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Investigators

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A

Midhat Abdulreda, PhD

University of Miami

Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, Investigator

Ashu Agarwal, PhD

University of Miami

Real-time Detection of Insulin Surrogate Markers within Physiomimetic Islet Microsystems, Investigator
Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Invesetigator

Joana Almaca, PhD

University of Miami

Changes in Human Islet Microvasculature during Type 1 Diabetes, Investigator

Mark S. Anderson, MD, PhD

University of California, San Francisco

Charles Ansong, PhD

Pacific Northwest National Laboratory

Mark Atkinson, PhD

University of Florida

Dana Avrahami-Tzfati, PhD

Hadassah-Hebrew University

The Role of Beta Cell Senescence in the Pathogenesis of Diabetes, Investigator

B

Michael Betts, PhD

University of Pennsylvania

HPAP T1D: Integrated Human Pancreas Analysis Program (Univ. Pennsylvania), co-Investigator

Jeffrey Bluestone, PhD

University of California, San Francisco

Bernd Bodenmiller, PhD

University of Zurich

Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Investigator

Rita Bottino, PhD

Allegheny Health Network

HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Michael Brehm, PhD

University of Massachusetts Medical School

Humanized Mouse Avatars for T1D, Investigator

Marcela Brissova, PhD

Vanderbilt University

Todd Brusko, PhD

University of Florida

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Peter Buchwald, PhD

University of Miami

Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, co-Investigator

Kristin Burnum-Johnson, PhD

Pacific Northwest National Laboratory

Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

C

Long Cai, PhD

California Institute of Technology

High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Alejandro Caicedo, PhD

University of Miami

Richard Caprioli, PhD

Vanderbilt University

High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Amit Choudhary, PhD

Broad Institute

Karen Christman, PhD, FAHA

University of California at San Diego

Remi Creusot, PhD

Columbia University

Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Co-Investigator

D

Chunhua Dai, MD

Vanderbilt University

HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Co-Investigator

George Daley, MD, PhD

Harvard Medical School

Humanized Mouse Avatars for T1D, Investigator

Sangeeta Dhawan, PhD

City of Hope

Targeting DNA Hydroxymethylation to Promote Human Beta Cell Function, Investigator

Juan Dominguez-Bendala, PhD

University of Miami

High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Investigator

Yuval Dor, PhD

Hebrew University of Jerusalem

E

Abdelfattah El Ouaamari, PhD

Rutgers University

Neuromodulation for Type 1 Diabetes: Harnessing Sensory Innervation to Promote Regeneration and Function of Insulin-Producing Cells., Investigator

Carmella Evans-Molina, MD, PhD

Indiana University

Workshop for Continued Harmonization of Beta Cell Death Assays, Investigator

F

Michael Feldman, MD, PhD

University of Pennsylvania

G

Paul Gadue, PhD

Children's Hospital of Philadelphia

Kyle Gaulton, PhD

University of California, San Diego

Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Investigator

Steven George, MD, PhD

University of California, Davis

A 3D Vascularized Islet Biomimetic to Model Type 1 Diabetes, Co-Investigator

Benjamin Glaser, MD

Hadassah-Hebrew University

The Role of Beta Cell Senescence in the Pathogenesis of Diabetes, Investigator

Anna Gloyn, D Phil

Stanford University

HPAP T2D: Human Pancreas Analysis Program (Vanderbilt Univ.), Investigator

Robin Goland, MD

Columbia University

Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Co-Investigator

David Gorkin, PhD

University of California, San Diego

Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Co-Investigator

Viviana Gradinaru, PhD

California Institute of Technology

High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Carla Greenbaum, MD

Benaroya Research Institute

Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Investigator

Dale Greiner, PhD

University of Massachusetts Medical School

Humanized Mouse Avatars for T1D, Investigator

Markus Grompe, MD

Oregon Health & Science University

Gene Therapy for Diabetes, Investigator

H

David Harlan, MD

University of Massachusetts Medical School

Chuan He, PhD

University of Chicago

Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes, Investigator

Matthias Hebrok, PhD

University of California, San Francisco

Pedro Herrera, PhD

University of Geneva

Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Investigator

Martin Hetzer, PhD

Salk Institute

Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

Dirk Homann, MD

Mount Sinai Hospital

Chris Hughes, PhD

University of California at Irvine

Dan Huh, PhD

University of Pennsylvania

Microphysiological Systems for Modeling Autoimmunity in Type 1 Diabetes, Investigator

J

Eddie James, PhD

Benaroya Research Institute

HLA multimer based characterization of Islet Resident CD4+ T Cells that Target Beta Cell Epitopes and Neo-epitopes, Investigator

K

Klaus Kaestner, PhD

University of Pennsylvania

Mark Kay, MD, PhD

Stanford University

Gene Therapy for Diabetes, Investigator

Sally Kent, PhD

University of Massachusetts Medical School

Seung Kim, MD, PhD

Stanford University

Stephan Kissler, PhD

Joslin Diabetes Institute

Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling, Investigator

Rohit Kulkarni, MD, PhD

Joslin Diabetes Center

Irina Kusmartseva, PhD

University of Florida

HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), co-Investigator

L

Julia Laskin, PhD

Pacific Northwest National Laboratory

Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

Wendell Lim, PhD

University of California, San Francisco

Therapeutic Targeting of the Human Islet Environment, Investigator

Amelia Linnemann, PhD

Indiana University School of Medicine

Real-time in vivo Analysis of Islet Redox Dynamics, Investigator

Emma Lundberg, PhD

KTH Royal Institute of Technology

Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

M

Patrick MacDonald, PhD

University of Alberta

Rene Maehr, PhD

University of Massachusetts Medical School

Humanized Mouse Avatars for T1D, Co-Investigator

Dustin Maly, PhD

University of Washington

Partial Antagonists of IRE1 RNASE - 'pairs' - to treat type 1 diabetes, Investigator

Clayton Mathews, PhD

University of Florida

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Douglas Melton, PhD

Harvard University

Humanized Mouse Avatars for T1D, Investigator

Thomas Metz, PhD

Pacific Northwest National Laboratory

Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

Everett Meyer, MD, PhD

Stanford University

Therapeutic Targeting of Human Islets with Recombinant Regulatory T Cells, Investigator

Jason Moore, PhD

University of Pennsylvania

N

Ali Naji, MD, PhD

University of Pennsylvania

Hiroyuki Nakai, MD, PhD

Oregon Health & Science University

Gene Therapy for Diabetes, Investigator

Harry Nick, PhD

University of Florida

Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, co-Investigator

Jeremy Norris, PhD

Vanderbilt University

High-Resolution Analysis of Juvenile Human Pancreas Maturation, Co-Investigator

O

Galya Orr, PhD

Pacific Northwest National Laboratory

Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

P

Feroz Papa, MD, PhD

University of California, San Francisco

Partial Antagonists of IRE1 RNASE - 'pairs' - to treat type 1 diabetes, Investigator

Audrey Parent, PhD

University of California, San Francisco

Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

Ricardo Pastori, PhD

University of Miami

High-Resolution Characterization of Human Ductal Progenitor Cells and their Regeneration Potential, Investigator

Ed Phelps, PhD

University of Florida

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Co-Investigator

Al Powers, MD

Vanderbilt University

Sebastian Preissl, PhD

University of California, San Diego

Single Cell Analysis of the Human Pancreas in Type 1 Diabetes, Co-Investigator

Q

Stephen Quake, PhD

Stanford University

Linking Islet Cell Function and Identity from in vitro to in situ, Investigator

R

Camillo Ricordi, MD

University of Miami

Michael Roper, PhD

Florida State University

Modular Monitoring of Hormone Release from Human Islets, Investigator

Kole Roybal, PhD

University of California, San Francisco

Therapeutic Targeting of the Human Islet Environment, Co-Investigator

Holger Russ, PhD

University of Colorado, Denver

Elucidating the Human Beta Cell Translatome in Health and Disease, Investigator

S

Maike Sander, MD

University of California, San Diego

Desmond Schatz, MD

University of Florida

Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Investigator

Paolo Serafini, PhD

University of Miami

Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, Investigator

Anath Shalev, MD

University of Alabama at Birmingham

Development of an Early Diagnostic Biomarker and Novel Treatment Strategy for T1D, Investigator

Leonard Shultz, PhD

The Jackson Laboratory

Humanized Mouse Avatars for T1D, Investigator

Stephan Speier, PhD

Paul-Langerhans-Institute Dresden

In situ Analysis of Functional Endocrine, Vascular, and Immune Cell Interactions During Early Postnatal Development of the Human Pancreas, Investigator

Cherie Stabler, PhD

University of Florida

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Investigator

Ben Stanger, MD, PhD

University of Pennsylvania

Lawrence Stern, PhD

University of Massachusetts Medical Center

Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator

Doris Stoffers, MD, PhD

University of Pennsylvania

Lori Sussel, PhD

University of Colorado, Denver

Single Cell Resolution of Omics Analysis of T1D Islets, Investigator

Megan Sykes, MD

Columbia University

Modeling Autoimmune Pathogenesis and Beta Cell Destruction by T1D Immune Systems, Investigator

T

Qizhi Tang, PhD

University of California, San Francisco

Therapeutic Targeting of the Human Islet Environment, Co-Investigator

Naohiro Terada, MD, PhD

University of Florida

Engineering a Human Microphysiological System for the Characterization of Islet-Immune Interactions, Co-Investigator

Fabrizio Thorel, PhD

University of Geneva

Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, co-Investigator

V

Prashanth Vallabhajosyula, MD

Yale University

Discovery and Investigation of Noninvasive Diagnostic Potential of Circulating Pancreatic Islet Beta Cell Exosomes as Biomarkers of Beta Cell Injury, Investigator

W

Bridget Wagner, PhD

Broad Institute

Clive Wasserfall

University of Florida

Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Collaborator

Ryan White, PhD

University of Cincinnati

Modular Monitoring of Hormone Release from Human Islets, Investigator

Christopher Wright, D Phil

Vanderbilt University

High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Y

Mingder Yang, PhD

University of Florida

HPAP T1D: Integrated Program for Human Pancreas Analysis (Vanderbilt Univ.), co-Investigator

Z

Ken Zaret, PhD

University of Pennsylvania

Functional Testing of Candidate HSC-derived Islet Cells, Investigator

Joe Zhou, PhD

Weill Cornell Medical College

Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling, Investigator