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Active Projects
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Dissecting Chimeric Antigen Receptor Function in Human Regulatory T Cells
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Humanized Mouse Avatars for T1D
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Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems
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Tregs as Vehicles for Targeted Delivery of Therapeutic Payload to Human Islets
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Closed Projects
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Analysis of Human Autoreactive T Cell Receptors in vivo
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Genetic Regulation of Human Beta Cell Destruction
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HLA multimer based characterization of Islet Resident CD4+ T Cells that Target Beta Cell Epitopes and Neo-epitopes
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Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function
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Identification of the Cognate Epitopes of Autoreactive T Cells in T1D
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Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells
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On the Plasticity of Beta-cell Antigen Recognition by Diabetogenic CD8 T cells
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Therapeutic Targeting of the Human Islet Environment
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Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance
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