A human anti-IL-2 antibody that potentiates regulatory T cells by a structure-based mechanism.
Trotta E, Bessette PH, Silveria SL, Ely LK, Jude KM, Le DT, Holst CR, Coyle A, Potempa M, Lanier LL, Garcia KC, Crellin NK, Rondon IJ, Bluestone JA. Nat Med. 2018 Jun 25. doi: 10.1038/s41591-018-0070-2. PMID:29942088