Midhat Abdulreda, PhD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, Investigator

Ashu Agarwal, PhD

University of Miami

• Real-time Detection of Insulin Surrogate Markers within Physiomimetic Islet Microsystems, Investigator
• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Invesetigator

Joana Almaca, PhD

University of Miami

• Changes in Human Islet Microvasculature during Type 1 Diabetes, Investigator

Mark S. Anderson, MD, PhD

University of California, San Francisco

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator
• Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance, Investigator

Charles Ansong, PhD

Pacific Northwest National Laboratory

• The Proteome of Replicating Cells, Investigator
• Alternative RNA Splicing Events Contribute to the Onset of islet dysfunction in T1D, Investigator

Peter Arvan, PhD

• A Stress-Induced Vicious Cycle in the Development of T1D, Investigator

Mark Atkinson, PhD

University of Florida

• HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), Investigator
• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Dana Avrahami-Tzfati, PhD

Hadassah-Hebrew University

• The Role of Beta Cell Senescence in the Pathogenesis of Diabetes, Investigator

Michael Betts, PhD

University of Pennsylvania

• HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), co-Investigator

Jeffrey Bluestone, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Investigator
• Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance, Investigator

Rita Bottino, PhD

Allegheny Health Network

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Michael Brehm, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Investigator

Marcela Brissova, PhD

Vanderbilt University

• In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas, Investigator
• HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), co-Invetigator
• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Todd Brusko, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Peter Buchwald, PhD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, co-Investigator

Alejandro Caicedo, PhD

University of Miami

• In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas, Investigator
• High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Co-Investigator
• Real-time Detection of Insulin Surrogate Markers within Physiomimetic Islet Microsystems, Collaborator

Shuibing Chen, PhD

• Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression, Investigator

Amit Choudhary, PhD

Broad Institute

• Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Investigator
• One-compound, one-islet: A High-throughput Platform for Small-molecule Discovery, Investigator

Karen Christman, PhD, FAHA

University of California at San Diego

• Quantitative Mass Spectrometry Analysis of Human Islet and Pancreas ECM, Investigator
• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Co-Investigator

Remi Creusot, PhD

Columbia University

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Co-Investigator

Chunhua Dai, MD

Vanderbilt University

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Co-Investigator

George Daley, MD, PhD

Harvard Medical School

• Humanized Mouse Avatars for T1D, Investigator

Sangeeta Dhawan, PhD

City of Hope

• Targeting DNA Hydroxymethylation to Promote Human Beta Cell Function, Investigator

Juan Dominguez-Bendala, PhD

University of Miami

• High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Investigator

Yuval Dor, PhD

Hebrew University of Jerusalem

• Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, Investigator
• Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Co-Investigator
• The Proteome of Replicating Cells, Investigator

Decio Eizirik, MD, PhD

University of Brussels

• The Integrated Stress Response in Human Islets during Early T1D, Investigator

Abdelfattah El Ouaamari, PhD

Rutgers University

• Neuromodulation for Type 1 Diabetes: Harnessing Sensory Innervation to Promote Regeneration and Function of Insulin-Producing Cells., Investigator

Carmella Evans-Molina, MD, PhD

Indiana University

• The Integrated Stress Response in Human Islets during Early T1D, Investigator
• Workshop for Continued Harmonization of Beta Cell Death Assays, Investigator

Michael Feldman, MD, PhD

University of Pennsylvania

• HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator

Paul Gadue, PhD

Children's Hospital of Philadelphia

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator
• Generation of Functional Endocrine Cell Reporter Pluripotent Cell Lines, Investigator
• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

Kyle Gaulton, PhD

University of California, San Diego

• Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Investigator

Steven George, MD, PhD

University of California, Davis

• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Co-Investigator

Benjamin Glaser, MD

Hadassah-Hebrew University

• The Role of Beta Cell Senescence in the Pathogenesis of Diabetes, Investigator

Anna Gloyn, D Phil

Stanford University

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Robin Goland, MD

Columbia University

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Co-Investigator

David Gorkin, PhD

University of California, San Diego

• Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Co-Investigator

Carla Greenbaum, MD

Benaroya Research Institute

• Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Investigator

Dale Greiner, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Investigator

Markus Grompe, MD

Oregon Health & Science University

• Gene Therapy for Diabetes, Investigator

Manami Hara, PhD

• The Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

David Harlan, MD

University of Massachusetts Medical School

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator
• Humanized Mouse Avatars for T1D, Co-Investigator

Chuan He, PhD

University of Chicago

• Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes, Investigator

Matthias Hebrok, PhD

University of California, San Francisco

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator
• Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance, Investigator

Martin Hetzer, PhD

Salk Institute

• Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

Dirk Homann, MD

Mount Sinai Hospital

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, co-Investigator

Chris Hughes, PhD

University of California at Irvine

• Modular Monitoring of Hormone Release from Human Islets, Investigator
• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Investigator

Jing Hughes, PhD

• Primary Cilia in Human T1D Pancreas, Investigator

Dan Huh, PhD

University of Pennsylvania

• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

Eddie James, PhD

Benaroya Research Institute

• HLA multimer based characterization of Islet Resident CD4+ T Cells that Target Beta Cell Epitopes and Neo-epitopes, Investigator

Alok Joglekar, PhD

• Identification of the Cognate Epitopes of Autoreactive T Cells in T1D, Investigator

Klaus Kaestner, PhD

University of Pennsylvania

• Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, Investigator
• HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
• A New Immunodeficient Mouse Model with Stable Hyperglycemia for the Study of Human Beta-cells, Investigator
• Can Genomic Mosaicism explain the Lobular Nature of Type 1 Diabetes?, Investigator

Mark Kay, MD, PhD

Stanford University

• Gene Therapy for Diabetes, Investigator

Sally Kent, PhD

University of Massachusetts Medical School

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator
• Humanized Mouse Avatars for T1D, Co-Investigator

Seung Kim, MD, PhD

Stanford University

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
• Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator
• Linking Islet Cell Function and Identity from in vitro to in situ, Co-Investigator

Stephan Kissler, PhD

Joslin Diabetes Institute

• Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling, Investigator

Rohit Kulkarni, MD, PhD

Joslin Diabetes Center

• Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Investigator
• Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes, Invesigator
• One-compound, one-islet: A High-throughput Platform for Small-molecule Discovery, Investigator

Irina Kusmartseva, PhD

University of Florida

• HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), co-Investigator

Maggie Lam, PhD

• Alternative RNA Splicing Events Contribute to the Onset of islet dysfunction in T1D, Co-Investigator

Xiaoyong Lei, PhD

• The Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Wendell Lim, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Investigator

Amelia Linnemann, PhD

Indiana University School of Medicine

• Real-time in vivo Analysis of Islet Redox Dynamics, Investigator
• Functional and Molecular Characterization of the Human Islet Interferon Alpha Response, Investigator

Chengyang Liu, MD

• Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression, Co-Investigator

Emma Lundberg, PhD

KTH Royal Institute of Technology

• Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

Patrick MacDonald, PhD

University of Alberta

• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
• Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

Rene Maehr, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Co-Investigator

Dustin Maly, PhD

University of Washington

• Partial Antagonists of IRE1 RNASE - 'pairs' - to treat type 1 diabetes, Investigator

Clayton Mathews, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Douglas Melton, PhD

Harvard University

• Humanized Mouse Avatars for T1D, Investigator

Thomas Metz, PhD

Pacific Northwest National Laboratory

• The Integrated Stress Response in Human Islets during Early T1D, Investigator

Everett Meyer, MD, PhD

Stanford University

• Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator

Raghavendra Mirmira, MD, PhD

Indiana University

• The Integrated Stress Response in Human Islets during Early T1D, Investigator

Jason Moore, PhD

University of Pennsylvania

• HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator

Ali Naji, MD, PhD

University of Pennsylvania

• Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, co-Investigator
• HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator
• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Co-Investigator

Hiroyuki Nakai, MD, PhD

Oregon Health & Science University

• Gene Therapy for Diabetes, Investigator

Ernesto Nakayasu, PhD

Pacific Northwest National Laboratory

• Alternative RNA Splicing Events Contribute to the Onset of islet dysfunction in T1D, Co-Investigator

scott_oakes

• The Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Galya Orr, PhD

Pacific Northwest National Laboratory

• Alternative RNA Splicing Events Contribute to the Onset of islet dysfunction in T1D, Co-Investigator

Feroz Papa, MD, PhD

University of California, San Francisco

• Partial Antagonists of IRE1 RNASE - 'pairs' - to treat type 1 diabetes, Investigator

Audrey Parent, PhD

University of California, San Francisco

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

Stephen Parker, PhD

• Determining the Intrinsic and Environmental Signal Contributing to Early T1D Progression, Investigator

Ricardo Pastori, PhD

University of Miami

• High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Investigator

Ed Phelps, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Co-Investigator

Al Powers, MD

Vanderbilt University

• HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), Investigator
• HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator
• Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator
• Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Co-Investigator

Sebastian Preissl, PhD

University of California, San Diego

• Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Co-Investigator

Stephen Quake, PhD

Stanford University

• Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

Sasanka Ramanadham, PhD

• The Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Camillo Ricordi, MD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, co-Investigator
• High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Co-Investigator

Michael Roper, PhD

Florida State University

• Modular Monitoring of Hormone Release from Human Islets, Investigator

Kole Roybal, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Co-Investigator

Holger Russ, PhD

University of Colorado, Denver

• Elucidating the Human Beta Cell Translatome in Health and Disease, Investigator

Maike Sander, MD

University of California, San Diego

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator
• Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Investigator
• A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Investigator

Leslie Satin, PhD

• A Stress-Induced Vicious Cycle in the Development of T1D, Investigator

Desmond Schatz, MD

University of Florida

• Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Investigator

Paolo Serafini, PhD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, Investigator

Anath Shalev, MD

University of Alabama at Birmingham

• Development of an Early Diagnostic Biomarker and Novel Treatment Strategy for T1D, Investigator

Leonard Shultz, PhD

The Jackson Laboratory

• Humanized Mouse Avatars for T1D, Investigator

Scott Soleimanpour, PhD

• A Stress-Induced Vicious Cycle in the Development of T1D, Investigator

Stephan Speier, PhD

Paul-Langerhans-Institute Dresden

• In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas, Investigator

Cherie Stabler, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Ben Stanger, MD, PhD

University of Pennsylvania

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator
• Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

Lawrence Stern, PhD

University of Massachusetts Medical Center

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator

Doris Stoffers, MD, PhD

University of Pennsylvania

• HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), co-Investigator
• HPAP T2D: Human Pancreas Analysis Program (Univ. Pennsylvania), Investigator

Lori Sussel, PhD

University of Colorado, Denver

• Alternative RNA Splicing Events Contribute to the Onset of islet dysfunction in T1D, Investigator

Megan Sykes, MD

Columbia University

• Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

Qizhi Tang, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Co-Investigator

Naohiro Terada, MD, PhD

University of Florida

• Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Co-Investigator

Golnaz Vahedi, PhD

• Dissecting Transcriptomics and Epigenomic Signatures of Immune Cells in T1D, Investigator

Prashanth Vallabhajosyula, MD

Yale University

• Discovery and Investigation of Noninvasive Diagnostic Potential of Circulating Pancreatic Islet Beta Cell Exosomes as Biomarkers of Beta Cell Injury, Investigator

Bridget Wagner, PhD

Broad Institute

• Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Co-Investigator
• One-compound, one-islet: A High-throughput Platform for Small-molecule Discovery, Investigator

Bobbie-Jo Webb-Robertson, PhD

Pacific Northwest National Laboratory

• The Integrated Stress Response in Human Islets during Early T1D, Investigator

Ryan White, PhD

University of Cincinnati

• Modular Monitoring of Hormone Release from Human Islets, Investigator

Wenting Wu, PhD

• The Integrated Stress Response in Human Islets during Early T1D, Co-Investigator

Mingder Yang, PhD

University of Florida

• HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), co-Investigator

Ken Zaret, PhD

University of Pennsylvania

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator

Joe Zhou, PhD

Weill Cornell Medical College

• Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling, Investigator