Midhat Abdulreda, PhD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, Investigator

Domenico Accili, MD

Columbia University

• Epigenetic, Protein, and Cellular Biomarkers of Beta Cell Function in T1D, Co-Investigator

Ashu Agarwal, PhD

University of Miami

• Engineering a Human Physiomimetic Islet Microsystem, Investigator
• Real-time Detection of Insulin Surrogate Markers within Physiomimetic Islet Microsystems, Investigator

Mark S. Anderson, MD, PhD

University of California, San Francisco

• Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance, Investigator

Charles Ansong, PhD

Pacific Northwest National Laboratory

• The Proteome of Replicating Cells, Investigator
• Single Cell Resolution of Omics Analysis of T1D Islets, Investigator

Mark Atkinson, PhD

University of Florida

• Defining Islet Heterogeneity Using Single Islet Transcriptomics, Co-Investigator
• Integrated Program for Human Pancreas Analysis, Investigator
• Antibodies for Beta-Cell Subtype Identification by Immunohistochemistry, Investigator
• Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Investigator

Dana Avrahami-Tzfati, PhD

Hadassah-Hebrew University

• Epigenetic Rejuvenation of Human Beta-Cells, Co-Investigator
• The Role of Beta Cell Senescence in the Pathogenesis of Diabetes, Investigator

Michael Betts, PhD

University of Pennsylvania

• Penn Integrated Human Pancreas Analysis Program, co-Investigator

Sangeeta Bhatia, MD, PhD

Massachusetts Institute of Technology

• A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator

Jeffrey Bluestone, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Investigator
• Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance, Investigator

Bernd Bodenmiller, PhD

University of Zurich

• Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Investigator

Rita Bortell, PhD

University of Massachusetts Medical School

Rita Bottino, PhD

Allegheny Health Network

• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Co-Investigator

Michael Brehm, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Investigator

Marcela Brissova, PhD

Vanderbilt University

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Co-Investigator
• Integrated Program for Human Pancreas Analysis, co-Invetigator
• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Co-Investigator

Todd Brusko, PhD

University of Florida

• Genetic Regulation of Human Beta Cell Destruction, Co-Investigator
• Islet-reactive TCR clones in humanized mice generated with type 1 diabetes patient vs. healthy control hematopoietic stem cells, Investigator
• Characterization of in silico Reconstruction of TCRs for Modeling Autoreactive T cells in T1D, Investigator

Peter Buchwald, PhD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, co-Investigator
• Engineering a Human Physiomimetic Islet Microsystem, Investigator

Kristin Burnum-Johnson, PhD

Pacific Northwest National Laboratory

• Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

Long Cai, PhD

California Institute of Technology

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Martha Campbell-Thompson, DVM PhD

University of Florida

• Defining Islet Heterogeneity Using Single Islet Transcriptomics, Investigator

Richard Caprioli, PhD

Vanderbilt University

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Xiaojuan Chen, MD, PhD

Columbia University

• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Co-Investigator

Chris Chen, MD, PhD

Boston University

• A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator

Hao Chen, PhD

University Tennessee

• Defining Islet Heterogeneity Using Single Islet Transcriptomics, Co-Investigator

Jing Chen, PhD

University of Florida

• Genetic Regulation of Human Beta Cell Destruction, Co-Investigator

Amit Choudhary, PhD

Broad Institute

• Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Investigator

Karen Christman, PhD, FAHA

University of California at San Diego

• A 3D Biomimetic Human Islet to Model Beta Cell Function in Health and Disease, Investigator
• Quantitative Mass Spectrometry Analysis of Human Islet and Pancreas ECM, Investigator

Chunhua Dai, MD

Vanderbilt University

• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Co-Investigator

George Daley, MD, PhD

Harvard Medical School

• Humanized Mouse Avatars for T1D, Investigator

Nichole Danzl, PhD

Columbia University

• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Co-Investigator

Yuval Dor, PhD

Hebrew University of Jerusalem

• Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, Investigator
• Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Co-Investigator
• Non-invasive Diagnosis of Human Beta Cell Damage and Death, Co-Investigator
• The Proteome of Replicating Cells, Investigator

Dieter Egli, PhD

Columbia University

• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Co-Investigator

Decio Eizirik, MD, PhD

University of Brussels

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Investigator

Carmella Evans-Molina, MD, PhD

Indiana University

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Investigator
• Workshop for Continued Harmonization of Beta Cell Death Assays, Investigator

Michael Feldman, MD, PhD

University of Pennsylvania

• Penn Integrated Human Pancreas Analysis Program, co-Investigator

Jorge Ferrer, MD, PhD

Imperial College of London

• Non-invasive Diagnosis of Human Beta Cell Damage and Death, Co-Investigator

Kenichiro Furuyama, MD, PhD

University of Geneva

• Beta-cell Regeneration by Islet Cell Type Interconversion: Exploiting Islet Cell Plasticity for Diabetes Recovery, Co-Investigator

Paul Gadue, PhD

Children's Hospital of Philadelphia

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator
• Generation of Functional Endocrine Cell Reporter Pluripotent Cell Lines, Investigator
• A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator

Steven George, MD, PhD

University of California, Davis

• A 3D Biomimetic Human Islet to Model Beta Cell Function in Health and Disease, Investigator

Ivan Gerling, PhD

University of Tennessee

• Defining Islet Heterogeneity Using Single Islet Transcriptomics, Investigator

Ronald Gill, PhD

University of Colorado at Denver

• Analysis of Human Autoreactive T Cell Receptors in vivo, Investigator

Benjamin Glaser, MD

Hadassah-Hebrew University

• Epigenetic Rejuvenation of Human Beta-Cells, Investigator
• The Role of Beta Cell Senescence in the Pathogenesis of Diabetes, Investigator

Robin Goland, MD

Columbia University

• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Co-Investigator

Peter Gottlieb, MD

University of Colorado at Denver

• Analysis of Human Autoreactive T Cell Receptors in vivo, Co-Investigator

Viviana Gradinaru, PhD

California Institute of Technology

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Carla Greenbaum, MD

Benaroya Research Institute

• Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Investigator

Dale Greiner, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Investigator

Markus Grompe, MD

Oregon Health & Science University

• In vivo Targeting of Diabetes-relevant Human Cell Types with rAAV Vectors, Investigator
• Antibodies for Beta-Cell Subtype Identification by Immunohistochemistry, Investigator

David Harlan, MD

University of Massachusetts Medical School

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator
• Humanized Mouse Avatars for T1D, Co-Investigator

Chuan He, PhD

University of Chicago

• Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes, Investigator

Matthias Hebrok, PhD

University of California, San Francisco

• Using Human Stem Cell-derived Thymic Epithelium to Remodel T1D Immune Tolerance, Investigator

Kevan Herold, MD

Yale University

• Epigenetic, Protein, and Cellular Biomarkers of Beta Cell Function in T1D, Investigator

Pedro Herrera, PhD

University of Geneva

• Beta-cell Regeneration by Islet Cell Type Interconversion: Exploiting Islet Cell Plasticity for Diabetes Recovery, Investigator
• Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, Investigator

Dirk Homann, MD

Mount Sinai Hospital

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, co-Investigator
• Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator

Chris Hughes, PhD

University of California at Irvine

• A 3D Biomimetic Human Islet to Model Beta Cell Function in Health and Disease, Investigator
• Modular Monitoring of Hormone Release from Human Islets, Investigator

Dan Huh, PhD

University of Pennsylvania

• A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator

Klaus Kaestner, PhD, MS

University of Pennsylvania

• Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, Investigator
• Epigenetic Rejuvenation of Human Beta-Cells, Investigator
• Penn Integrated Human Pancreas Analysis Program, Investigator
• A New Immunodeficient Mouse Model with Stable Hyperglycemia for the Study of Human Beta-cells, Investigator
• Can Genomic Mosaicism explain the Lobular Nature of Type 1 Diabetes?, Investigator
• Mass Spectrometry-based Proteome Maps for Human Islet Cells, Investigator

John Kappler, PhD

National Jewish Medical & Research Center

• Analysis of Human Autoreactive T Cell Receptors in vivo, Co-Investigator

Jeff Karp, PhD

Brigham and Women's Hospital

• Islet on a Chip, Co-Investigator

Mark Kay, MD, PhD

Stanford University

• In vivo Targeting of Diabetes-relevant Human Cell Types with rAAV Vectors, Investigator

Sally Kent, PhD

University of Massachusetts Medical School

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator
• Characterization of in silico Reconstruction of TCRs for Modeling Autoreactive T cells in T1D, Investigator

Seung Kim, MD, PhD

Stanford University

• CAR T Cell Targeting of Human Islets, Investigator
• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Investigator
• Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator

Stephan Kissler, PhD

Joslin Diabetes Institute

• Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling, Investigator

Rohit Kulkarni, MD, PhD

Joslin Diabetes Center

• Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Investigator
• Interrogation of Dynamic RNA Modifications in Beta Cells in Type 1 Diabetes, Invesigator
• Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Investigator

Irina Kusmartseva, PhD

University of Florida

• Integrated Program for Human Pancreas Analysis, co-Investigator

Julia Laskin, PhD

Pacific Northwest National Laboratory

• Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

Ying Li

University of Floria

Wendell Lim, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Investigator

Rene Maehr, PhD

University of Massachusetts Medical School

• Humanized Mouse Avatars for T1D, Co-Investigator

Mark Mamula, PhD

Yale University

• Epigenetic, Protein, and Cellular Biomarkers of Beta Cell Function in T1D, Co-Investigator

Clayton Mathews, PhD

University of Florida

• Defining Islet Heterogeneity Using Single Islet Transcriptomics, Co-Investigator
• Genetic Regulation of Human Beta Cell Destruction, Investigator
• Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator
• Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Investigator

Jason McDermott, PhD

Pacific Northwest National Laboratory

• Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Co-Investigator

Douglas Melton, PhD

Harvard University

• Biomarkers for Diabetes using Stem Cell-derived Beta Cells, Investigator
• Humanized Mouse Avatars for T1D, Investigator
• Islet on a Chip, Investigator

Thomas Metz, PhD

Pacific Northwest National Laboratory

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Investigator
• Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

Everett Meyer, MD, PhD

Stanford University

• CAR T Cell Targeting of Human Islets, Investigator

Aaron Michels, MD

University of Colorado at Denver

• Analysis of Human Autoreactive T Cell Receptors in vivo, Co-Investigator

Raghavendra Mirmira, MD, PhD

Indiana University

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Investigator

Jason Moore, PhD

University of Pennsylvania

• Penn Integrated Human Pancreas Analysis Program, co-Investigator

Margaret Morris, PhD

Eastern Virginia Medical School

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Co-Investigator

Jerry Nadler, MD

Eastern Virginia Medical School

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Investigator

Ali Naji, MD, PhD

University of Pennsylvania

• Drivers and Consequences of Beta Cell DNA Damage in Type 1 Diabetes, co-Investigator
• Penn Integrated Human Pancreas Analysis Program, Investigator

Hiroyuki Nakai, MD, PhD

Oregon Health & Science University

• In vivo Targeting of Diabetes-relevant Human Cell Types with rAAV Vectors, Investigator

Maki Nakayama, MD, PhD

University of Colorado at Denver

• Analysis of Human Autoreactive T Cell Receptors in vivo, Co-Investigator
• Characterization of in silico Reconstruction of TCRs for Modeling Autoreactive T cells in T1D, Investigator

Ernesto Nakayasu, PhD

Pacific Northwest National Laboratory

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Co-Investigator

Harry Nick, PhD

University of Florida

• Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, co-Investigator

Jeremy Norris, PhD

Vanderbilt University

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Julius Nyalwidhe, PhD

Eastern Virginia Medical School

• Biomarkers of Beta Cell Stress in Type 1 Diabetes (BetaMarker), Co-Investigator

Galya Orr, PhD

Pacific Northwest National Laboratory

• Single Cell Resolution of Omics Analysis of T1D Islets, co-Investigator

Kit Parker, PhD

Harvard University

• Islet on a Chip, Co-Investigator

Vladislav Petyuk, PhD

Pacific Northwest National Laboratory

• Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Co-Investigator

Al Powers, MD

Vanderbilt University

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator
• Integrated Program for Human Pancreas Analysis, Investigator
• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Investigator
• Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator

Wei-Jun Qian, PhD

Pacific Northwest National Laboratory

• Mass Spectrometry-based Proteome Maps for Human Islet Cells, Investigator
• Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Investigator

Camillo Ricordi, MD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, co-Investigator
• Engineering a Human Physiomimetic Islet Microsystem, Investigator

Michael Roper, PhD

Florida State University

• Modular Monitoring of Hormone Release from Human Islets, Investigator

Derrick Rossi, PhD

Children’s Hospital Corp

Kole Roybal, PhD

• Therapeutic Targeting of the Human Islet Environment, Co-Investigator

Maike Sander, MD

University of California, San Diego

• A 3D Biomimetic Human Islet to Model Beta Cell Function in Health and Disease, Investigator
• Functional Testing of Candidate HSC-derived Islet Cells, Investigator

Alexei Savinov, MD

Sanford Research/Univ. of South Dakota

• Genetic Regulation of Human Beta Cell Destruction, Co-Investigator

Desmond Schatz, MD

University of Florida

• Non-invasive Detection of Cell Death in Type 1 Diabetes: Insight into Novel Disease Mechanisms, Investigator
• Non-invasive Diagnosis of Human Beta Cell Damage and Death, Investigator

Paolo Serafini, PhD

University of Miami

• Aptamer Chimeras for the in vivo Modulation of Beta Cell Mass and Immunogenicity, Investigator

Anath Shalev, MD

University of Alabama at Birmingham

• Targeting TXNIP to Enhance Beta Cell Mass in T1D, Invesigator

Ruth Shemer, PhD

Hebrew University of Jerusalem

• Non-invasive Diagnosis of Human Beta Cell Damage and Death, Co-Investigator

Tujin Shi, PhD

Pacific Northwest National Laboratory

• Regulatory Networks and Biomarkers of Beta-cell Dysfunction and Apoptosis, Co-Investigator

Leonard Shultz, PhD

The Jackson Laboratory

• Humanized Mouse Avatars for T1D, Investigator

Hans Snoeck, MD, PhD

Columbia University

• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Co-Investigator

Cherie Stabler, PhD

University of Florida

• Engineering a Human Physiomimetic Islet Microsystem, Investigator

Ben Stanger, MD, PhD

University of Pennsylvania

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator
• A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator

Lawrence Stern, PhD

University of Massachusetts Medical Center

• Human Islet-Infiltrating T cell Biology: Reactivity, Structure and Function, Investigator

Andrew Stewart, MD

Mount Sinai Hospital

• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Investigator
• Exploiting the power of CyTOF/Mass Cytometry (MC) to elucidate the complex interactions of islet and immune cells in human type 1 diabetes pancreata, Investigator

Doris Stoffers, MD, PhD

University of Pennsylvania

• Penn Integrated Human Pancreas Analysis Program, co-Investigator

Natasa Strbo, MD

University of Miami

Philip Streeter, PhD

Oregon Health & Science University

• CAR T Cell Targeting of Human Islets, co-Investigator
• Antibodies for Beta-Cell Subtype Identification by Immunohistochemistry, Investigator

Lori Sussel, PhD

University of Colorado, Denver

• Single Cell Resolution of Omics Analysis of T1D Islets, Investigator

Megan Sykes, MD

Columbia University

• Islet-reactive TCR clones in humanized mice generated with type 1 diabetes patient vs. healthy control hematopoietic stem cells, Investigator
• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Investigator

Qizhi Tang, PhD

University of California, San Francisco

• Therapeutic Targeting of the Human Islet Environment, Co-Investigator

Naohiro Terada, MD, PhD

University of Florida

• Genetic Regulation of Human Beta Cell Destruction, Co-Investigator

Fabrizio Thorel, PhD

University of Geneva

• Beta-cell Regeneration by Islet Cell Type Interconversion: Exploiting Islet Cell Plasticity for Diabetes Recovery, Co-Investigator
• Single-Cell Analyses of Human Islets in T1D Using Highly Multiplexed Imaging, co-Investigator

Bridget Wagner, PhD

Broad Institute

• Development of Small Molecule-based Methods for Targeted Cargo Delivery to Beta Cells, Co-Investigator

Mark Wallet, PhD

University of Florida

• Genetic Regulation of Human Beta Cell Destruction, Co-Investigator

Peng Wang, PhD

Mount Sinai Hospital

• Molecular Mechanisms of Physiologic Beta Cell Growth in Juvenile Human Pancreas, Co-Investigator

Ryan White, PhD

University of Cincinnati

• Modular Monitoring of Hormone Release from Human Islets, Investigator

Christopher Wright, D Phil

Vanderbilt University

• High-Resolution Analysis of Juvenile Human Pancreas Maturation, Investigator

Yong-Guang Yang, MD, PhD

Columbia University

• Mice with Autologous Human T1D-Derived Immune Systems and iPSC-Derived Beta Cells, Co-Investigator

Mingder Yang, PhD

University of Florida

• Integrated Program for Human Pancreas Analysis, co-Investigator

Ken Zaret, PhD

University of Pennsylvania

• Functional Testing of Candidate HSC-derived Islet Cells, Investigator
• A Vascularized 3D Biomimetic for Islet Function and Physiology, Investigator

Joe Zhou, PhD

Harvard University

• Generating Novel Sources of Functional Human Insulin-secreting Cells for T1D Modeling, Investigator