as gluconeogenesis, lipolysis and hormonal secretion.  While new techniques in neuroscience and molecular genetics are revealing the specificity and diversity of neurons in the central nervous system, much remains unknown in the peripheral nervous system. 

     The Program Director for Neural Mechanisms of Metabolic Control should be familiar with the current state of science in this area to assess research needs and advance the field as it relates to metabolic disease.  It is expected that this research portfolio will be focused on basic mechanisms, emerging technologies, new models, and network or other bioinformatics analyses needed to integrate contemporary approaches in histology, opto- and chemogenetics.  The Program Director will be expected to identify emerging technologies, develop initiatives based on scientific priorities, advise potential applicants and administer grants and awards. The applicant must have a professional scientific degree (Ph.D. or M.D.), scientific management experience, and strong interpersonal and written communication skills.

Please prepare to apply to the upcoming job announcement for GS-12/13/14 HSA (Program Officer/Scientific Review Officer) through USAjobs.gov

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The University of Alabama at Birmingham* (UAB) Heersink School of Medicine

The University of Alabama at Birmingham (UAB) and the UAB Comprehensive Diabetes Center (UCDC) are leading the recruitment of up to 10 investigators for a major strategic portfolio increase across basic, translational, clinical, and population science research efforts in diabetes. Recruitment is for tenured, tenure-track, and non-tenure-earning faculty applicants with an MD, PhD or MD/PhD at all ranks and includes academic appointment in one or more of 27 academic departments across the Heersink SOM, many of which rank in the top 10 nationally in NIH funding.

All applications will be considered, but priority will be given to those with the following focus areas in diabetes and metabolism research:

  • single-cell biology
  • epigenetics
  • bioinformatics
  • investigator-initiated clinical trials
  • adult or pediatric longitudinal diabetes
  • studies
  • medical informatics
  • precision diabetes
  • translational type 1 and type 2 diabetes
  • research
  • population health research in diabetes

Interested candidates should send their CV, cover letter, and contact information with 3 references to  Dr. Josh Carter.

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Indiana Biosciences Research Institute

Indiana Biosciences Research Institute is offering Postdoctoral positions to study the protection of antigen-specific monoclonal antibodies and engineered T cells against type 1 diabetes, supported by federal and local fundings. Candidates must have Ph.D. and/or M.D. degrees in immunology, biology, or a related field. Candidates with expertise and skills in Immunology, autoimmune disease, and diabetes are strongly encouraged to apply.  In this position, you will work in a collaborative and interdisciplinary team to study immune interventions using both animal models and human samples. Candidates will also be encouraged to develop their own research interests. Interested candidates should send their CV, cover letter, and contact information with 3 references to Dr. Li Zhang.

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Joslin Diabetes Center, Harvard Medical School

Post-Doctoral Fellowship position in the Kulkarni Lab at Joslin Diabetes Center, Harvard Medical School.  One position is available immediately for a period of 3 years each. Applications are invited from individuals with a PhD or MD or MD PhD degrees. Candidates with expertise in Bioinformatics will be especially relevant. Prospective candidates should have expertise in handling large ‘omics’ databases and be willing to work closely with other Fellows in the lab to assist in analyses of biological data from diverse projects focused on Metabolism. These include but are not restricted to defining pathways and identifying mechanisms that regulate pancreatic (endocrine and exocrine) biology and inter-organ cross-talk in the overall maintenance of glucose homeostasis. Other projects include induced pluripotent stem cells, genetically engineered and humanized mouse models. Candidates will also be encouraged to develop their own research interests. Applicants for the position should provide a brief statement of research interests, CV, and the names of three references to Dr. Kulkarni.

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Rutgers, the State University of New Jersey

Rutgers, the State University of New Jersey, is seeking a Postdoctoral Fellow for the Child Health Institute of New Jersey. The position is available in El Ouaamari’s laboratory to investigate the role of the peripheral neurons in the regulation of systemic energy homeostasis in the context of obesity and diabetes. Self-driven, creative, resourceful and independent candidates with a PhD in neuroscience or neurobiology are encouraged to apply. Prior postdoctoral experience in neuroscience or related fields is preferred. Successful applicants will develop a research project focused on understanding how peripheral neurons control glucose and lipid homeostasis—with the long-term goal of identifying high-value biological data that can be harnessed to design neuromodulation-based strategies to counter obesity and diabetes. The candidate must be skilled in using in vitro and in vivo techniques for manipulating and monitoring neuronal activity and should have strong records of productivity and achievement. Preference will be given to applicants who have experience in islet biology as well. The successful candidate will also contribute to the training of undergraduate and graduate students and work closely with the PI on preparation and submission of research/review articles and grants.  Please send cover letter and CV to Dr. Abdelfattah El Ouaamari.

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University of Pittsburgh

The Freyberg laboratory at the University of Pittsburgh is offering Postdoctoral positions to study roles of dopamine in pancreatic hormone secretion and in diabetes. Candidates must have Ph.D. and/or M.D. degrees. Previous experience with molecular biology, mammalian cell and pancreatic islet culture, fluorescence microscopy is also preferred but not required, although candidates with experience in these skills are strongly encouraged to apply. Training in more advanced techniques is a key aim of the postdoctoral position; the biggest requirement is the enthusiasm and ambition of the candidate to make important contributions to our understanding of dopamine actions in metabolism. Interested candidates should send their CV, a one-page summary of their past research and future research interests, and the contact information for 2-3 references directly to Dr. Zachary Freyberg.

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Hollings Cancer Center at the Medical University of South Carolina

The laboratory of Dr. Leonardo Ferreira in the Department of Microbiology and Immunology and the Hollings Cancer Center at the Medical University of South Carolina is searching for a postdoctoral fellow to lead regulatory T cell (Treg) research projects in the lab. The objective of the Ferreira Lab is to design and develop engineered immune cell therapies for autoimmune disease and aging. The candidate must have a PhD in biology, immunology, or a related field, and have demonstrated quality publication of their work. Please send your CV, cover letter, and contact information with three references to  Dr. Leonardo Ferreira.

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The University of Chicago’s Department of Medicine

The University of Chicago’s Department of Medicine is searching for full-time physician scientist faculty members at any rank. Appointees will maintain a productive research program and provide patient care directly. Other responsibilities will include teaching and supervision of trainees and students. We are interested in applicants in any area of scientific investigation and clinical subspecialty, and especially welcome those whose research focus more broadly is in the areas of immunology/inflammation, diabetes, obesity, metabolism, sleep disorders, or cancer biology. Prior to the start of employment, qualified applicants must: 1) have a medical doctorate or equivalent, and 2) hold or be eligible for medical licensure in the State of Illinois. Please send your CV, cover letter, and contact information with 3 references to Dr. Mirmira.

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University of British Columbia

A new Stem Cell and Genome Editing Core Facility situated within the Kieffer Research Group University of British Columbia has an opportunity for a highly motivated and collaborative technician to support diverse regenerative medicine research initiatives. The candidate will assist with the dayto-day operation of the Core, will generate human induced pluripotent cells (iPSCs), and will culture and differentiate human embryonic stem cells (ESCs) and iPSCs down pancreatic lineages.  Candidates should submit a cover letter outlining research interests and fit with the laboratory’s research along with resume.

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University of Pennsylvania School of Medicine

The Voight lab invites applications for a computational Post-Doctoral position at the University of Pennsylvania School of Medicine, within the Department of Systems Pharmacology and Translational Therapeutics and the Department of Genetics. The lab focuses on translating discoveries from human genetics data into insights about the biological basis and genetic architecture of human disease (ultimately toward developing new therapeutics targets for human disease), and understanding selection during recent human evolution.  Adding some focal work on computational analyses for T2D. The candidate will have a MD, PhD, or equivalent doctorate, with a strong background in one or more of the following areas: statistics, biostatistics, population genetics, human genetics, genetic epidemiology, computational biology and/or genomics, bioinformatics.  To apply, please send (i) a cover letter that includes the names and contacts for three references and a short statement of research interests, and (ii) a current CV to: Dr. Benjamin Voight.

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Vanderbilt Diabetes Center

The Powers & Brissova research group in the Vanderbilt Diabetes Center is a seeking postdoctoral fellows to study human pancreas and islet biology with a focus on gene expression and developmental biology of single cells. We are especially interested individuals with computational or informatics expertise, multimodal, multiplex experience, or live cell imaging experience. Please send current CV to Dr. Al Powers.

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